Cytoplasmic Transfer of Platelet mtDNA from Elderly Patients with Parkinson's Disease to mtDNA-less HeLa Cells Restores Complete Mitochondrial Respiratory Function

2001 ◽  
Vol 280 (1) ◽  
pp. 265-273 ◽  
Author(s):  
Yuko Aomi ◽  
Chu-Shih Chen ◽  
Kazuto Nakada ◽  
Sayaka Ito ◽  
Kotoyo Isobe ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Elderly Patients ◽  
Hela Cells ◽  
Respiratory Function ◽  
Cytoplasmic Transfer ◽  
Mitochondrial Respiratory

Effect of aging and dopaminomimetic therapy on mitochondrial respiratory function in Parkinson's disease

1992 ◽  
Vol 7 (3) ◽  
pp. 228-231 ◽  
Author(s):  
Daniele Bravi ◽  
Jeffrey J. Anderson ◽  
Fiorenzo Dagani ◽  
Thomas L. Davis ◽  
Rosaria Ferrari ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Respiratory Function ◽  
Mitochondrial Respiratory

Mitochondrial respiratory chain disorganization in Parkinson's disease-relevant PINK1 and DJ1 mutants

2017 ◽  
Vol 109 ◽  
pp. 101-105 ◽  
Author(s):  
Irene Lopez-Fabuel ◽  
Lucia Martin-Martin ◽  
Monica Resch-Beusher ◽  
Garikoitz Azkona ◽  
Rosario Sanchez-Pernaute ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Respiratory Chain ◽  
Mitochondrial Respiratory Chain ◽  
Mitochondrial Respiratory

An 18-month prospective cohort study of functional outcome of delirium in elderly patients: activities of daily living

2006 ◽  
Vol 18 (4) ◽  
pp. 681-700 ◽  
Author(s):  
Stephen Vida ◽  
Guillaume Galbaud du Fort ◽  
Ritsuko Kakuma ◽  
Louise Arsenault ◽  
Robert W. Platt ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cohort Study ◽  
Elderly Patients ◽  
Activities Of Daily Living ◽  
Functional Outcome ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Daily Living ◽  
Medical Problems

Objectives: To examine delirium, chronic medical problems and sociodemographic factors as predictors of activities of daily living (ADL), basic ADL (BADL) and instrumental ADL (IADL).Methods: A prospective cohort study of four groups of elderly patients examined in the emergency department (ED): those with delirium, dementia, neither, and both. All were aged 66 years or older and living at home. Delirium was assessed with the Confusion Assessment Method and dementia with the Informant Questionnaire on Cognitive Decline in the Elderly. Demographic variables and chronic medical problems were ascertained with questionnaires. Outcome was ADL at 6, 12 and 18 months, measured with the ADL subscale of the Older Americans Resources and Services instrument.Results: Univariate analyses suggested significantly poorer ADL, particularly IADL, at 18 months in the delirium versus the non-delirium group, in the absence of dementia only. Statistically significant independent predictors of poorer ADL at 18 months in the non-dementia groups were poorer initial ADL, stroke, Parkinson's disease, hypertension and female sex. Independent predictors of poorer BADL at 18 months in the non-dementia groups were poorer initial BADL, Parkinson's disease, stroke, cancer, colds/sinusitis/laryngitis, female sex and hypertension. Independent predictors of poorer IADL at 18 months in the non-dementia groups were poorer initial IADL, stroke, never-married status, colds/sinusitis/laryngitis, arthritis and hypertension, with Parkinson's disease showing a non-significant but numerically large regression coefficient.Conclusion: Rather than finding delirium to be a predictor of poorer functional outcome among survivors, we found an interaction between delirium and dementia and several plausible confounders, primarily chronic medical problems, although we cannot rule out the effect of misclassification or survivor bias.

scholarly journals Immortalized Parkinson's disease lymphocytes have enhanced mitochondrial respiratory activity

2016 ◽  
Vol 9 (11) ◽  
pp. 1295-1305 ◽  
Author(s):  
Sarah J. Annesley ◽  
Sui T. Lay ◽  
Shawn W. De Piazza ◽  
Oana Sanislav ◽  
Eleanor Hammersley ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Respiratory Activity ◽  
Mitochondrial Respiratory Activity ◽  
Mitochondrial Respiratory

scholarly journals How Should Pergolide Treatment be Initiated in Elderly Patients with Parkinson's Disease?

1997 ◽  
Vol 26 (suppl 1) ◽  
pp. P16-P16
Author(s):  
R.J. Meara ◽  
T.P. Cassidy ◽  
A. Dunn ◽  
J. Hindle ◽  
I.M. Huggett ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Elderly Patients
Sign in / Sign up

Export Citation Format

Share Document