Morphologic changes in the granular convoluted tubule cells of the mouse submandibular gland following hypophysectomy and hormonal replacement

Odontology ◽  
2002 ◽  
Vol 90 (1) ◽  
pp. 27-34 ◽  
Author(s):  
Shingo Kurabuchi
Keyword(s):  
Submandibular Gland ◽  
Hormonal Replacement ◽  
Granular Convoluted Tubule ◽  
Tubule Cells ◽  
Morphologic Changes

scholarly journals Biologically active polypeptides in submandibular glands.

1980 ◽  
Vol 28 (8) ◽  
pp. 836-859 ◽  
Author(s):  
T Barka
Keyword(s):  
Submandibular Gland ◽  
Chemical Properties ◽  
Hormonal Control ◽  
Biologically Active ◽  
Control Synthesis ◽  
Submandibular Glands ◽  
Granular Convoluted Tubule ◽  
Tubule Cells

Since the discovery of kallikreins in the submandibular glands in 1963 by Werle and Roden, a great number of biologically active polypeptides has been purified from, or claimed to be present in, the submandibular of the mouse and of other species. In this review, available data on the occurrence, chemical properties, localization, hormonal control, synthesis, secretion, and possible physiologic roles of 25 biologically active factors in mouse submandibular gland are analyzed. In general, these factors are androgen dependent, but not affected by the sex genotype, and are localized in the granular convoluted tubule cells in the gland. They are secreted into the saliva, but are also found in the circulation. Their physiologic roles are largely unknown.

Morphological changes and EGF expression in the granular convoluted tubule cells of submandibular glands of Trypanosoma cruzi infected rats

2008 ◽  
Vol 40 (4) ◽  
pp. 293-298 ◽  
Author(s):  
A. Moreira ◽  
M.H. Napimoga ◽  
B.B. Benatti ◽  
G.A.B. Silva ◽  
D.B. Rocha-Rodrigues ◽  
...  
Keyword(s):  
Trypanosoma Cruzi ◽  
Morphological Changes ◽  
Submandibular Glands ◽  
Granular Convoluted Tubule ◽  
Tubule Cells

The lack of terminal tubule cells in the submandibular gland of mice deficient in submandibular gland protein C

2020 ◽  
Vol 381 (2) ◽  
pp. 229-237
Author(s):  
Hiroki Nakata ◽  
Jumpei Terakawa ◽  
Shin-ichi Horike ◽  
Takiko Daikoku ◽  
Shoichi Iseki
Keyword(s):  
Submandibular Gland ◽  
Protein C ◽  
Tubule Cells

scholarly journals Developmental distribution of microperoxisomes in the rat submandibular gland.

1978 ◽  
Vol 26 (11) ◽  
pp. 989-999 ◽  
Author(s):  
B A Mooradian ◽  
L S Cutler
Keyword(s):  
Postnatal Development ◽  
Submandibular Gland ◽  
Acinar Cell ◽  
Secretory Cell ◽  
Fold Increase ◽  
Duct Cells ◽  
Size Number ◽  
Tubule Cells ◽  
Prenatal And Postnatal Development ◽  
Rat Submandibular Gland

The present study investigated the size, number, and distribution of microperoxisomes (MP) during the prenatal and postnatal development of the rat submandibular gland (SMG). A three-fold increase in MP number per cell was observed in the cells of the rudiment from the 15th to the 16th day of gestation. The early secretory and striated duct cells contained about 9.0 MP. The number of MP per secretory cell decreased such that 3.5 MP were found in each mature acinar cell. In the striated duct cells, MP number progressively increased to 40.0. As the convoluted granular tubule cells (CGT) developed from striated duct cells there was an increase in MP number from 16.0 to 26.0/cell. At maturity, the convoluted granular tubule cells contained only 14.0 MP. Throughout development of the SMG, intercalated duct cells showed only rare MP. The data suggests that the number, size, and distribution of MP changes as a function of the particular path of differentiation followed by the various cells in the rat SMG.

scholarly journals LOCALIZATION OF PEROXIDASE ACTIVITY IN THE DEVELOPING SUBMANDIBULAR GLAND OF NORMAL AND ISOPROTERENOL-TREATED RATS

1972 ◽  
Vol 20 (11) ◽  
pp. 855-872 ◽  
Author(s):  
SHOHEI YAMASHINA ◽  
TIBOR BARKA
Keyword(s):  
Endoplasmic Reticulum ◽  
Enzyme Activity ◽  
Submandibular Gland ◽  
Peroxidase Activity ◽  
Secretory Granules ◽  
Acinar Cells ◽  
Chronic Administration ◽  
Secretory Material ◽  
Old Rats ◽  
Tubule Cells

The localization of peroxidase activity was studied in the developing submandibular gland of normal and isoproterenol-treated rats using a diaminobenzidine-H2O2 method. During postnatal development peroxidase activity was localized in the proacinar and acinar cells. The proacinar cells were characterized by the presence of polymorphic secretory granules that gave a strong peroxidase reaction, particularly in the glands of 1-day-old rats. In addition to the secretory granules, enzyme activity was demonstrated in the rough endoplasmic reticulum and nuclear envelope. The terminal tubule cells and duct cells were devoid of peroxidase activity. The secretory granules in the fully developed acinar cells revealed little or no enzyme activity. Isoproterenol stimulated the secretion of the peroxidase-positive granules from the proacinar cells. The stimulation was followed by a reaccumulation of peroxidase-positive secretory material. During this process enzyme activity was demonstrable in the Golgi complex. Isoproterenol had no effect on the terminal tubule cells. A less effective depletion of the secretory granules from the proacinar cells was seen after pilocarpine administration. Chronic administration of isoproterenol to 5-day-old rats led to an acceleration of the differentiation of acinar cells and to a hypertrophy of the gland, without significant change in the localization of peroxidase activity.

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