Improved imaging of the spinal cord in multiple sclerosis using three-dimensional fast spin echo

1998 ◽  
Vol 40 (7) ◽  
pp. 416-419 ◽  
Author(s):  
V. L. Stevenson ◽  
I. F. Moseley ◽  
C. C. Phatouros ◽  
D. MacManus ◽  
A. J. Thompson ◽  
...  
Neurology ◽  
1993 ◽  
Vol 43 (12) ◽  
pp. 2632-2632 ◽  
Author(s):  
D. Kidd ◽  
J. W. Thorpe ◽  
A. J. Thompson ◽  
B. E. Kendall ◽  
I. F. Moseley ◽  
...  

2019 ◽  
Vol 60 (4) ◽  
pp. 195-201
Author(s):  
Iman Emad Ahmed ◽  
Hayder Kareem Al-Jaberi ◽  
Mohammed M. Jawad Alkahlissi

Background: The prevalence of spinal cord lesions is high in multiple sclerosis particularly in the cervical cord, and their detection can assist in both the diagnosis and follow-up of the patients. For spinal multiple sclerosis, MRI is considered the first line investigation. Objective: To evaluate the value of sagittal 1.5 Tesla proton density-fast spin echo (PD-FSE) MRI in the detecting and increasing conspicuity of multiple sclerosis lesions in cervical cord in comparison with sagittal T2 fast spin-echo (T2-FSE) MRI. Patients and Methods: A cross sectional study carried out from 3rd of January 2017 to 1st of January 2018 in the MRI department of Al-Imamein Al-Kadhimein Medical City, and included 60 selected patients with a known diagnosis of multiple sclerosis. All patients were examined with 1.5 T sagittal PD-FSE, T2-FSE and axial gradient recalled-echo (GRE) MRI. Results: Sixty patients with cervical multiple sclerosis were enrolled in the study, 146 (100%) lesions were detected by PD-FSE imaging, while T2 detected 105 (71.9%), 41 more lesions (28%) were detected by PD-FSE imaging, (P-value <0.001). All extra lesions were confirmed on axial imaging. In 13 patients (21.6%) one lesion or more had been detected on sagittal PD-FSE imaging while on sagittal T2-FSE imaging, no lesion were detected. On PD-FSE imaging, 17 long lesions were detected in 16 patients (26.7%) while 7 long lesions in 7 patients (11.7%) were detected by T2-FSE imaging. So, in 9 patients (16.7%) 10 lesions were detected as long in PD-FSE while short lesion in T2– FSE, the detection of long lesions by PD-FSE was significantly higher than in T2– FSE (100% vs 71.9% with p- value of 0.002). The mean lesion contrast to cord ratio was significantly higher in PD-FSE as compared to T2-FSE (PD-FSE, 79±2.0, against T2-FSE, 61± 2.6; P-value <0.001). Conclusion: Sagittal proton density was more efficient and more accurate in the detection of cervical cord lesions than sagittal T2-FSE sequence, when used in conjunction with sagittal T2-FSE; it can raise the diagnostic assurance via improving the visualization of the lesions. 


1996 ◽  
Vol 61 (6) ◽  
pp. 632-635 ◽  
Author(s):  
M Filippi ◽  
T A Yousry ◽  
H Alkadhi ◽  
M Stehling ◽  
M A Horsfield ◽  
...  

1994 ◽  
Vol 12 (7) ◽  
pp. 983-989 ◽  
Author(s):  
J.W. Thorpe ◽  
D.G. MacManus ◽  
B.E. Kendall ◽  
P.S. Tofts ◽  
G.J. Barker ◽  
...  

1997 ◽  
Vol 244 (2) ◽  
pp. 119-124 ◽  
Author(s):  
Valerie L. Stevenson ◽  
Mary L. Gawne-Cain ◽  
Gareth J. Barker ◽  
Alan J. Thompson ◽  
D. H. Miller

2012 ◽  
Vol 199 (1) ◽  
pp. 157-162 ◽  
Author(s):  
Nancy Martin ◽  
David Malfair ◽  
Yinshan Zhao ◽  
David Li ◽  
Anthony Traboulsee ◽  
...  

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