An ultrastructure study of the in vitro effects of L -leucine methyl ester and ammonium chloride on Trypanosoma cruzi epimastigotes

1996 ◽  
Vol 82 (4) ◽  
pp. 285-290 ◽  
Author(s):  
B. J. Bogitsh ◽  
R. Ribeiro-Rodrigues ◽  
C. E. Carter
Keyword(s):  
Methyl Ester ◽  
Trypanosoma Cruzi ◽  
Ammonium Chloride ◽  
Ultrastructure Study ◽  
In Vitro Effects

Trypanocidal Activity of Oleoresin and Terpenoids Isolated from Pinus oocarpa

2005 ◽  
Vol 60 (9-10) ◽  
pp. 711-716 ◽  
Author(s):  
Julieta Rubio ◽  
José S. Calderón ◽  
Angélica Flores ◽  
Clementina Castro ◽  
Carlos L. Céspedes
Keyword(s):  
Methyl Ester ◽  
Trypanosoma Cruzi ◽  
Acute Infection ◽  
Acid Methyl Ester ◽  
Positive Control ◽  
Dehydroabietic Acid ◽  
Isopimaric Acid ◽  
Acid Methyl ◽  
Pinus Oocarpa

Abstract Fractionation with n-hexane/ethyl acetate (1:1 v/v) by open column chromatography of the oleoresin from Pinus oocarpa Schiede yielded two diterpenes, pimaric acid (1) and dehydroabietic acid (5), the sesquiterpene longifolene (3) and a diterpenic mixture containing pimaric acid (1), isopimaric acid (4) and dehydroabietic acid (5). Subsequently, the isolated compounds, the mixture of 1, 4 and 5, the oleoresin and the dehydroabietic acid methyl ester (2), were tested in vitro against epimastigotes of Trypanosoma cruzi, the causative agent of Chagas disease. The most active compounds were 1, 3 and the oleoresin, being as active as nifurtimox, a drug effective in the treatment of acute infection by American trypanosomiasis and used in this work as positive control.

In vitro effects of suramin on Trypanosoma cruzi

2008 ◽  
Vol 31 (3) ◽  
pp. 282-286 ◽  
Author(s):  
Danielle Frias Ribeiro Bisaggio ◽  
Camila Marques Adade ◽  
Thaïs Souto-Padrón
Keyword(s):  
Trypanosoma Cruzi ◽  
In Vitro Effects

scholarly journals In vitro effects of citral on Trypanosoma cruzi metacyclogenesis

2010 ◽  
Vol 105 (8) ◽  
pp. 1026-1032 ◽  
Author(s):  
Josiane Cardoso ◽  
Maurilio José Soares
Keyword(s):  
Trypanosoma Cruzi ◽  
In Vitro Effects

In Vivo and in Vitro Effects of Cyclosporin A on Trypanosoma Cruzi *

1985 ◽  
Vol 34 (5) ◽  
pp. 861-865 ◽  
Author(s):  
R. E. McCabe ◽  
J. S. Remington ◽  
F. G. Araujo
Keyword(s):  
Trypanosoma Cruzi ◽  
Cyclosporin A ◽  
In Vitro Effects

Selective in vitro effects of the farnesyl pyrophosphate synthase inhibitor risedronate on Trypanosoma cruzi

2004 ◽  
Vol 23 (3) ◽  
pp. 273-285 ◽  
Author(s):  
Luciana R. Garzoni ◽  
Aura Caldera ◽  
Maria de Nazareth L. Meirelles ◽  
Solange L.de Castro ◽  
Roberto Docampo ◽  
...  
Keyword(s):  
Trypanosoma Cruzi ◽  
Farnesyl Pyrophosphate ◽  
Farnesyl Pyrophosphate Synthase ◽  
In Vitro Effects ◽  
Synthase Inhibitor

In vitro effects of prodigiosin and other antibiotics on Trypanosoma cruzi

1953 ◽  
Vol 2 (2) ◽  
pp. 125-128 ◽  
Author(s):  
W.L McRary ◽  
E.L. Beaver ◽  
E.R. Noble
Keyword(s):  
Trypanosoma Cruzi ◽  
In Vitro Effects
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