Subacute and Reproductive Effects in Mink from Exposure to Fusarium fujikuroi Culture Material (M-1214) Containing Known Concentrations of Moniliformin

1998 ◽  
Vol 35 (3) ◽  
pp. 513-517 ◽  
Author(s):  
M. K. Morgan ◽  
S. J. Bursian ◽  
G. E. Rottinghaus ◽  
G. A. Bennett ◽  
J. A. Render ◽  
...  
1997 ◽  
Vol 41 (4) ◽  
pp. 957 ◽  
Author(s):  
R. B. Harvey ◽  
L. F. Kubena ◽  
G. E. Rottinghaus ◽  
J. R. Turk ◽  
H. H. Casper ◽  
...  

1995 ◽  
Vol 74 (2) ◽  
pp. 297-305 ◽  
Author(s):  
D.R. LEDOUX ◽  
A.J. BERMUDEZ ◽  
G.E. ROTTINGHAUS ◽  
J. BROOMHEAD ◽  
G.A. BENNETT

1997 ◽  
Vol 76 (2) ◽  
pp. 265-270 ◽  
Author(s):  
LF Kubena ◽  
RB Harvey ◽  
SA Buckley ◽  
TS Edrington ◽  
GE Rottinghaus

2001 ◽  
Vol 64 (11) ◽  
pp. 1780-1784 ◽  
Author(s):  
ROGER B. HARVEY ◽  
THOMAS S. EDRINGTON ◽  
LEON F. KUBENA ◽  
GEORGE E. ROTTINGHAUS ◽  
JAMES R. TURK ◽  
...  

In two studies, the effects of moniliformin (M)-contaminated diets from Fusarium fujikuroi culture material on growing barrows were evaluated. In the first study, six barrows (three replicates of two each, mean body weight = 17.8 kg) per group (four groups; 24 barrows total) were fed diets calculated to contain 0 mg M/kg feed (control); 25 mg M/kg feed; 50 mg M/kg feed; or 100 mg M/kg feed for 28 days. In the second study, the same experimental design and numbers of barrows (mean body weight = 15.3 kg) were used, and diets were formulated to contain 0 mg M/kg feed (control); 50 mg M/kg feed; 100 mg M/kg feed; or 200 mg M/kg feed. Diets of 100 mg or 200 mg M/kg feed reduced body weight, body weight gain, and feed consumption. Serum biochemical analytes were affected by 100 to 200 mg M/kg feed. Hematologic values were affected by 50, 100, and 200 mg M/kg feed. In the first study, one barrow in the 100 mg M-treated group died, and in the second study, one barrow died in the 100 mg M-treated group, and five barrows died in the 200 mg M-treated group. Relative heart weight was increased in the 200 mg M-treated barrows, yet tissues from organs collected from treatment groups were generally histologically unimpressive. The most consistent sign of M toxicity in barrows appeared to be death induced within 2 to 5 days by 100 to 200 mg M/kg feed.


2002 ◽  
Vol 65 (2) ◽  
pp. 373-377 ◽  
Author(s):  
ROGER B. HARVEY ◽  
THOMAS S. EDRINGTON ◽  
LEON F. KUBENA ◽  
GEORGE E. ROTTINGHAUS ◽  
JAMES R. TURK ◽  
...  

The effects of fumonisin B1 (FB1) from Fusarium verticillioides culture material and moniliformin from Fusarum fujikuroi culture material on growing barrows were evaluated. Four groups of six barrows (three replicates of two each; mean body weight, 11.1 kg) were fed diets containing 0 mg of FB1 and 0 mg of moniliformin per kg of feed (control), 100 mg of FB1 per kg of feed, 100 mg of moniliformin per kg of feed, and 100 mg of FB1 plus 100 mg of moniliformin per kg of feed. Barrows were fed these diets for 28 days. Body weight gain, feed efficiency, serum biochemical analytes, and hematological values were adversely affected by the FB1 and the FB1-plus-moniliformin diets. The moniliformin diet decreased body weight gain. Two barrows in the moniliformin diet group died, and two barrows in the FB1-plus-moniliformin diet group died. All deaths occurred during the first 6 days of the study. Mild to moderate lesions were observed microscopically in heart and lung tissues of the groups fed moniliformin and FB1 plus moniliformin and in liver tissues of the groups fed FB1 and FB1 plus moniliformin. Except for the acute mortality associated with the two diets containing moniliformin, clinical disease induced by the combined feeding of these two mycotoxins appears to be additive or less than additive and due primarily to the toxic expression of FB1.


1999 ◽  
Vol 40 (6) ◽  
pp. 251-256 ◽  
Author(s):  
Susan B. Watson ◽  
Brian Brownlee ◽  
Trevor Satchwill ◽  
E. McCauley

An efficient extraction method is needed to measure trace levels of taste and odour compounds in surface waters. This is usually accomplished by costly and involved analytical procedures. We have developed a simpler alternative, using a commercially available microextraction apparatus (SPME). With this technique we successfully monitored trace levels of some target organoleptics (unsaturated aldehydes e.g. heptadienal, nonadienal, and related compounds) which commonly cause aquatic taste and odour. We identified these compounds in culture material, and analyzed for them during the development of odourous chrysophyte blooms in two ponds. Preliminary work has also found a good recovery of some important off-flavour terpenoids (e.g. geosmin and MIB). SPME is labour and cost efficient, and therefore appealing to water treatment facilities for detection and monitoring. In addition, SPME requires only small sample volumes, and is therefore suitable for culture work.


2012 ◽  
Vol 19 (36) ◽  
pp. 6171-6177 ◽  
Author(s):  
G. Latini ◽  
L. Dipaola ◽  
A. Mantovani ◽  
E. Picano

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