Site-Selective Immobilization of Ligands with Control of Density on Electroactive Microelectrode Arrays

ChemPhysChem ◽  
2007 ◽  
Vol 8 (10) ◽  
pp. 1469-1472 ◽  
Author(s):  
Eugene W. L. Chan ◽  
Muhammad N. Yousaf
Keyword(s):  
Microelectrode Arrays ◽  
Selective Immobilization ◽  
Site Selective

scholarly journals Building Addressable Libraries: Site-Selective Suzuki Reactions on Microelectrode Arrays

2009 ◽  
Vol 11 (6) ◽  
pp. 1273-1276 ◽  
Author(s):  
Libo Hu ◽  
Karl Maurer ◽  
Kevin D. Moeller
Keyword(s):  
Microelectrode Arrays ◽  
Suzuki Reactions ◽  
Site Selective

Electrochemical cleavage of azo linkage for site-selective immobilization and cell patterning

2010 ◽  
Vol 46 (22) ◽  
pp. 3863 ◽  
Author(s):  
Hyun Joo Jung ◽  
Hyegeun Min ◽  
Hyunung Yu ◽  
Tae Geol Lee ◽  
Taek Dong Chung
Keyword(s):  
Cell Patterning ◽  
Selective Immobilization ◽  
Site Selective

Implications for the biofunctionalization of drug-eluting devices at the example of a site-selective antibody modification for drug eluting stents

2015 ◽  
Vol 16 (4) ◽  
Author(s):  
Svea Petersen ◽  
Christiane Häcker ◽  
Gökmen Turan ◽  
Stefanie Knödler ◽  
Andreas Brodehl ◽  
...  
Keyword(s):  
Surface Modification ◽  
Storage Conditions ◽  
General Information ◽  
Drug Eluting Stents ◽  
Surface Loading ◽  
Surface Functionality ◽  
Drug Eluting ◽  
A Site ◽  
Selective Immobilization ◽  
Site Selective

AbstractFunctionality of implant surfaces is considerably determined by the conformations of immobilized biomolecules adjustable by the applied surface modification approach. Moreover, surface modification of drug eluting systems often needs to be thoroughly optimized with regard to possible drug losses associated with a loss of functionality. Here, we thoroughly investigate biomolecule surface loading, functionality, morphology and stability in dependence of modification conditions at the example of a site-selective immobilization of anti-CD34 antibodies (CD34-Ab) to drug-eluting stents with the aim of providing general information on the biofunctionalization of drug eluting systems. In this context, we demonstrate that the reaction time of biomolecule immobilization defines achievable surface loads but also drug loss. We could moreover show that the used site-selective immobilization procedure elevated the surface functionality considerably in comparison to surfaces modified by random physisorption. Furthermore investigated bionfunctional stability gives important indications for storage conditions of biofunctionalized implants.

Photoactivatable Cross-Linked Polyacrylamide for the Site-Selective Immobilization of Antigens and Antibodies

1998 ◽  
Vol 10 (6) ◽  
pp. 1510-1520 ◽  
Author(s):  
Melanie S. Sanford ◽  
Paul T. Charles ◽  
Sarah M. Commisso ◽  
Jenna C. Roberts ◽  
David W. Conrad
Keyword(s):  
Selective Immobilization ◽  
Site Selective

scholarly journals Building Addressable Libraries: Site-Selective Use of Pd(0) Catalysts on Microelectrode Arrays

2010 ◽  
Vol 132 (46) ◽  
pp. 16610-16616 ◽  
Author(s):  
Libo Hu ◽  
Melissae Stuart ◽  
Jun Tian ◽  
Karl Maurer ◽  
Kevin D. Moeller
Keyword(s):  
Microelectrode Arrays ◽  
Site Selective

Site-selective immobilization of gold nanoparticles functionalized with DNA oligomers

2001 ◽  
Vol 279 (1) ◽  
pp. 68-72 ◽  
Author(s):  
C. M. Niemeyer ◽  
B. Ceyhan ◽  
S. Gao ◽  
L. Chi ◽  
S. Peschel ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Dna Oligomers ◽  
Selective Immobilization ◽  
Site Selective

scholarly journals Site-selective immobilization of functionalized DNA origami on nanopatterned Teflon AF

2017 ◽  
Vol 5 (30) ◽  
pp. 7637-7643 ◽  
Author(s):  
M. Shaali ◽  
J. G. Woller ◽  
P. G. Johansson ◽  
J. K. Hannestad ◽  
L. de Battice ◽  
...  
Keyword(s):  
Precise Determination ◽  
Dna Origami ◽  
Dna Molecules ◽  
Single Dna Molecules ◽  
Teflon Af ◽  
Selective Immobilization ◽  
Site Selective

Teflon AF acts as a negative e-beam resist, here utilized for immobilization of porphyrin-anchored single DNA molecules on nanopillars, and precise determination of individual label positions.

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