Modulation of lipid phase behavior by kosmotropic and chaotropic solutes

1997 ◽  
Vol 25 (4) ◽  
pp. 261-274 ◽  
Author(s):  
R. Koynova ◽  
J. Brankov ◽  
B. Tenchov
Keyword(s):  
Phase Behavior ◽  
Lipid Phase

Single-Molecule Measurements of the Impact of Lipid Phase Behavior on Anchor Strengths

2005 ◽  
Vol 109 (12) ◽  
pp. 5985-5993 ◽  
Author(s):  
Julie A. Wieland ◽  
Andrew A. Gewirth ◽  
Deborah E. Leckband
Keyword(s):  
Phase Behavior ◽  
Single Molecule ◽  
Lipid Phase ◽  
The Impact

Lipid phase behavior studied with a quartz crystal microbalance: A technique for biophysical studies with applications in screening

2016 ◽  
Vol 145 (20) ◽  
pp. 204904 ◽  
Author(s):  
Astrid Peschel ◽  
Arne Langhoff ◽  
Eva Uhl ◽  
Aruna Dathathreyan ◽  
Susanne Haindl ◽  
...  
Keyword(s):  
Phase Behavior ◽  
Quartz Crystal Microbalance ◽  
Quartz Crystal ◽  
Lipid Phase ◽  
Biophysical Studies

scholarly journals Lipid Phase Behavior and Protein-Lipid Interactions within Nanolipoprotein Particles upon Sol-Gel Derived Encapsulation

2016 ◽  
Vol 110 (3) ◽  
pp. 40a-41a
Author(s):  
Wade F. Zeno ◽  
Silvia L. Hilt ◽  
Subhash H. Risbud ◽  
John C. Voss ◽  
Marjorie L. Longo
Keyword(s):  
Phase Behavior ◽  
Sol Gel ◽  
Lipid Phase ◽  
Lipid Interactions

scholarly journals Solid State Characterization of Dried Liposomes in The Presence of Sucrose and HPMC as Dispersing Matrix

2018 ◽  
Vol 21 (1) ◽  
pp. 16-23
Author(s):  
Nur Aini Mulyadi ◽  
Helmy Yusuf ◽  
Noorma Rosita
Keyword(s):  
Phase Separation ◽  
Solid State ◽  
Phase Behavior ◽  
Pharmaceutical Journal ◽  
Lipid Phase ◽  
Phospholipid Membranes ◽  
Liposome Formulation ◽  
Freeze Dried ◽  
Solid State Characterization

Disaccharides, such as sucrose, have been reported to protect phospholipid membranes during drying, while HPMC is used as gel matrix to inhibit recrystallization. We have investigated the solid state characterization of dried liposome formulation (air-dried and freeze-dried) which was preserved in the presence of sucrose and dispersed in HPMC matrix. The dried liposomal featured cationic dimethyldioctadecylammonium (DDA) was produced to overcome detrimental phase separation in phospholipid membranes during manufacturing process. The effect of sucrose and HPMC on lipid phase behavior during dehydration were characterized including their thermodynamics by DSC, crystallinity by XRD, and liposome structure by SEM. Data revealed that formula contain 5% sucrose and 7.5% HPMC showed a miscible mixture and relatively less crystalline-forming properties that potentially construct a stable dried liposome. The results may aid in the development of dried–DDA liposomal formulation by using combination of sucrose and HPMC.Bangladesh Pharmaceutical Journal 21(1): 16-23, 2018

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