A 13 C-urea breath test in children with Helicobacter pylori infection: assessment of eradication therapy and follow-up after treatment

2001 ◽  
Vol 36 (9) ◽  
pp. 606-611 ◽  
Author(s):  
Norikazu Yoshimura ◽  
Hitoshi Tajiri ◽  
Atsushi Sawada ◽  
Kosuke Kozaiwa ◽  
Shinobu Ida ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Breath Test ◽  
Eradication Therapy ◽  
Urea Breath Test ◽  
Helicobacter Pylori Infection

A simplified 13C-urea breath test in children with Helicobacter pylori infection: Assessment of eradication therapy and follow-up after treatment

2001 ◽  
Vol 120 (5) ◽  
pp. A579 ◽  
Author(s):  
Atsushi Sawada ◽  
Hitoshi Tajiri ◽  
Norikazu Yoshimura ◽  
Kosuke Kozaiwa ◽  
Shinobu Ida ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Breath Test ◽  
Eradication Therapy ◽  
Urea Breath Test ◽  
Helicobacter Pylori Infection ◽  
13C Urea Breath Test

THE EFFICACY OF THE BISMUTH-CONTAINING QUADRUPLE REGIMEN IN HELICOBACTER PYLORI INFETION

2017 ◽  
pp. 29-34
Author(s):  
Thi Khanh Tuong Tran ◽  
Quoc Bao Vu
Keyword(s):  
Helicobacter Pylori ◽  
Side Effects ◽  
Breath Test ◽  
Eradication Therapy ◽  
Urea Breath Test ◽  
Helicobacter Pylori Infection ◽  
Adherence Rate ◽  
Helicobacter Pylori Eradication ◽  
Colloidal Bismuth Subcitrate ◽  
Helicobacter Pylori Eradication Therapy

Background and Objectives: Bismuth-containing quadruple regimen is recommended as an first-line therapy in areas with high clarithromycin and metronidazole resistance as well as an option for patients who have previously failed to respond to Helicobacter pylori eradication therapy. There have been very few researches on the effectiveness of this regimen on Helicobacter pylori infection treatment in our country. The our study aimed to show the efficacy of Bismuth-based therapy for the treatment of Helicobacter pylori infection. Patients and Methods: The study was carried out on 196 patients with Helicobacter pylori infection. All of patients received a quadruple therapy consisted of Rapeprazole 20 mg bid, Colloidal bismuth subcitrate 120mg qid, Tetracycline 500mg qid and Metronidazole 500mg tid for 14 days. The diagnosis of Helicobacter Pylori infection was performed by Clotest or C13 urea-breath test. Four to eight weeks after completion of therapy, Helicobacter pylori status was rechecked by Clotest or C13 urea-breath test. Results: A total of 196 patients with Helicobacter pylori infection were recruited. The eradication rates of the Bismuth-containing quadruple regimen overall, fornaïve,previously failed to respond to Helicobacter pylori eradication therapy on intention to treat (ITT) and per-protocol (PP) analysis were 97.4-97.3%; 98.3-98.1% and 96.3-96.2%. Side effects occurred in 80.5% of subjects. The common side effects were fatigue, anorexia and nausea. The compliancerate was 98.4%. Conclusions: Bismuth-containing quadruple regimen achieved very highe radication rates. Side effects were common but not serious. The medication adherence rate was high. Key words: Bismuth-containing quadruple regimen, eradication, Helicobacter pylori infection

scholarly journals Noninvasive Diagnostic Tests for Helicobacter Pylori Infection in Children

2005 ◽  
Vol 19 (7) ◽  
pp. 433-439 ◽  
Author(s):  
Sibylle Koletzko
Keyword(s):  
Helicobacter Pylori ◽  
Breath Test ◽  
Clinical Decision Making ◽  
Age Groups ◽  
Eradication Therapy ◽  
High Sensitivity ◽  
Urea Breath Test ◽  
Helicobacter Pylori Infection ◽  
Noninvasive Test ◽  
H Pylori

Noninvasive tests can be used for the initial diagnosis of Helicobacter pylori infection and to monitor the success of eradication therapy. In populations with a low prevalence of H pylori infection (children living in North America and Europe), a high sensitivity is required to make the test valuable for clinical practice. The13C-urea breath test has been validated in children of different age groups in a significant number of infected and noninfected children in several countries and, thus far, is the only noninvasive test that fulfills sensitivity and specificity quality standards. In studies to date, enzyme immunoassays using monoclonal antibodies to detect H pylori antigen in stool provide excellent results, but the number of children tested, particularly post-treatment, is not sufficient to recommend the test. All other noninvasive stool tests or methods based on the detection of specific antibodies in serum, whole blood, urine or saliva have limited accuracy in comparison with the13C-urea breath test. Therefore, these tests cannot be recommended for clinical decision making in pediatric patients.

Effect of Fasting Subjects’ Posture on 13 C‐Urea Breath Test for Detection of Helicobacter pylori Infection

Helicobacter ◽  
1997 ◽  
Vol 2 (2) ◽  
pp. 82-85 ◽  
Author(s):  
Hiroto Miwa ◽  
Toshio Murai ◽  
Ryuichi Ohkura ◽  
Masato Kawabe ◽  
Hiroshi Tanaka ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Breath Test ◽  
Urea Breath Test ◽  
Helicobacter Pylori Infection
Sign in / Sign up

Export Citation Format

Share Document