The anatomy of the nervous system of the hydrozoan jellyfish, Polyorchis penicillatus, as revealed by a monoclonal antibody

2001 ◽  
Vol 4 (2) ◽  
pp. 65-75 ◽  
Author(s):  
Yi-Chan Lin ◽  
Warren J. Gallin ◽  
Andrew N. Spencer
Keyword(s):  
Monoclonal Antibody ◽  
Nervous System ◽  
Polyorchis Penicillatus

Expression of N-CAM precedes neural induction in Pleurodeles waltl (urodele, amphibian)

Development ◽  
1989 ◽  
Vol 106 (4) ◽  
pp. 675-683 ◽  
Author(s):  
J.P. Saint-Jeannet ◽  
F. Foulquier ◽  
C. Goridis ◽  
A.M. Duprat
Keyword(s):  
Monoclonal Antibody ◽  
Nervous System ◽  
Xenopus Laevis ◽  
Neural Induction ◽  
Gastrula Stage ◽  
Pleurodeles Waltl ◽  
Early Gastrula

The appearance and localization of N-CAM during neural induction were studied in Pleurodeles waltl embryos and compared with recent contradictory results reported in Xenopus laevis. A monoclonal antibody raised against mouse N-CAM was used. In the nervous system of Pleurodeles, it recognized two glycoproteins of 180 and 140×10(3) M(r) which are the Pleurodeles equivalent of N-CAM-180 and -140. Using this probe for immunohistochemistry and immunocytochemistry, we showed that N-CAM was already expressed in presumptive ectoderm at the early gastrula stage. In late gastrula embryos, a slight increase in staining was observed in the neurectoderm, whereas the labelling persisted in the noninduced ectoderm. When induced ectodermal cells were isolated at the late gastrula stage and cultured in vitro up to 14 days, a faint polarized labelling of cells was observed initially. During differentiation, the staining increased and became progressively restricted to differentiating neurons.

A novel monoclonal antibody that recognizes human perivascular cells of the central nervous system under a specific immune reaction

2000 ◽  
Vol 20 (3) ◽  
pp. 216-220 ◽  
Author(s):  
Hideaki Yokoo ◽  
Koji Isoda ◽  
Mizuaki Sakura ◽  
Atsushi Sasaki ◽  
Junko Hirato ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Monoclonal Antibody ◽  
Nervous System ◽  
Immune Reaction ◽  
Perivascular Cells ◽  
The Central Nervous System

Interleukin 6 in Cerebrospinal Fluid of Patients with Meningitis is not a Useful Diagnostic Marker in the Differential Diagnosis of Meningitis

1997 ◽  
Vol 34 (2) ◽  
pp. 165-169 ◽  
Author(s):  
L F López-Cortés ◽  
M Cruz-Ruiz ◽  
J Gómez-Mateos ◽  
D Jiménez-Hernández ◽  
P Viciana-Fernández ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Monoclonal Antibody ◽  
Cerebrospinal Fluid ◽  
Nervous System ◽  
Differential Diagnosis ◽  
Interleukin 6 ◽  
Diagnostic Marker ◽  
Neurological Diseases ◽  
Central Nervous System Infections ◽  
Pyogenic Meningitis

We assayed interleukin 6 (IL-6) concentrations in cerebrospinal fluid (CSF) from patients affected by meningitis of different aetiologies, and verified whether IL-6 can be used as a diagnostic marker in the differential diagnosis of meningitis. We used a monoclonal antibody enzyme immunoassay to test 98 CSF samples classified as pyogenic (15), viral (15), self-resolving aseptic meningitis (20), other infectious meningitis (9), neoplastic (4) and normal CSF from patients with (20) and without (15) non-infectious neurological diseases. CSF IL-6 concentrations were increased in pyogenic meningitis (100%) and in more than 50% of viral and other subarachnoid space infections, and rarely in patients without central nervous system infections. Though patients affected by pyogenic meningitis showed the highest levels of CSF IL-6, only a cut-off point ≥10000 pg/mL was able to discriminate pyogenic meningitis from those of other aetiologies with a specificity ≥94% and a positive predictive value of ≥0·75 but the sensitivity was ≤60%. Therefore, CSF IL-6 concentration is not a good diagnostic marker in the differential diagnosis of meningitis.

Production and Characterization of a Monoclonal Antibody to Human Nervous System-Specific γγ Enolase

1983 ◽  
Vol 93 (5) ◽  
pp. 1457-1460 ◽  
Author(s):  
Tomohiko HAYANO ◽  
Kanefusa KATO ◽  
Atsuko SHIMIZU ◽  
Yutaka ARIYOSHI ◽  
Yukio YAMADA ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Nervous System ◽  
Human Nervous System

Distribution of Thy-1 in the avian nervous system: Immunohistochemical and absorption analyses with a monoclonal antibody

1986 ◽  
Vol 398 (1) ◽  
pp. 91-105 ◽  
Author(s):  
Catriona M. Sinclair ◽  
Perry F. Bartlett ◽  
David I. Greig ◽  
Peter L. Jeffrey
Keyword(s):  
Monoclonal Antibody ◽  
Nervous System
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