Sea Anemone Toxin (ATX II) Modulation of Heart and Skeletal Muscle Sodium Channel α-Subunits Expressed in tsA201 Cells

1996 ◽  
Vol 152 (1) ◽  
pp. 39-48 ◽  
Author(s):  
M. Chahine ◽  
E. Plante ◽  
R.G. Kallen
Keyword(s):  
Skeletal Muscle ◽  
Sodium Channel ◽  
Sea Anemone ◽  
Sea Anemone Toxin ◽  
Α Subunits

The specificity of Av3 sea anemone toxin for arthropods is determined at linker DI/SS2–S6 in the pore module of target sodium channels

2014 ◽  
Vol 463 (2) ◽  
pp. 271-277 ◽  
Author(s):  
Maya Gur Barzilai ◽  
Roy Kahn ◽  
Noa Regev ◽  
Dalia Gordon ◽  
Yehu Moran ◽  
...  
Keyword(s):  
Sodium Channel ◽  
Sodium Channels ◽  
Receptor Site ◽  
Sea Anemone ◽  
Sea Anemone Toxin

A sodium channel determinant that dictates the specificity of Av3 sea anemone toxin for arthropods was identified using channel-swapping experiments and mutagenesis. This finding provides a clue as to the receptor site of Av3 on the sodium channel.

Differential Interaction ofR-Mexiletine with the Local Anesthetic Receptor Site on Brain and Heart Sodium Channel α-Subunits

1999 ◽  
Vol 56 (6) ◽  
pp. 1238-1244 ◽  
Author(s):  
Thomas Weiser ◽  
Yusheng Qu ◽  
William A. Catterall ◽  
Todd Scheuer
Keyword(s):  
Sodium Channel ◽  
Local Anesthetic ◽  
Receptor Site ◽  
Differential Interaction ◽  
Α Subunits

Primary structure of the adult human skeletal muscle voltage-dependent sodium channel

1992 ◽  
Vol 31 (2) ◽  
pp. 131-137 ◽  
Author(s):  
Alfred L. George ◽  
Jeffrey Komisarof ◽  
Roland G. Kallen ◽  
Robert L. Barchi
Keyword(s):  
Skeletal Muscle ◽  
Sodium Channel ◽  
Primary Structure ◽  
Human Skeletal Muscle ◽  
Adult Human ◽  
Voltage Dependent
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