Association of estrogen receptor β (ESR2) gene polymorphism with blood pressure

2000 ◽  
Vol 45 (6) ◽  
pp. 327-330 ◽  
Author(s):  
S. Ogawa ◽  
M. Emi ◽  
M. Shiraki ◽  
T. Hosoi ◽  
Y. Ouchi ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Estrogen Receptor ◽  
Gene Polymorphism ◽  
Estrogen Receptor Β ◽  
Esr2 Gene

scholarly journals The Association of Estrogen Receptor-β Gene Variation With Salt-Sensitive Blood Pressure

2017 ◽  
Vol 102 (11) ◽  
pp. 4124-4135 ◽  
Author(s):  
Worapaka Manosroi ◽  
Jia Wei Tan ◽  
Chevon M Rariy ◽  
Bei Sun ◽  
Mark O Goodarzi ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Estrogen Receptor ◽  
Estrogen Receptor Β ◽  
Gene Variation

scholarly journals Polymorphisms and Haplotypes of the Estrogen Receptor-β Gene (ESR2) and Cardiovascular Disease in Men and Women

2007 ◽  
Vol 53 (10) ◽  
pp. 1749-1756 ◽  
Author(s):  
Kathryn M Rexrode ◽  
Paul M Ridker ◽  
Hillary H Hegener ◽  
Julie E Buring ◽  
JoAnn E Manson ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Estrogen Receptor ◽  
Ischemic Stroke ◽  
White Women ◽  
White Men ◽  
Estrogen Receptor Α ◽  
Estrogen Receptor Β ◽  
Health Study ◽  
Increased Risk ◽  
Esr2 Gene

Abstract Background: Cohort studies suggest an association between variation in the estrogen receptor-α gene (ESR1) and cardiovascular disease (CVD), but data are lacking for the effect of variation in the estrogen receptor-β gene (ESR2). Methods: Three polymorphisms of the ESR2 gene, and their associated haplotypes, were evaluated in 296 white women from the Women’s Health Study and 566 white men from the Physicians’ Health Study who developed CVD [myocardial infarction (MI) or ischemic stroke], each matched 1:1 to a member of the cohort study who remained free from CVD. Blood samples and cardiovascular risk information were collected at baseline. Results: Women, but not men, who developed CVD or MI, but not ischemic stroke, were more likely to have the rs1271572 polymorphism variant T allele (P = 0.05 and 0.02) and less likely to have the rs1256049 polymorphism variant A allele (P = 0.003 and 0.004). No associations were observed for rs4986938. In conditional logistic multivariate regression, the rs1271572 variant was associated with increased odds of CVD [odds ratio (OR) = 1.49, 95% CI: 1.10–2.01] and MI (OR = 1.46, 95% CI: 0.96–2.23), whereas the rs1256049 variant was associated with decreased odds of CVD (OR = 0.37, 95% CI: 0.17–0.79) and MI (OR = 0.25, 95% CI: 0.09–0.73) in women. A common haplotype that included the rs1271572 variant was associated with a 7-fold increased risk of MI in women. Conclusions: Two tightly linked polymorphisms of ESR2 were associated with risk of CVD, particularly MI, in women but not men. Additional studies of ESR2 genetic variation and risk of CVD are warranted.

scholarly journals Polymorphisms in the Estrogen Receptor β (ESR2) Gene Are Associated with Bone Mineral Density in Caucasian Men and Women

2005 ◽  
Vol 90 (11) ◽  
pp. 5921-5927 ◽  
Author(s):  
Shoji Ichikawa ◽  
Daniel L. Koller ◽  
Munro Peacock ◽  
Michelle L. Johnson ◽  
Dongbing Lai ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Estrogen Receptor ◽  
Bone Mineral ◽  
Estrogen Receptor Β ◽  
Mineral Density ◽  
Men And Women ◽  
Caucasian Men ◽  
Esr2 Gene

Estrogen receptor-β gene polymorphism and colorectal cancer risk: Effect modified by body mass index and isoflavone intake

2012 ◽  
Vol 132 (4) ◽  
pp. 951-958 ◽  
Author(s):  
Naoko Honma ◽  
Ken Yamamoto ◽  
Keizo Ohnaka ◽  
Makiko Morita ◽  
Kengo Toyomura ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Body Mass Index ◽  
Estrogen Receptor ◽  
Cancer Risk ◽  
Gene Polymorphism ◽  
Body Mass ◽  
Estrogen Receptor Β ◽  
Colorectal Cancer Risk ◽  
Risk Effect

Association of Estrogen Receptor β Gene Polymorphism with Bone Mineral Density

2000 ◽  
Vol 269 (2) ◽  
pp. 537-541 ◽  
Author(s):  
Sumito Ogawa ◽  
Takayuki Hosoi ◽  
Masataka Shiraki ◽  
Hajime Orimo ◽  
Mitsuru Emi ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Estrogen Receptor ◽  
Gene Polymorphism ◽  
Bone Mineral ◽  
Estrogen Receptor Β ◽  
Mineral Density

scholarly journals Association Study Using Single Nucleotide Polymorphisms in the Estrogen Receptor β (ESR2) Gene for Preeclampsia

2004 ◽  
Vol 27 (12) ◽  
pp. 903-909 ◽  
Author(s):  
Aya MARUYAMA ◽  
Tomohiro NAKAYAMA ◽  
Naoyuki SATO ◽  
Yoshihiro MIZUTANI ◽  
Kiyohide FURUYA ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Single Nucleotide Polymorphisms ◽  
Association Study ◽  
Estrogen Receptor Β ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Esr2 Gene

1625: Role of Estrogen Receptor β in the Regulation of Sexual Behavior in Male Mice

2004 ◽  
Vol 171 (4S) ◽  
pp. 429-429
Author(s):  
Masayoshi Nomura ◽  
Naohiro Fujimoto ◽  
Donald W. Pfaff ◽  
Sonoko Ogawa ◽  
Tetsuro Matsumoto
Keyword(s):  
Estrogen Receptor ◽  
Sexual Behavior ◽  
Estrogen Receptor Β ◽  
Male Mice

1322: The Expression of Estrogen Receptor α and Estrogen Receptor β in the Human Fetal Prostate

2004 ◽  
Vol 171 (4S) ◽  
pp. 348-348
Author(s):  
Ellen Shapiro ◽  
Hongying Huang ◽  
Rachael R. Mash ◽  
Eliza Ng ◽  
Deborah E. McFadden ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Estrogen Receptor Α ◽  
Estrogen Receptor Β
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