Solitary fibrous tumour: clinicopathological, immunohistochemical, and ultrastructural analysis of 12 cases arising in soft tissues, nasal cavity and nasopharynx, urinary bladder and prostate

1997 ◽  
Vol 430 (6) ◽  
pp. 445-453 ◽  
Author(s):  
T. Mentzel ◽  
T. C. Bainbridge ◽  
D. Katenkamp
Keyword(s):  
Urinary Bladder ◽  
Nasal Cavity ◽  
Soft Tissues ◽  
Solitary Fibrous Tumour ◽  
Ultrastructural Analysis

Histologic, Histochemical, and Ultrastructural Analysis of Soft Tissues from Cleft and Normal Lips

2001 ◽  
Vol 108 (3) ◽  
pp. 605-611 ◽  
Author(s):  
Tristan de Chalain ◽  
Ronald Zuker ◽  
Cameron Ackerley
Keyword(s):  
Soft Tissues ◽  
Ultrastructural Analysis

scholarly journals Malignant peripheral nerve sheath tumour in an unusual location of the urinary bladder: case report and review of literature

2021 ◽  
Vol 27 (1) ◽  
Author(s):  
Mustapha A. Ajani ◽  
Babatope L. Awosusi ◽  
Ifeanyichukwu D. Nwanji
Keyword(s):  
Urinary Bladder ◽  
Peripheral Nerve ◽  
Soft Tissues ◽  
Digital Rectal Examination ◽  
Immunohistochemical Analysis ◽  
Posterior Wall ◽  
Tumour Mass ◽  
Nerve Sheath Tumour ◽  
Nerve Sheath ◽  
Peripheral Nerve Sheath Tumour

Abstract Background Malignant peripheral nerve sheath tumour (MPNST) is a rare malignant soft tissue neoplasm of ectomesenchymal origin. They usually arise from a major or minor peripheral nerve branch or its sheath and also from somatic soft tissues. The most common sites of origin include the extremities and trunk but can sometimes arise an unusual site resulting in the demise of the patient before any intervention. Case presentation We report a case of 58-year-old male who presented with complaints of weight loss of a year duration, abdominal swelling of 10 months duration and easy fatigability of 3 weeks duration. Digital rectal examination revealed a huge firm mass 6 cm from the anal verge which was non-tender. Abdomino-pelvic ultrasound scan revealed an irregular heterogeneous mass in the posterior wall of the urinary bladder measuring 15.1cmx 14.0 cm with bilateral dilatation of the renal pelvi-calyceal system and ureters. His clinical condition continued to deteriorate while on hospital admission, and he died on the12th day of admission. Post-mortem examination showed a rough ovoid tumour mass firmly adherent to the posterior wall of the bladder with compression of both ureters. Histological and immunohistochemical analysis of the tumour revealed the diagnosis of a MPNST. The final anatomical diagnosis and cause of death was that of a malignant peripheral nerve sheath tumour of the urinary bladder with obstructive uropathy and severe sepsis. Conclusion MPNST can arise at unusual sites other than its common location in the extremities and the existence of neurofibromatosis may not be present. High index of suspicion of MPNST should be raised in rapidly growing painless tumour in and around a nerve tissue. Prompt radio-imaging with biopsy and expert immunohistochemical analysis of lesions will lead to early diagnosis and intervention. Molecular targeted therapies following surgery for MPNST should be developed to improve prognosis and patient outcomes.

scholarly journals What Does Nasal Cavity Size Tell us about Functional Nasal Airways?

2018 ◽  
Vol 31 (1-2) ◽  
pp. 69-76 ◽  
Author(s):  
Y. Heuzé
Keyword(s):  
Nasal Cavity ◽  
Air Conditioning ◽  
Soft Tissues ◽  
Volume Ratio ◽  
University Hospital ◽  
Facial Morphology ◽  
Nasal Airways ◽  
Computed Tomography Images ◽  
Low Correlation ◽  
Human Skulls

Studies on dry human skulls have shown that nasal cavity (NC) morphology varies with eco-geographic factors. These findings have been used by some authors to interpret the facial morphology of Neanderthals. However, respiratory and air-conditioning functions are primarily carried out by the nasal airways (NA), which are delimited by mucosa. The aims of this study were to test whether: (1) NC volume (V) and surface-area-to-volume ratio (SA/ V) are proportional to NA counterparts; (2) measurements for male NC and NA are larger than in females; (3) the centroid size (CS) of a set of landmarks measured on NC provides a reliable proxy for NC V. Head CT (computed tomography) images of adult patients (N = 30) at the University Hospital of Bordeaux were selected retrospectively. NA were defined by segmenting the lumen corresponding to the functional volume. NC was defined by adding to NA the soft tissues delimited by the bones forming the NC. The coordinates of 16 landmarks measured on NC bones were recorded. A rather low correlation was found between NA and NC V while NA SA/V and NC SA/V were not correlated. No significant differences were found between male and female NA and NC measurements. A rather low correlation was found between NC Vand NC CS. If these preliminary results were to be confirmed by future studies, results using NC as a proxy for NA focusing on air-conditioning and respiratory energetics might need to be re-interpreted.

scholarly journals Clinical analysis of CT and MRI Features of Solitary Fibrous Tumour of the Soft Tissues

2017 ◽  
Vol 07 (06) ◽  
Author(s):  
Qian Yin Feng ◽  
Surya Narayan Bayar ◽  
Mohammad Abdul Mazid ◽  
Deepak Bhandari ◽  
Li Xiao Hu ◽  
...  
Keyword(s):  
Soft Tissues ◽  
Clinical Analysis ◽  
Solitary Fibrous Tumour ◽  
Mri Features ◽  
Ct And Mri

Angioleiomyosarcoma in the Nasal Vestibule of a Dog: Surgical Excision via a Modified Lateral Approach

2015 ◽  
Vol 51 (2) ◽  
pp. 130-135 ◽  
Author(s):  
Jayne A. McGhie ◽  
Louise FitzGerald ◽  
Giselle Hosgood
Keyword(s):  
Nasal Cavity ◽  
Soft Tissues ◽  
Soft Tissue Sarcomas ◽  
Surgical Excision ◽  
Lateral Approach ◽  
Left Nasal Cavity ◽  
German Shepherd ◽  
Nasal Vestibule ◽  
German Shepherd Dog ◽  
Wall Tumor

This case report describes an 11 yr old spayed female German shepherd dog weighing 42 kg that presented with intermittent epistaxis from the left nostril. A nonulcerated pale irregular polypoid mass was visualized within the left nares. Computed tomography revealed a pedunculated mass arising from the ventrolateral nasal mucosal of the left nasal cavity with no evidence of involvement or invasion of adjacent soft tissues or bony structures. Histological and immunohistochemical examination of rhinoscopic biopsies returned a diagnosis of an angioleiomyosarcoma. The mass was excised using a modified lateral approach to the nasal cavity. Fulguration of the wound bed was performed. Clean surgical margins were identified on histopathology. The dog remained clinically free of recurrence 28 mo postsurgically. Angioleiomyosarcomas are rare tumors originating from the smooth muscle cells of blood vessel walls and are included in the spectrum of perivascular wall tumor, a subgroup of soft-tissue sarcomas.

Tumours in European Shorthair cats: a retrospective study of 680 cases

2020 ◽  
Vol 22 (12) ◽  
pp. 1095-1102 ◽  
Author(s):  
Elisabetta Manuali ◽  
Claudio Forte ◽  
Gaia Vichi ◽  
Domenica Anna Genovese ◽  
Danilo Mancini ◽  
...  
Keyword(s):  
Mammary Gland ◽  
Nasal Cavity ◽  
Middle Ear ◽  
Soft Tissues ◽  
Prolonged Exposure ◽  
Central Italy ◽  
Intrahepatic Bile Duct ◽  
World Health ◽  
Malignant Tumours ◽  
Data Set

Objectives Naturally occurring tumours in domestic cats are less common than in dogs and represent the leading cause of death among older animals. The main objective of this study was to analyse a large data set of histologically diagnosed tumours to highlight the most common World Health Organization (WHO) tumour histotypes, the effect of age and sex, and the International Classification of Diseases for Oncology (ICD-O) topographical site predilections of feline breed-specific tumours. Methods A total of 680 feline tumours diagnosed in European Shorthair cats by three veterinary diagnostic laboratories located in central Italy from 2013 to 2019 were collected. Data on age, sex and topography of lesions were recorded. Samples were morphologically and topographically coded using the WHO and the ICD-O-3 classification system. Results Skin and soft tissue neoplasms comprised 55.9% of all tumours, followed by mammary gland (11%), alimentary tract (7.9%), oral cavity and tongue (7.3%), nasal cavity and middle ear (6%), lymph node (3.1%), bone (1.8%) and liver/intrahepatic bile duct (1.3%) tumours. Squamous cell carcinoma (SCC), sarcoma, lymphoma and basal cell tumours were the most diagnosed neoplasms. Malignant tumours were 82.9% of the total and the topographical sites mainly involved were skin (C44), connective/subcutaneous/other soft tissues (C49), mammary gland (C50), small intestine (C17), nasal cavity and middle ear (C30), and gum (C03). Conclusions and relevance This study aimed to provide an in-depth evaluation of spontaneous feline tumours in the European Shorthair cat breed. Results identify SCC as the most commonly represented skin neoplasm. It is likely that the analysed feline population, living in southern latitudes, was more subject to prolonged exposure to ultraviolet light, explaining the discrepancy with previous studies in which SCC was less represented.

The Covenant of NOA: Neighbouring Organ Assistance (NOA) to Soft Tissue Structures

2003 ◽  
Author(s):  
C. P. Arun
Keyword(s):  
Soft Tissue ◽  
Urinary Bladder ◽  
Soft Tissues ◽  
Calf Muscle ◽  
Intensive Study ◽  
Hollow Structures ◽  
Calf Muscle Pump ◽  
General Law ◽  
Pelvic Diaphragm ◽  
Tissue Structures

Soft tissues hollow structures are capable of collapsing not only under their own power but also able to employ movements of their neighbors to aid their function of propelling content. An intensive study of collapsible hollow structures is a recent development and no general law recognising this convenient coupling of the dynamics of neighboring organs is available in the literature. The literature on whole organ physiology was analysed and examples of neighboring organs providing assistance to soft tissue structures was collected. We offer the title Covenant of NOA to the arrangement that soft tissue structures have with their neighbors. The calf muscle pump and parturition are obvious examples of NOA. From examining videocystometric recordings, we are able to offer, as the latest to a long list of known NOAs, the assistance of the pelvic diaphragm to the urinary bladder that aids the latter in emptying completely. The modeling of soft tissue hollow organs as functioning somewhat in isolation must be considered antediluvian. Very often, soft tissue structures come in pairs to implement NOA: it is time we too hearkened to the Covenant of NOA.

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