Microbial Metabolism of the Plant Phenolic Compounds Ferulic and Syringic Acids under Three Anaerobic Conditions

1997 ◽  
Vol 33 (3) ◽  
pp. 206-215 ◽  
Author(s):  
C.D. Phelps ◽  
L.Y. Young
Keyword(s):  
Phenolic Compounds ◽  
Microbial Metabolism ◽  
Anaerobic Conditions

Microbial Metabolism of Benzene and the Oxidation of Ferrous Iron under Anaerobic Conditions: Implications for Bioremediation

Anaerobe ◽  
1999 ◽  
Vol 5 (6) ◽  
pp. 595-603 ◽  
Author(s):  
Matthew E Caldwell ◽  
Ralph S Tanner ◽  
Joseph M Suflita
Keyword(s):  
Ferrous Iron ◽  
Microbial Metabolism ◽  
Anaerobic Conditions

Faecal microbial metabolism of olive oil phenolic compounds: In vitro and in vivo approaches

2014 ◽  
Vol 58 (9) ◽  
pp. 1809-1819 ◽  
Author(s):  
Juana I. Mosele ◽  
Sandra Martín-Peláez ◽  
Alba Macià ◽  
Marta Farràs ◽  
Rosa-Maria Valls ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Olive Oil ◽  
Microbial Metabolism

scholarly journals A widely distributed metalloenzyme class enables gut microbial metabolism of host- and diet-derived catechols

2019 ◽  
Author(s):  
Vayu Maini Rekdal ◽  
Paola Nol Bernardino ◽  
Michael U. Luescher ◽  
Sina Kiamehr ◽  
Peter J. Turnbaugh ◽  
...  
Keyword(s):  
Small Molecules ◽  
Molecular Basis ◽  
Distinct Group ◽  
Microbial Metabolism ◽  
Anaerobic Conditions ◽  
Human Gut ◽  
Primary And Secondary Metabolism ◽  
Gut Microorganisms ◽  
Chemical Strategies ◽  
Mediate Metabolism

AbstractCatechol dehydroxylation is a central chemical transformation in the gut microbial metabolism of plant- and host-derived small molecules. However, the molecular basis for this transformation and its distribution among gut microorganisms are poorly understood. Here, we characterize a molybdenum-dependent enzyme from the prevalent human gut bacteriumEggerthella lentathat specifically dehydroxylates catecholamine neurotransmitters available in the human gut. Our findings suggest that this activity enablesE. lentato use dopamine as an electron acceptor under anaerobic conditions. In addition to characterizing catecholamine dehydroxylation, we identify candidate molybdenum-dependent enzymes that dehydroxylate additional host-and plant-derived small molecules. These gut bacterial catechol dehydroxylases are specific in their substrate scope and transcriptional regulation and belong to a distinct group of largely uncharacterized molybdenum-dependent enzymes that likely mediate both primary and secondary metabolism in multiple environments. Finally, we observe catechol dehydroxylation in the gut microbiotas of diverse mammals, suggesting that this chemistry is present in habitats beyond the human gut. Altogether, our data reveal the molecular basis of catechol dehydroxylation among gut bacteria and suggest that the chemical strategies that mediate metabolism and interactions in the human gut are relevant to a broad range of species and habitats.

Anaerobic degradation of some bioflavonoids by microflora of the rumen

1969 ◽  
Vol 15 (8) ◽  
pp. 972-974 ◽  
Author(s):  
F. J. Simpson ◽  
G. A. Jones ◽  
E. A. Wolin
Keyword(s):  
Phenolic Compounds ◽  
Anaerobic Degradation ◽  
Protocatechuic Acid ◽  
Water Soluble ◽  
Anaerobic Conditions ◽  
Bovine Rumen

The microflora of the bovine rumen under anaerobic conditions rapidly degraded bioflavonoids such as rutin, quercitrin, naringin, and hesperidin to water-soluble products. Phloroglucinol was detected as a transitory intermediate in the fermentation of rutin, quercitrin, and naringin, but not hesperidin. Other unknown phenolic compounds were also produced. Protocatechuic acid was decarboxylated to yield catechol, and catechol was not degraded.

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