scholarly journals Molecular recognition of HIV-1 RNAs with branched peptides

2019 ◽  
pp. 373-400
Author(s):  
Ashley N. Peralta ◽  
Yumin Dai ◽  
Chringma Sherpa ◽  
Stuart F.J. Le Grice ◽  
Webster L. Santos
Keyword(s):  
Molecular Recognition ◽  
Branched Peptides ◽  
Hiv 1

A possible mechanism of molecular recognition for the reverse transcriptase of HIV-1

1992 ◽  
Vol 44 (S19) ◽  
pp. 225-253 ◽  
Author(s):  
Joaquim Delphino Da Motta Neto ◽  
Michael Charles Zerner ◽  
Ricardo Bicca De Alencastro
Keyword(s):  
Molecular Recognition ◽  
Reverse Transcriptase ◽  
Hiv 1

Molecular recognition in the HIV-1 capsid/cyclophilin A complex 1 1Edited by J. A. Wells

1997 ◽  
Vol 269 (5) ◽  
pp. 780-795 ◽  
Author(s):  
Sanghee Yoo ◽  
David G Myszka ◽  
Chin-yah Yeh ◽  
Maureen McMurray ◽  
Christopher P Hill ◽  
...  
Keyword(s):  
Molecular Recognition ◽  
Cyclophilin A ◽  
Hiv 1

scholarly journals A substrate selected by phage display exhibits enhanced side-chain hydrogen bonding to HIV-1 protease

2018 ◽  
Vol 74 (7) ◽  
pp. 690-694 ◽  
Author(s):  
Ian W. Windsor ◽  
Ronald T. Raines
Keyword(s):  
Crystal Structure ◽  
Hydrogen Bonding ◽  
Molecular Recognition ◽  
Hydrogen Bonds ◽  
Phage Display ◽  
Directed Evolution ◽  
Side Chain ◽  
Endogenous Substrates ◽  
Hiv 1 ◽  
Additional Hydrogen

Crystal structures of inactive variants of HIV-1 protease bound to peptides have revealed how the enzyme recognizes its endogenous substrates. The best of the known substrates is, however, a nonnatural substrate that was identified by directed evolution. The crystal structure of the complex between this substrate and the D25N variant of the protease is reported at a resolution of 1.1 Å. The structure has several unprecedented features, especially the formation of additional hydrogen bonds between the enzyme and the substrate. This work expands the understanding of molecular recognition by HIV-1 protease and informs the design of new substrates and inhibitors.

A new paradigm in molecular recognition? specific antibody binding to membrane-inserted HIV-1 epitopes

2011 ◽  
Vol 24 (4) ◽  
pp. 642-646 ◽  
Author(s):  
José L. Nieva ◽  
Beatriz Apellaniz ◽  
Nerea Huarte ◽  
Maier Lorizate
Keyword(s):  
Molecular Recognition ◽  
Specific Antibody ◽  
Antibody Binding ◽  
New Paradigm ◽  
Hiv 1

Insights on HIV-1 Tat:P/CAF bromodomain molecular recognition from in vivo experiments and molecular dynamics simulations

2005 ◽  
Vol 62 (4) ◽  
pp. 1062-1073 ◽  
Author(s):  
Sergio Pantano ◽  
Alessandro Marcello ◽  
Aldo Ferrari ◽  
Daniele Gaudiosi ◽  
Arianna Sabò ◽  
...  
Keyword(s):  
Molecular Dynamics ◽  
Molecular Recognition ◽  
Molecular Dynamics Simulations ◽  
In Vivo Experiments ◽  
Dynamics Simulations ◽  
Hiv 1

scholarly journals Sialyllactose in Viral Membrane Gangliosides Is a Novel Molecular Recognition Pattern for Mature Dendritic Cell Capture of HIV-1

PLoS Biology ◽  
2012 ◽  
Vol 10 (4) ◽  
pp. e1001315 ◽  
Author(s):  
Nuria Izquierdo-Useros ◽  
Maier Lorizate ◽  
F.-Xabier Contreras ◽  
Maria T. Rodriguez-Plata ◽  
Bärbel Glass ◽  
...  
Keyword(s):  
Dendritic Cell ◽  
Molecular Recognition ◽  
Mature Dendritic Cell ◽  
Cell Capture ◽  
Viral Membrane ◽  
Recognition Pattern ◽  
Hiv 1

scholarly journals Molecular Recognition of Cyclic Urea HIV-1 Protease Inhibitors

1998 ◽  
Vol 273 (20) ◽  
pp. 12325-12331 ◽  
Author(s):  
Paul J. Ala ◽  
Richard J. DeLoskey ◽  
Edward E. Huston ◽  
Prabhakar K. Jadhav ◽  
Patrick Y. S. Lam ◽  
...  
Keyword(s):  
Molecular Recognition ◽  
Protease Inhibitors ◽  
Hiv 1
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