Tenascin immunoreactivity in cryptogenic fibrosing alveolitis

1995 ◽  
Vol 175 (4) ◽  
pp. 415-420 ◽  
Author(s):  
W. A. H. Wallace ◽  
S. E. M. Howie ◽  
D. Lamb ◽  
D. M. Salter
Keyword(s):  
Fibrosing Alveolitis ◽  
Cryptogenic Fibrosing Alveolitis

Different Distributions of Kinetically Apparent Molecular Varieties of α2-Macroglobulin in Health and in Patients with Cryptogenic Fibrosing Alveolitis

1981 ◽  
Vol 60 (3) ◽  
pp. 261-265
Author(s):  
R. M. Topping ◽  
A. H. Craven ◽  
Susan Whiting ◽  
B. G. Rigden ◽  
M. Turner-Warwick ◽  
...  
Keyword(s):  
Protein Separation ◽  
Proteinase Inhibitors ◽  
Adult Population ◽  
Kinetic Method ◽  
Binding Modes ◽  
Fibrosing Alveolitis ◽  
Cryptogenic Fibrosing Alveolitis ◽  
Α2 Macroglobulin ◽  
Molecular Interpretation ◽  
Proteinase Inhibition

1. Proteinase inhibitors have been studied in whole serum by using a kinetic method that avoids potentially damaging protein separation procedures. 2. The α2-macroglobulin of an individual can be allocated unambiguously into one of seven categories according to the binding of trypsin to inhibitor in two kinetically apparent binding modes (β- and α-modes). 3. The distribution of α2-macroglobulin β:α ratios in a healthy adult population is defined, and shown to be independent of sex and age. 4. The distribution of β: α ratios in a group of patients with cryptogenic fibrosing alveolitis was found to be significantly different (P < 0.005) from the normal distribution. 5. Changes in the β: α ratio were noted in five of six patients with cryptogenic fibrosing alveolitis after treatment, but on no occasion when two healthy subjects were assessed a total of nine times. 6. The molecular interpretation and the possible importance of altered proteinase inhibition in inflammation and fibrosis are discussed.

Exposure to Commonly Prescribed Drugs and the Etiology of Cryptogenic Fibrosing Alveolitis

1998 ◽  
Vol 157 (3) ◽  
pp. 743-747 ◽  
Author(s):  
RICHARD HUBBARD ◽  
ANDREA VENN ◽  
CHRIS SMITH ◽  
MARIE COOPER ◽  
IAN JOHNSTON ◽  
...  
Keyword(s):  
Fibrosing Alveolitis ◽  
Cryptogenic Fibrosing Alveolitis

Autoimmunity associated with cardiac, respiratory, and renal disease

2013 ◽  
pp. 201-212
Author(s):  
Gavin P Spickett
Keyword(s):  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Renal Disease ◽  
Rheumatic Fever ◽  
Respiratory Disease ◽  
Cardiac Disease ◽  
Interstitial Pneumonitis ◽  
Fibrosing Alveolitis ◽  
Cryptogenic Fibrosing Alveolitis ◽  
Alveolar Proteinosis

Cardiac disease 1: myocarditis and cardiomyopathy Cardiac disease 2: eosinophilic syndromes Cardiac disease 3: recurrent pericarditis and Dressler’s syndrome Cardiac disease 4: rheumatic fever Respiratory disease 1: idiopathic pulmonary fibrosis (cryptogenic fibrosing alveolitis) Respiratory disease 2: pulmonary alveolar proteinosis (PAP) Respiratory disease 3: lymphoid interstitial pneumonitis and sarcoidosis...

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