Comparison of the efficacy of ER-YAG laser sclerostomy ab externo versus trabeculectomy in the treatment of patients with primary open – angle glaucoma

1998 ◽  
Vol 95 (8) ◽  
pp. 537-541 ◽  
Author(s):  
Detlev Spiegel ◽  
Wolfgang Wetzel ◽  
Reginald Birngruber
Keyword(s):  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Yag Laser ◽  
Laser Sclerostomy

scholarly journals Сorneal endothelium after laser activation of trabecula in patients with primary open-angle glaucoma

2019 ◽  
Author(s):  
Valeria Yashina ◽  
Tatiana Sokolovskaya ◽  
Pavel Volodin
Keyword(s):  
Endothelial Cells ◽  
Laser Radiation ◽  
Confocal Microscopy ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
The State ◽  
Corneal Tissue ◽  
Open Angle ◽  
Corneal Endothelial Cells ◽  
Yag Laser

Laser interventions as microinvasive methods of treatment of patients with primary open-angle glaucoma are widely used in clinical practice because they are effective, safe, the period of rehabilitation after this type of treatment is short, the risk of postoperative complications is minimal. In the scientific literature there are data on the effect of laser radiation on the corneal endothelial cells, that is why this aspect should be investigated in the development and use of new laser technologies in the treatment of patients with primary open-angle glaucoma. One of the most modern methods of corneal examination is known to be lifetime confocal microscopy, which allows to visualize corneal tissue at the cellular level. Purpose: to study the effect of laser radiation on the state of corneal endothelial cells in YAG-laser activation of trabecula in patients with primary open-angle glaucoma. Materials and methods. Sixteen eyes of 15 patients were included in the analysis: 7 men and 8 women aged 53 to 74 years. The mean age of patients was 65.8±5.35 years. All patients underwent YAG-laser activation of trabecula: Nd-YAG laser, 1064nm, 0.8-1.2MJ, 30NS pulse duration, 10-15µm a spot diameter, 55-70 pulses in the circle. In different periods of observation (before laser treatment, 1 hour, 1 week, 1 month, 6 months after laser intervention) the level of IOP was monitored, the state of endothelial corneal cells was studied by confocal microscopy. Results. According to the results of confocal microscopy statistically significant difference between the average density of endothelial cells, polymegathism, and pleomorphism have not been identified. Conclusion. The study did not reveal a negative impact of YAG-laser activation of trabecula on the endothelium of the cornea, which indicates the safety of this technology.

Clinical efficacy of osteopathic correction in the complex treatment of patients with unoperated open-angle glaucoma

2020 ◽  
pp. 97-105
Author(s):  
E. N. Simakova ◽  
O. V. Stenkova
Keyword(s):  
Intraocular Pressure ◽  
Drug Therapy ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Randomized Study ◽  
Main Group ◽  
Control Group ◽  
Open Angle ◽  
Complex Treatment ◽  
Hypotensive Drug

Introduction. Glaucoma is one of the most significant eye diseases. It is often diagnosed, not always amenable to therapy, and can lead to a complete loss of visual functions. In recent years, the method of osteopathic correction has become widespread as one of the effective methods of treatment and rehabilitation of patients with pathologies of various body systems. In the pathogenesis of glaucoma, it is customary to distinguish a dystrophic concept, which considers primary open-angle glaucoma as a result of dystrophic changes in the connective tissue, as well as in the endothelial lining of the trabeculae and Schlemm′s canal, especially destructive changes in mitochondria and the alteration of their functional activity. A vascular concept is also distinguished. According to this concept, the central link in the pathogenesis of glaucoma is circulatory disorder in the ciliary vessels, ocular artery, and major vessels of the head and neck, it can be assumed that osteopathic correction in the treatment of patients with open-angle glaucoma will be pathogenetically substantiated and will have a positive effect on intraocular pressure and trophicity of the optic nerve. The goal of research — to study the influence of in osteopathic correction on the nature of unoperated glaucoma (stage IIA) and to substantiate the possibility of using osteopathic correction in the complex treatment of patients with this pathology.Materials and methods. A prospective controlled randomized study was conducted at 52 city polyclinics, branch 3, Moscow, from January 2018 to January 2019. 40 patients (70 eyes) aged 50 to 75 years with primary open-angle glaucoma IIA stage were examined. At this stage of the disease, patients most often seek medical care and the issue of conservative management is primarily considered. All patients were divided into two groups of 20 people: the main group and the control group. The treatment in the main group included hypotensive drug therapy and osteopathic correction. Patients of the control group received only drug therapy. All patients underwent ophthalmic (visometry, tonometry, perimetry) and osteopathic examination twice: before the treatment and after 3 months.Results. For patients with primary open-angle IIA non-operated glaucoma, regional (most often regions of the head, neck, dura mater) and local (abdominal diaphragm, iliac bones, hip and knee joints) somatic dysfunctions were the most typical. In the main group a statistically significant decrease in the frequency and severity of dysfunctions at all levels was stated. Also, in patients receiving osteopathic correction, a significant decrease in the level of intraocular pressure and perimetric indices was noted. In patients of the control group, no reliable changes in these indicators were obtained.Conclusion. The results obtained indicate that osteopathic correction is clinically effective in the complex treatment of patients with primary open-angle II A glaucoma.

Detection of specific proteins in the aqueous humor in primary open-angle glaucoma

1990 ◽  
Vol 4 (1) ◽  
pp. 1 ◽  
Author(s):  
In Seop Lee ◽  
Young Suk Yu ◽  
Dong Myung Kim ◽  
Dong Ho Youn ◽  
Jin Q Kim
Keyword(s):  
Aqueous Humor ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Specific Proteins
Sign in / Sign up

Export Citation Format

Share Document