Effect of short-term creatine supplementation on renal responses in men

1997 ◽  
Vol 76 (6) ◽  
pp. 566-567 ◽  
Author(s):  
J. R. Poortmans ◽  
H. Auquier ◽  
V. Renaut ◽  
A. Durussel ◽  
M. Saugy ◽  
...  
2017 ◽  
Vol 10 (1) ◽  
pp. 31-34 ◽  
Author(s):  
Jessica Butts ◽  
Bret Jacobs ◽  
Matthew Silvis

Context: The use of creatine as a dietary supplement has become increasingly popular over the past several decades. Despite the popularity of creatine, questions remain with regard to dosing, effects on sports performance, and safety. Evidence Acquisition: PubMed was searched for articles published between 1980 and January 2017 using the terms creatine, creatine supplementation, sports performance, and dietary supplements. An additional Google search was performed to capture National Collegiate Athletic Association–specific creatine usage data and US dietary supplement and creatine sales. Study Design: Clinical review. Level of Evidence: Level 4. Results: Short-term use of creatine is considered safe and without significant adverse effects, although caution should be advised as the number of long-term studies is limited. Suggested dosing is variable, with many different regimens showing benefits. The safety of creatine supplementation has not been studied in children and adolescents. Currently, the scientific literature best supports creatine supplementation for increased performance in short-duration, maximal-intensity resistance training. Conclusion: While creatine appears to be safe and effective for particular settings, whether creatine supplementation leads to improved performance on the field of play remains unknown.


2002 ◽  
Vol 92 (2) ◽  
pp. 513-518 ◽  
Author(s):  
P. Hespel ◽  
B. Op ‘t Eijnde ◽  
M. Van Leemputte

The effect of creatine and caffeine supplementation on muscle torque generation and relaxation was investigated in healthy male volunteers. Maximal torque (Tmax), contraction time (CT) from 0.25 to 0.75 of Tmax, and relaxation time (RT) from 0.75 to 0.25 of Tmax were measured during an exercise test consisting of 30 intermittent contractions of musculus quadriceps (2 s stimulation, 2 s rest) that were induced by electrical stimulation. According to a double-blind randomized crossover design, subjects ( n = 10) performed the exercise test before (pretest) and after (posttest) creatine supplementation (Cr, 4 × 5 g/day, 4 days), short-term caffeine intake (Caf, 5 mg · kg−1 · day−1, 3 days), creatine supplementation + short-term caffeine intake (Cr+Caf), acute caffeine intake (ACaf, 5 mg/kg) or placebo. Compared with placebo, Cr shortened RT by ∼5% ( P < 0.05). Conversely, Caf increased RT (+∼10%, P < 0.05), in particular as RT increased because of fatigue. RT was not significantly changed by either Cr+Caf or ACaf. Tmax and CT were similar during all experimental conditions. Initial Tmax was ∼20% of voluntary maximal isometric contraction force, which was not different between treatments. It is concluded that Caf intake (3 days) prolongs muscle RT and by this action overrides the shortening of RT due to creatine supplementation.


2004 ◽  
Vol 91 (5-6) ◽  
pp. 628-637 ◽  
Author(s):  
Jeff S. Volek ◽  
Nicholas A. Ratamess ◽  
Martyn R. Rubin ◽  
Ana L. G�mez ◽  
Duncan N. French ◽  
...  

1998 ◽  
Vol 30 (Supplement) ◽  
pp. 265
Author(s):  
W. Y. Ensign ◽  
I. Jacobs ◽  
W. K. Prusaczyk ◽  
H. W. Goforth ◽  
P. G. Law ◽  
...  

2009 ◽  
Vol 108 (5) ◽  
pp. 945-955 ◽  
Author(s):  
Reinaldo Abunasser Bassit ◽  
Carlos Hermano da Justa Pinheiro ◽  
Kaio Fernando Vitzel ◽  
Antônio José Sproesser ◽  
Leonardo R. Silveira ◽  
...  

Author(s):  
Wayne Y. Ensign ◽  
Ira Jacobs ◽  
William K. Prusaczyk ◽  
Harold W. Goforth ◽  
Patty G. Law ◽  
...  

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