Photodynamic Therapy (PDT) of Gastrointestinal Tumours: A New Light Delivery System

1998 ◽  
Vol 13 (2) ◽  
pp. 137-142 ◽  
Author(s):  
J.V.E. Roche ◽  
C. Whitehurst ◽  
P. Watt ◽  
J.V. Moore ◽  
N. Krasner
Keyword(s):  
Photodynamic Therapy ◽  
Delivery System ◽  
Light Delivery ◽  
Gastrointestinal Tumours

Diverse optical characteristic of the prostate and light delivery system: implications for computer modelling of prostatic photodynamic therapy

2005 ◽  
Vol 95 (9) ◽  
pp. 1237-1244 ◽  
Author(s):  
Jerzy Jankun ◽  
Rick W. Keck ◽  
Ewa Skrzypczak-Jankun ◽  
Lothar Lilge ◽  
Steven H. Selman
Keyword(s):  
Photodynamic Therapy ◽  
Delivery System ◽  
Optical Characteristic ◽  
Computer Modelling ◽  
Light Delivery

An interstitial light delivery system for photodynamic therapy within the liver

1993 ◽  
Vol 8 (4) ◽  
pp. 253-257 ◽  
Author(s):  
S. F. Purkiss ◽  
R. Dean ◽  
J. T. Allardice ◽  
M. Grahn ◽  
N. S. Williams
Keyword(s):  
Photodynamic Therapy ◽  
Delivery System ◽  
Light Delivery

Design and construction of a light-delivery system for photodynamic therapy

1999 ◽  
Vol 26 (8) ◽  
pp. 1552-1558 ◽  
Author(s):  
David A. Bellnier ◽  
Leroy M. Wood ◽  
William R. Potter ◽  
Kenneth R. Weishaupt ◽  
Allan R. Oseroff
Keyword(s):  
Photodynamic Therapy ◽  
Delivery System ◽  
Light Delivery ◽  
Design And Construction

A Telemetric light delivery system for metronomic photodynamic therapy (mPDT) in rats

2010 ◽  
Vol 3 (5-6) ◽  
pp. 347-355 ◽  
Author(s):  
Floor van Zaane ◽  
Devendiran Subbaiyan ◽  
Angelique van der Ploeg-van den Heuvel ◽  
Henriëtte S. de Bruijn ◽  
Eduardo Margallo Balbas ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Delivery System ◽  
Light Delivery

Design of a High Yielding Photonic Light Delivery System to be Used in Photodynamic Therapy for Esophageal Cancer, With Microwave Antenna Imprinted Balloon Catheter for Oxygen Enhancement

2006 ◽  
Author(s):  
Amaranath Premasiri ◽  
Gemunu Happawana ◽  
Gary Evans ◽  
Arye Rosen
Keyword(s):  
Esophageal Cancer ◽  
Photodynamic Therapy ◽  
Delivery System ◽  
Low Cost ◽  
Balloon Catheter ◽  
Treatment Method ◽  
Microwave Antenna ◽  
Semiconductor Diode ◽  
Invasive Treatment ◽  
Light Delivery

Photodynamic therapy (PDT) is a minimally invasive treatment with high effectiveness in the management of cancer of the upper gastrointestinal tract. A higher mortality rate associated with surgery and the higher morbidity in the older age group both make PDT a better treatment method for the treatment of esophageal cancer [1–3]. However, limitations in the best docimetry protocols performance of PDT are due to ineffectiveness of the light delivery and in the unavailability of sufficient oxygen required for singlet oxygen generation to bring cellular death [4–7]. The Introduction of an inexpensive high power semiconductor diode lasers for the light delivery system makes PDT efficient, low cost and portable [8–10]. However, the metallic water cooling systems used in the existing semiconductor cooling designs make those systems non-flexible and cumbersome in size [9].

scholarly journals Optical Characterization of an Intra-Arterial Light and Drug Delivery System for Photodynamic Therapy of Atherosclerotic Plaque

2020 ◽  
Vol 10 (12) ◽  
pp. 4304
Author(s):  
Matthieu Zellweger ◽  
Ying Xiao ◽  
Manish Jain ◽  
Marie-Noëlle Giraud ◽  
Andreas Pitzschke ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Photodynamic Therapy ◽  
Drug Delivery System ◽  
Delivery System ◽  
Planar Imaging ◽  
Light Dosimetry ◽  
Light Delivery ◽  
The Many ◽  
Light Diffuser

Although the versatility of photodynamic therapy (PDT) is well established, the technical aspects of light delivery systems vary significantly depending on the targeted organ. This article describes the optical properties of a light and drug delivery system (catheter and light diffuser) suitable for intra-arterial PDT by using a planar imaging goniometer to measure the full radiance longitudinal and angular profiles at the surface of the diffuser at 652 nm. The results show that the system emits almost Lambertian and “top hat” profiles, an interesting feature to determine the light dosimetry in the many vascular applications of PDT.

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