Computed tomography of the small bowel in adult celiac disease: the jejunoileal fold pattern reversal

2000 ◽  
Vol 10 (1) ◽  
pp. 119-122 ◽  
Author(s):  
E. Tomei ◽  
M. Marini ◽  
D. Messineo ◽  
F. Di Giovambattista ◽  
M. Greco ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Celiac Disease ◽  
Small Bowel ◽  
Pattern Reversal ◽  
Adult Celiac Disease

Radiographic indicants of adult celiac disease assessed by double-contrast small bowel enteroclysis

1992 ◽  
Vol 15 (2) ◽  
pp. 157-162 ◽  
Author(s):  
Francesco La Seta ◽  
Giuseppe Salerno ◽  
Antonio Buccellato ◽  
Fabio Tine' ◽  
Grazia Furnari
Keyword(s):  
Celiac Disease ◽  
Small Bowel ◽  
Double Contrast ◽  
Adult Celiac Disease

Symptomatic small bowel intussusception: a surgical opportunity to diagnose adult celiac disease?

2004 ◽  
Vol 59 (1) ◽  
pp. 161-162 ◽  
Author(s):  
David S. Sanders ◽  
Iman A.F. Azmy ◽  
San C. Kong ◽  
Frederick K.T. Lee
Keyword(s):  
Celiac Disease ◽  
Small Bowel ◽  
Adult Celiac Disease ◽  
Small Bowel Intussusception

scholarly journals Pearls and Pitfalls in the Diagnosis of Adult Celiac Disease

2008 ◽  
Vol 22 (3) ◽  
pp. 273-280 ◽  
Author(s):  
Hugh J Freeman
Keyword(s):  
Celiac Disease ◽  
Small Bowel ◽  
Tissue Transglutaminase ◽  
Gluten Free Diet ◽  
Screening Tools ◽  
Proximal Jejunum ◽  
Gluten Free ◽  
Pathological Changes ◽  
Specificity And Sensitivity ◽  
Adult Celiac Disease

In adults with diarrhea or suspected malabsorption, a diagnosis of celiac disease requires that two criteria be fulfilled: first, a demonstration of typical pathological changes of untreated disease in biopsies from the proximal small bowel; and second, evidence should exist that clinical (and/or pathological) changes are gluten-dependent, most often as an unequivocal response to a gluten-free diet. Pathological abnormalities of celiac disease may include severe (‘flat’) or variably severe (mild or moderate) small bowel mucosal architectural abnormalities that are associated with both epithelial cell and lymphoid cell changes, including intraepithelial lymphocytosis. Architectural changes tend to be most severe in the duodenum and proximal jejunum and less severe, or absent, in the ileum. These findings, while characteristic of celiac disease, are not specific because several other conditions can produce similar changes. Some serological assays (eg, tissue transglutaminase antibody assays) are very useful screening tools in clinical practice because of their high specificity and sensitivity, but these do not provide a definitive diagnosis. The most critical step in the diagnosis of celiac disease is the demonstration of its gluten-dependent nature. The clinical response to gluten restriction in celiac disease is usually reflected in the resolution of diarrhea and weight gain. Normalization of biopsy changes can be first shown in the most distal intestinal sites of involvement, and later, sometimes only after prolonged periods (months to years) in the duodenum. Rarely, recurrent (or refractory) celiac disease may occur after an initial gluten-free diet response. Finally, some with ‘sprue-like intestinal disease’ cannot be classified because a diet response fails to occur. This may be a heterogeneous group, although some are eventually found to have a malignant lymphoma.

The Correlation Between Pediatric Intussusceptions and Celiac Disease

2019 ◽  
Vol 35 (5) ◽  
pp. 419-424
Author(s):  
Cassidy Paul ◽  
Sharlette Anderson
Keyword(s):  
Computed Tomography ◽  
Celiac Disease ◽  
Small Bowel ◽  
Pericardial Effusion ◽  
Incidental Findings ◽  
Imaging Technique ◽  
Pediatric Population ◽  
Complete Obstruction ◽  
Comprehensive View ◽  
Abdominal Disorder

The most common acute abdominal disorder in the pediatric population appears as a telescoping of the bowel, resulting in either intermittent or complete obstruction. Intussusceptions transpire as the bowel prolapses into a more distal bowel segment and is propelled forward. A case is presented of multiple small bowel intussusceptions, pneumatosis, intraperitoneal fluid, and pericardial effusion. Sonography initially visualized the obstructions, along with multiple other indicators of an abdominal disorder. The use of computed tomography followed to provide a more comprehensive view of the child’s abdomen. Each imaging technique revealed new aspects of the abdominal disorder and concluded in the diagnosis of celiac disease. This case supports the idea that small bowel intussusceptions should not be disregarded as insignificant incidental findings but rather should alert sonographers to further investigate for evidence of celiac disease.

scholarly journals Serological Testing in Screening for Adult Celiac Disease

1999 ◽  
Vol 13 (3) ◽  
pp. 265-269 ◽  
Author(s):  
Helen Rachel Gillett ◽  
Hugh James Freeman
Keyword(s):  
Celiac Disease ◽  
High Risk ◽  
Small Bowel ◽  
Clinical Use ◽  
Serological Testing ◽  
First Line ◽  
Small Bowel Biopsy ◽  
Atypical Symptoms ◽  
Adult Celiac Disease ◽  
Antibody Tests

Assays for celiac-related antibodies are becoming widely available, and the present review aims to clarify the use of these investigations in the diagnosis of, management of and screening for adult celiac disease. The sensitivities and specificities of various antibody tests are discussed, along with their clinical use as an adjunct to small bowel biopsy, and as a first-line investigation for patients with atypical symptoms of celiac disease or patients at high risk of developing sprue.

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