Lundh meal: a single non-invasive challenge test for evaluation of exocrine and endocrine pancreatic function in cystic fibrosis patients

1999 ◽  
Vol 29 (3) ◽  
pp. 114-116 ◽  
Author(s):  
A. Augarten ◽  
L. Dubenbaum ◽  
Y. Yahav ◽  
D. Katznelson ◽  
A. Szeinberg ◽  
...  
Pancreatology ◽  
2010 ◽  
Vol 10 (2-3) ◽  
pp. 129-133 ◽  
Author(s):  
Luca Frulloni ◽  
Chiara Scattolini ◽  
Anna Maria Katsotourchi ◽  
Antonio Amodio ◽  
Armando Gabbrielli ◽  
...  

2018 ◽  
Vol 5 ◽  
Author(s):  
Cibele Zanardi Esteves ◽  
Letícia de Aguiar Dias ◽  
Estela de Oliveira Lima ◽  
Diogo Noin de Oliveira ◽  
Carlos Fernando Odir Rodrigues Melo ◽  
...  

2021 ◽  
pp. 39-48
Author(s):  
Yumiko Vreeburg ◽  
Laura van Vugt ◽  
Sabrina Simonnet ◽  
Daphne Valk ◽  
Gus Schardijn ◽  
...  

Objectives: Early microvascular damage and dysfunction are clinically mirrored in Raynaud’s phenomenon (RP). Currently, nailfold capillaroscopy (NC) is applied to differentiate between primary RP (PRP) and secondary RP (PRP), associated with connective tissue disease. However, abnormal morphology can also be caused due to age-related changes and cardiovascular disease. Thermography (TG) is a non-invasive technique which enables quantification of cutaneous vascular function. An approach using both NC and TG could improve the differentiation between PRP and SRP. Methods: Thirty RP patients (PRP, n = 21; SRP, n = 9) underwent nailfold capillaroscopy and thermography. Morphologic features were scored and patients were categorized according to the guidelines of EULAR Study group on Microcirculation in Rheumatic Diseases. TG of the hand was performed before, directly and ten minutes after a cold challenge test. Baseline images and rewarming curves were analyzed. Results: Capillary abnormalities with NC were found in all SRP patients (9/9) and in 48% (10/21) of PRP patients. Out of 10 PRP patients with altered capillary morphology, 9 (90%) had a cardiovascular disease. For all patients mean temperature was significantly higher 10 minutes after cold induction than before (p < 0,01). The gradient of the rewarming curve was significantly lower in patients with SRP compared to PRP patients (p = 0.015). Conclusions: Nailfold capillaroscopy and thermography can reliably be used to measure microvascular damage and dysfunction. Additional thermography can assist in differentiating between PRP and SRP, especially in elderly patients or in presence of a cardiovascular disease. Keywords: Raynaud’s phenomenon; Nailfold capillaroscopy; Thermography


2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Antonella Tosco ◽  
Angela Sepe ◽  
Alice Castaldo ◽  
Andrea Catzola ◽  
Chiara Cimbalo ◽  
...  

2019 ◽  
Vol 64 (1) ◽  
pp. 24-28 ◽  
Author(s):  
A. V. Kozlov ◽  
O. A. Gusyakova ◽  
A. A. Ereshchenko ◽  
A. V. Khaliulin

The review presents the pathobiochemical and molecular mechanisms of sputum formation in patients with cystic fibrosis associated with the pathophysiological features of the disease. Statistical data on the prevalence of this pathology in the world and in the Russian Federation are presented. The mechanisms of sputum formation and disorders of the mucociliary apparatus, leading to the accumulation of viscous bronchopulmonary secret in cystic fibrosis, are considered. The principles of the relationship between the rheological properties of sputum and the formation of inflammation in the lungs with the addition of a concomitant specific microflora in the bronchopulmonary system in patients with cystic fibrosis are presented. Describes the opportunities for biochemical studies of sputum of patients with this pathology: determining the activity of enzymes (myeloperoxidase), the content of proteinase inhibitors (α2-macroglobulin and α1-antitrypsin) and proinflammatory cytokines (IL-8 and TNFa), concentrations of iron and ferriferous proteins (lactoferrin and ferritin), which makes biochemical studies of sputum available, non-invasive, quick and cost-effective method of diagnosis, which can be widely used as an auxiliary laboratory method and makes it possible to use these metabolites as diagnostic markers to assess the severity of inflammation and infection of the lower respiratory tract and predict the development of respiratory complications in patients with cystic fibrosis.


2011 ◽  
Vol 140 (5) ◽  
pp. S-545
Author(s):  
Bimaljit S. Sandhu ◽  
Rajesh Gupta ◽  
D. Nageshwar Reddy ◽  
Ravi Vachhani ◽  
Doumit BouHaidar ◽  
...  

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