The carp homeobox gene Ovx1 shows early expression during gastrulation and subsequently in the vagal lobe, the facial lobe and the ventral telencephalon

H. W. J. Stroband; Marcus P. S. Dekens; Geertruy te Kronnie; Henk Schipper; Johannis Samallo

doi:10.1007/s004270050154

The carp homeobox gene Ovx1 shows early expression during gastrulation and subsequently in the vagal lobe, the facial lobe and the ventral telencephalon

Development Genes and Evolution ◽

10.1007/s004270050154 ◽

1998 ◽

Vol 208 (1) ◽

pp. 56-59 ◽

Cited By ~ 3

Author(s):

H. W. J. Stroband ◽

Marcus P. S. Dekens ◽

Geertruy te Kronnie ◽

Henk Schipper ◽

Johannis Samallo

Keyword(s):

Homeobox Gene ◽

Ventral Telencephalon ◽

Early Expression ◽

Vagal Lobe

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Induction of a mesencephalic phenotype in the 2-day-old chick prosencephalon is preceded by the early expression of the homeobox gene en

Neuron ◽

10.1016/0896-6273(91)90237-t ◽

1991 ◽

Vol 6 (6) ◽

pp. 971-981 ◽

Cited By ~ 210

Author(s):

Salvador Martinez ◽

Marion Wassef ◽

Rosa-Magda Alvarado-Mallart

Keyword(s):

Homeobox Gene ◽

Early Expression

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A conserved retinoic acid response element required for early expression of the homeobox gene Hoxb-1

Nature ◽

10.1038/370567a0 ◽

1994 ◽

Vol 370 (6490) ◽

pp. 567-571 ◽

Cited By ~ 276

Author(s):

Heather Marshall ◽

Michèle Studer ◽

Heike Pöpperl ◽

Sam Aparicio ◽

Atsushi Kuroiwa ◽

...

Keyword(s):

Retinoic Acid ◽

Homeobox Gene ◽

Response Element ◽

Retinoic Acid Response Element ◽

Early Expression

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Rpx: a novel anterior-restricted homeobox gene progressively activated in the prechordal plate, anterior neural plate and Rathke's pouch of the mouse embryo

Development ◽

10.1242/dev.122.1.41 ◽

1996 ◽

Vol 122 (1) ◽

pp. 41-52 ◽

Cited By ~ 23

Author(s):

E. Hermesz ◽

S. Mackem ◽

K.A. Mahon

Keyword(s):

Homeobox Gene ◽

Cell Types ◽

Early Embryo ◽

Neural Plate ◽

Specific Cell ◽

Expression Domain ◽

Rathke’S Pouch ◽

Rathke's Pouch ◽

Prechordal Plate ◽

Early Expression

We have isolated a new murine homeobox gene, Rpx (for Rathke's pouch homeobox), that is dynamically expressed in the prospective cephalic region of the embryo during gastrulation. Early expression is seen in the anterior midline endoderm and prechordal plate precursor. Expression is subsequently activated in the overlying ectoderm of the cephalic neural plate, suggesting that inductive contact with Rpx-expressing mesendoderm is required for this expression. Subsequently, Rpx expression is extinguished in the mesendoderm while remaining in the prospective prosencephalic region of the neural plate ectoderm. Ultimately, transcripts become restricted to Rathke's pouch, the primordium of the pituitary, which is known to be derived from the most anterior ectoderm of the early embryo. Down regulation of Rpx in the pouch coincides with the differentiation of pituitary-specific cell types. Rpx is the earliest known marker for the pituitary primordium, suggestive of a role in the early determination or differentiation of the pituitary. Since Rpx is expressed so dynamically and so early in the anterior region of the embryo, and since its early expression domain is much more extensive than the region fated to form the pituitary, it is likely that Rpx is involved in the initial determination of the anterior (prechordal) region of the embryo.

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