Inferior vena cava indices determine volume load in minimal lesion nephrotic syndrome

2001 ◽  
Vol 16 (3) ◽  
pp. 251-255 ◽  
Author(s):  
Osman Dönmez ◽  
Sevgi Mir ◽  
Ruhi Özyürek ◽  
Alphan Cura ◽  
Caner Kabasakal
Keyword(s):  
Nephrotic Syndrome ◽  
Inferior Vena Cava ◽  
Inferior Vena ◽  
Vena Cava ◽  
Volume Load ◽  
Minimal Lesion Nephrotic Syndrome

scholarly journals Nephrotic Syndrome Due to Thrombosis of the Inferior Vena Cava and Renal Veins

1965 ◽  
Vol 41 (472) ◽  
pp. 88-93 ◽  
Author(s):  
T. J. Bayley ◽  
D. Heath ◽  
J. Hardwicke ◽  
A. G. W. Whitfield
Keyword(s):  
Nephrotic Syndrome ◽  
Inferior Vena Cava ◽  
Inferior Vena ◽  
Vena Cava ◽  
Renal Veins

scholarly journals Inferior Vena Cava Collapsibility Index: A Precise Non-invasive Tool for Evaluation of Edema in Children with Nephrotic Syndrome.

2021 ◽  
Author(s):  
Hanan El-Halaby ◽  
Ashraf Bakr ◽  
Mohamed El-Assmy ◽  
Hussein Abdelaziz Abdalla ◽  
Marwa Salem ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Inferior Vena Cava ◽  
Inferior Vena ◽  
Vena Cava ◽  
Fractional Excretion ◽  
Volume Status ◽  
Non Invasive ◽  
Collapsibility Index ◽  
Fractional Excretion Of Sodium ◽  
Status Assessment

Abstract Evaluating the volume status in children with Idiopathic nephrotic syndrome (INS) is mandatory to guide treatment and avoid unnecessary possibly hazardous albumin use. This study aimed to evaluate and compare the available tools used for volume status assessment and differentiating type of edema in children with INS. Sixty children with active INS were included and subdivided into hypovolemic and non-hypovolemic groups based on fractional excretion of sodium (FeNa%) and clinical assessment. All patients were studied for Inferior vena cava collapsibility index (IVCCI), plasma atrial natriuretic peptide (ANP) concentration and Body composition monitor (BCM). Forty-four patients (77.3%) had non-hypovolemic and 16 (26.7%) had hypovolemic states. Plasma ANP levels didn’t differ between hypovolemic and non-hypovolemic subgroups. IVCCI was higher in hypovolemic group (p<0.001) with sensitivity 87.5% and specificity 81.8% for hypovolemia detection while BCM-over hydration (BCM-OH) values were higher in non-hypovolemic group (p=0.04) with sensitivity= 68.2% and specificity =75% for detection of hypervolemia. FeNa% showed negative significant correlation with IVCCI (r= -0.578, p <0.001) and positive significant correlation with BCM-OH (r= 0.33, p=0.018), while FeNa% showed non-significant correlation to plasma ANP concentration (p=0.25). Conclusion: Non-hypovolemic edema is more frequent in edematous INS children than hypovolemic states. IVCCI is a reliable non-invasive bedside tool for evaluating volume status in INS children and is superior to BCM while plasma ANP levels can’t discriminate type of edema in INS.

scholarly journals A young woman presented with massive pulmonary embolism with inferior vena cava thrombus as a complication of nephrotic syndrome: a case report

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Mohamed Osman Omar Jeele ◽  
Rukia Omar Barei Addow ◽  
Mohamed Farah Yusuf Mohamud
Keyword(s):  
Pulmonary Embolism ◽  
Nephrotic Syndrome ◽  
Inferior Vena Cava ◽  
Inferior Vena ◽  
Vena Cava ◽  
Oral Prednisolone ◽  
Massive Pulmonary Embolism ◽  
Thrombotic Risk ◽  
Vena Cava Thrombosis ◽  
Inferior Vena Cava Thrombosis

AbstractNephrotic syndrome (NS) was first described in 1827 as the presence of proteinuria of ≥ 3.5 g/24 h, hypoalbuminemia < 3.0 g/dl, peripheral edema, hyperlipidemia, lipiduria, and increased thrombotic risk. Nephrotic syndrome has an incidence of three cases per 100,000 each year in adults. Nephrotic syndrome also has serious complications due to hypercoagulable state in both various venous and arteries which could lead thromboembolic events. The pathophysiology of hypercoagulability in the nephrotic syndrome is due to an imbalance of prothrombotic and antithrombotic factors, as well as impaired thrombolytic activities.Here, we will present a 19-year-old woman who presented to the emergency department complaining of chest pain and shortness of breath for 3 days. The patient was quickly diagnosed with pulmonary embolism and inferior vena cava thrombosis as a complication of nephrotic syndrome, allowing prompt initiation of anticoagulant therapy. After 2 weeks of admission, the patient’s condition resolved, her laboratory results returned to almost normal and the patient was discharged with oral prednisolone, coumadin, atorvastatin, and ramipril. We aim to determine which is the likely cause of pulmonary embolism in patients with nephrotic syndrome.

A Young Female Presented With Massive Pulmonary Embolism Wıth Inferior Vena Cava Thrombus as a Complication of Nephrotic Syndrome: A Case Report

2020 ◽  
Author(s):  
Mohamed Osman Jeele ◽  
Mohamed Farah Yusuf Mohamud ◽  
Rukia Omar Barre Addow
Keyword(s):  
Pulmonary Embolism ◽  
Nephrotic Syndrome ◽  
Inferior Vena Cava ◽  
Inferior Vena ◽  
Vena Cava ◽  
Oral Prednisolone ◽  
Massive Pulmonary Embolism ◽  
Young Female ◽  
Thrombolytic Activity ◽  
Thrombotic Risk

Abstract Nephrotic syndrome (NS); the first described in 1827 as the presence of proteinuria of ≥ 3.5 g/24 hours, albuminemia < 3.0 g, peripheral edema, hyperlipidemia, lipiduria, and increased thrombotic risk which has an incidence of three new cases per 100 000 each year in adults. Nephrotic syndrome had complicated by the induction of a hypercoagulable state with both various venous and arterial thromboembolic events. The pathophysiology of hypercoagulability in the nephrotic syndrome is imbalances of prothrombotic and antithrombotic factors, as well as impaired thrombolytic activity occurs. Here we present, a 19 years old female came to the emergency department with a complaint of chest pain and shortness of breath for three days. The patient quickly diagnosed pulmonary embolism and inferior vena cava thrombosis as a complication of nephrotic syndrome, allowing prompt initiation of anticoagulant therapy. After two weeks of admission, the patient's resolved dramatically, and his laboratory results returned to almost normal, and the patient discharged with Oral Prednisolone, Coumadin, Atorvastatin, and Ramipril. We aim to determine which is the likely cause of pulmonary embolism in patients with the nephrotic syndrome.

The “Fisherman’s Waders” sign in a bone scan of inferior vena cava thrombosis associated with nephrotic syndrome

1995 ◽  
Vol 9 (4) ◽  
pp. 237-241 ◽  
Author(s):  
Lee-shing Chu ◽  
Cheng-pei Chang ◽  
Ren-shyan Liu ◽  
Sinclair Wynchank ◽  
Ming-huei Sheu ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Inferior Vena Cava ◽  
Bone Scan ◽  
Inferior Vena ◽  
Vena Cava ◽  
Vena Cava Thrombosis ◽  
Inferior Vena Cava Thrombosis

scholarly journals Comparison of the inferior vena cava index and inferior vena cava collapsibility index obtained by ultrasound as a measure of body fluid volume status in children with nephrotic syndrome

2019 ◽  
Vol 6 (3) ◽  
pp. 1298
Author(s):  
Deepesh Gupta ◽  
Kusum Devpura ◽  
Kamlesh Kumar Agrawal
Keyword(s):  
Nephrotic Syndrome ◽  
Inferior Vena Cava ◽  
Body Fluid ◽  
Inferior Vena ◽  
Vena Cava ◽  
Mean Value ◽  
Fluid Volume ◽  
Volume Status ◽  
Minimum Diameter ◽  
Body Fluid Volume

Background: There is triad of hypoalbuminemia, edema, and hyperlipidemia in nephrotic syndrome patients. Management of nephrotic syndrome includes general measures like fluid restriction, emergency albumin transfusions and diuretics that provide symptomatic relief till steroids act. These measures require an assessment of body fluid volume to avoid circulatory failure which is very difficult in these patients because of edema. The objective of the study was to measure and compare the Inferior Vena Cava (IVC) Index and Inferior Vena Cava Collapsibility (IVCC) Index by ultrasound as a measure of body fluid volume status in children with nephrotic syndrome.Methods: The present observational study was conducted in all children of age more than 1 year up to 18 year. There were two groups; group 1 was nephrotic syndrome patients-Initial episode or in relapse and group 2 (Control) was age and sex-matched non-nephrotic children. IVC index and IVCC index were measured and compared in both the groups.Results: Mean value of minimum diameter of IVC during inspiration in cases was 5.91±1.60 mm as compared to 4.53±0.94 mm in controls which was significantly higher in case group {P ˂0.0001}. Mean value of IVC index in cases was 0.88±0.20 cm/m2 as compared to 0.93±0.19 cm/m2 in controls which was non-significant. Mean value of IVCC index in cases (35.61±13.68) was significantly less as compared to controls (52.23±2.01) {P ˂0.0001}.Conclusions: The present study concluded that IVCC index is better indicator of body fluid volume status in nephrotic patients as compare to IVC index.

Effective vascular compliance and venous diameter in dogs

1976 ◽  
Vol 54 (2) ◽  
pp. 154-159 ◽  
Author(s):  
Pierre Larochelle ◽  
Richard I. Ogilvie
Keyword(s):  
Inferior Vena Cava ◽  
Inferior Vena ◽  
Vena Cava ◽  
Wall Tension ◽  
Aortic Constriction ◽  
Vascular Compliance ◽  
Volume Load ◽  
Venous Diameter ◽  
Venous Wall ◽  
Effective Vascular Compliance

Total effective vascular compliance was measured repeatedly in open-chest dogs without circulatory arrest, utilizing a closed-circuit venous bypass system with a constant cardiac output. Mutual inductance coils were used to measure the diameter of the inferior vena cava above the diaphragm at the position where the pressure change was recorded during a volume load (ΔV). In all experiments, there was a relationship which tended to be curvilinear between the diameter of the inferior vena cava and the venous pressure before ΔV. No relationship was demonstrated between the initial diameter or pressure and the calculated effective vascular compliance. During aortic constriction or infusion of noradrenaline, the effective compliance was reduced in value at any given initial venous diameter and pressure. An unaltered venous diameter and plasma volume excluded the possibility of a large change in initial venous volume as a cause of the observed changes in compliance during aortic constriction or during infusion of noradrenaline. A relationship was observed between compliance and calculated venous wall tension so that as the wall tension, developed during a fixed volume load, increased, there was an associated reduction in compliance. These results demonstrate that the measurement of effective compliance provides an assessment of combined active and passive venous wall tension and venous tone.

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