Modification of respiratory function parameters in patients with severe Parkinson's disease

2002 ◽  
Vol 23 (0) ◽  
pp. s69-s70 ◽  
Author(s):  
M.F. De Pandis ◽  
A. Starace ◽  
F. Stefanelli ◽  
P. Marruzzo ◽  
I. Meoli ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Respiratory Function

Effect of aging and dopaminomimetic therapy on mitochondrial respiratory function in Parkinson's disease

1992 ◽  
Vol 7 (3) ◽  
pp. 228-231 ◽  
Author(s):  
Daniele Bravi ◽  
Jeffrey J. Anderson ◽  
Fiorenzo Dagani ◽  
Thomas L. Davis ◽  
Rosaria Ferrari ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Respiratory Function ◽  
Mitochondrial Respiratory

scholarly journals Respiratory Function of Patients with Parkinson's Disease and Movement Therapy.

1992 ◽  
Vol 7 (1) ◽  
pp. 15-20
Author(s):  
Kenji IZUMI ◽  
Satoshi MIYASHITA ◽  
Seiji SANO ◽  
Kazusuke DOI
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Respiratory Function ◽  
Movement Therapy

Respiratory Function in Parkinson's Subjects Exhibiting a Perceptible Speech Deficit

1989 ◽  
Vol 54 (4) ◽  
pp. 610-626 ◽  
Author(s):  
Bruce E. Murdoch ◽  
Helen J. Chenery ◽  
Simon Bowler ◽  
John C. L. Ingram
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Chest Wall ◽  
Respiratory Function ◽  
Neuromuscular Function ◽  
Lung Volumes ◽  
Normal Limits ◽  
Essentially Normal ◽  
Syllable Repetition ◽  
Age And Sex

The respiratory abilities of a group of 19 speech-disordered subjects with idiopathic Parkinson's disease were assessed using both spirometric and kinematic techniques and compared to those of a group of 19 nonneurologically impaired controls matched for age and sex. Results of the spirometric assessment showed that only a minority of the Parkinson's subjects had lung volumes and capacities outside normal limits. Consequently in the majority of eases, the speech disorder could not be related to any abnormality in lung function determined spirometrically. Chest wall dynamics during both conversation and reading were essentially normal in all cases. Approximately half of the Parkinson's subjects, however, exhibited irregularities in their chest wall movements while performing vowel prolongation and syllable repetition tasks. The same irregularities were not present in the chest wall movements exhibited by the control subjects, suggesting that their presence was in some way related to the Parkinson's disease. Results are discussed in terms of the effects of Parkinson's disease on neuromuscular function.

Parkinson's disease: An investigation of exercise capacity, respiratory function, and gait

1997 ◽  
Vol 78 (2) ◽  
pp. 199-207 ◽  
Author(s):  
Colleen G. Canning ◽  
Jennifer A. Alison ◽  
Natalie E. Allen ◽  
Herbert Groeller
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Exercise Capacity ◽  
Respiratory Function

Respiratory Function And Ventilatory Responses In Subjects With Parkinson's Disease

2011 ◽  
Author(s):  
Elizabeth M. Veitch ◽  
Hugh Giddings ◽  
Leigh Seccombe ◽  
Peter Rogers ◽  
Alistair Corbett
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Respiratory Function ◽  
Ventilatory Responses

scholarly journals The Role of the Diaphragm in Postural Stability and Visceral Function in Parkinson’s Disease

2021 ◽  
Vol 13 ◽  
Author(s):  
Xin Yu ◽  
Hong-ying Jiang ◽  
Chen-xi Zhang ◽  
Zhao-hui Jin ◽  
Lei Gao ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Respiratory Function ◽  
Postural Stability ◽  
Rating Scale ◽  
Lasso Regression ◽  
Quiet Breathing ◽  
Diaphragmatic Function ◽  
Diaphragm Function

Background: In normal subjects, the diaphragm plays a key functional role in postural stability, articulation, respiration, defecation, and urination.Objectives: The aim of this study was to investigate the role of the diaphragm in postural stability and visceral function in patients with Parkinson’s disease (PD) and to compare the diaphragm function by gender, Hoehn and Yahr (H&Y) staging, and motor subtypes.Methods: In total, 79 patients were enrolled in this cross-sectional study. The severity of the disease was assessed by the Movement Disorder Society-Unified Parkinson’s Disease Rating Scale III and by H&Y staging. Postural stability was quantitatively recorded, and respiratory function was evaluated by spirometry. Several scales were used to evaluate visceral function in patients with PD. In addition, diaphragm ultrasound was used to measure the excursion, contraction velocity, and thickness of the diaphragm during quiet breathing, deep breathing, and the sniff test. Significant features were selected by the least absolute shrinkage and selection operator (LASSO) regression and fitted in the multivariate linear regression and Pearson’s correlation analysis.Results: Diaphragm thickness and excursion during quiet breathing were significantly different between men and women and between H&Y stage 1–2 and stage 2.5–3, whereas the diaphragm function was not influenced by motor subtypes. It was shown that the diaphragmatic function was significantly correlated with postural stability, voice function, respiratory function, constipation, and urological function to varying degrees in patients with PD.Conclusion: The diaphragmatic function is associated with dysfunction in PD although it remains unclear as to whether the observed changes in the diaphragm are primary or secondary.

scholarly journals The influence of levodopa on respiratory function in Parkinson's disease patients: a systematic review and meta-analysis

2021 ◽  
Vol 10 (14) ◽  
pp. e457101422262
Author(s):  
Francisco José Silva Ferreira ◽  
Paulo Eduardo Gonçalves ◽  
Alice Santos Lima ◽  
Diogo Costa Garção
Keyword(s):  
Systematic Review ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Lung Function ◽  
Respiratory Function ◽  
Data Extraction ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Random Effects Model ◽  
Exclusion Criteria

There is no consensus in the literature about the influence of levodopa on respiratory disorders, which are the main cause of death in Parkinson’s disease patients. Thus, the aim of this study was to conduct a systematic review and meta-analysis to assess the influence of levodopa on lung function in patients with Parkinson’s disease. A systematic search was performed in the MEDLINE-PubMed, Lilacs, IEEE Xplore Digital Library and Cochrane Library databases, until July 2020. Eligibility, screening, data extraction and quality assessment of the studies found were conducted independently by a minimum of two reviewers. The meta-analysis was made using RevMan 5, using standardized difference of means (SDM) with the random effects model and 95% confidence interval. The presence of heterogeneity was evaluated through the percentage of i². In total, 78 studies were identified; of these,7 were included in the review and meta-analysis after considering the inclusion and exclusion criteria. By comparing the 'on' and 'off' levodopa states, in the outcomes of interest found in the included studies, the following results were obtained in the meta-analysis: FVC (SMD of 0.12, p = 0.41); FEV1 (SMD of 0.10, p = 0.47); PEF (SMD of -0.00, p = 0.99); FEV1/FVC (SMD 0.04, p = 0.76). The conducted study suggested that there was no influence of levodopa treatment on any of the pulmonary variables assessed in patients with Parkinson’s disease.    

scholarly journals Using the spirometry to indicate respiratory exercises for elderly with Parkinson’s disease

2018 ◽  
Vol 31 (0) ◽  
Author(s):  
Daniela Guimarães ◽  
Gabriel Duarte ◽  
Karen Trippo ◽  
Graziella Furtado ◽  
Jamary Oliveira Filho ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Respiratory Function ◽  
Respiratory Muscles ◽  
Cross Sectional Study ◽  
Yahr Stage ◽  
Cross Sectional ◽  
Respiratory Dysfunction ◽  
Predicted Values ◽  
Respiratory Exercises

Abstract Introduction: Respiratory dysfunction is the main cause of death in Parkinson's disease (PD) patients and bronchoaspiration pneumonia is the most common clinical respiratory complication. Objective: To assess respiratory function of elderly with PD in mild to moderate phase of the disease. Methods: A cross-sectional study was carried. Elderly in 2 to 3 PD Hoehn & Yahr stage have participated. A single researcher has evaluated maximal inspiratory pressure (MIP), maximal expiratory pressure (MEP), thoracoabdominal amplitude, forced vital capacity (FVC) and expiratory volume in the first second (FEV1). Results: Sixty elderly have participated and their all spirometry and manovacuometry parameters presented significant differences (p < 0.05) comparing with predicted values, except for FVC (p = 0.25). Only umbilical level did not reach normal values on cirtometry parameters. Patients classified as a restrictive disorder presented significant decrease in thoracic expandability. However the participants classified as an obstructive disorder showed significant decrease in expiratory muscle strength and peak expiratory flows. Conclusion: Elderly in mild or moderate phase of PD presented reduction in respiratory parameters. Spirometry showed to be an important tool to evaluate respiratory function and to indicate the modality of respiratory exercise. Our results suggest the indication of thoracic flexibility exercises for patient with PD classified as restrictive disorder and strength exercise of respiratory muscles for those classified as obstructive disorder.

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