Site-selective immobilization of gold nanoparticles functionalized with DNA oligomers

2001 ◽  
Vol 279 (1) ◽  
pp. 68-72 ◽  
Author(s):  
C. M. Niemeyer ◽  
B. Ceyhan ◽  
S. Gao ◽  
L. Chi ◽  
S. Peschel ◽  
...  
2014 ◽  
Vol 315 ◽  
pp. 73-80 ◽  
Author(s):  
Jea Uk Lee ◽  
Wonoh Lee ◽  
Sang Su Yoon ◽  
Jungwook Kim ◽  
Joon Hyung Byun

Langmuir ◽  
2012 ◽  
Vol 28 (20) ◽  
pp. 7579-7584 ◽  
Author(s):  
Jeonghyeon Yang ◽  
Takashi Ichii ◽  
Kuniaki Murase ◽  
Hiroyuki Sugimura

2010 ◽  
Vol 46 (22) ◽  
pp. 3863 ◽  
Author(s):  
Hyun Joo Jung ◽  
Hyegeun Min ◽  
Hyunung Yu ◽  
Tae Geol Lee ◽  
Taek Dong Chung

2005 ◽  
Vol 56 (7) ◽  
pp. 427-428
Author(s):  
Kensuke AKAMATSU ◽  
Hiroaki TERAHATA ◽  
Jun HASEGAWA ◽  
Hidemi NAWAFUNE

2015 ◽  
Vol 16 (4) ◽  
Author(s):  
Svea Petersen ◽  
Christiane Häcker ◽  
Gökmen Turan ◽  
Stefanie Knödler ◽  
Andreas Brodehl ◽  
...  

AbstractFunctionality of implant surfaces is considerably determined by the conformations of immobilized biomolecules adjustable by the applied surface modification approach. Moreover, surface modification of drug eluting systems often needs to be thoroughly optimized with regard to possible drug losses associated with a loss of functionality. Here, we thoroughly investigate biomolecule surface loading, functionality, morphology and stability in dependence of modification conditions at the example of a site-selective immobilization of anti-CD34 antibodies (CD34-Ab) to drug-eluting stents with the aim of providing general information on the biofunctionalization of drug eluting systems. In this context, we demonstrate that the reaction time of biomolecule immobilization defines achievable surface loads but also drug loss. We could moreover show that the used site-selective immobilization procedure elevated the surface functionality considerably in comparison to surfaces modified by random physisorption. Furthermore investigated bionfunctional stability gives important indications for storage conditions of biofunctionalized implants.


2007 ◽  
Vol 138 (4) ◽  
pp. 309-314 ◽  
Author(s):  
Martin R. Weinberger ◽  
Stephan Rentenberger ◽  
Wolfgang Kern

1998 ◽  
Vol 10 (6) ◽  
pp. 1510-1520 ◽  
Author(s):  
Melanie S. Sanford ◽  
Paul T. Charles ◽  
Sarah M. Commisso ◽  
Jenna C. Roberts ◽  
David W. Conrad

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