Age-Related Changes in the Biochemical Properties of Human Cancellous Bone Collagen: Relationship to Bone Strength

1999 ◽  
Vol 65 (3) ◽  
pp. 203-210 ◽  
Author(s):  
A. J. Bailey ◽  
T. J. Sims ◽  
E. N. Ebbesen ◽  
J. P. Mansell ◽  
J. S. Thomsen ◽  
...  
1993 ◽  
Vol 53 (S1) ◽  
pp. S41-S46 ◽  
Author(s):  
Thomas J. Beck ◽  
Christopher B. Ruff ◽  
Khem Bissessur

1988 ◽  
Vol 63 (2) ◽  
pp. 154-160 ◽  
Author(s):  
WILLIAM T. SIMONET ◽  
JAMES T. BRONK ◽  
MANUEL R. PINTO ◽  
E. ALAN WILLIAMS ◽  
TIMOTHY H. MEADOWS ◽  
...  

Bone ◽  
2016 ◽  
Vol 83 ◽  
pp. 233-240 ◽  
Author(s):  
Nicolas Vilayphiou ◽  
Stephanie Boutroy ◽  
Elisabeth Sornay-Rendu ◽  
Bert Van Rietbergen ◽  
Roland Chapurlat

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Huayue Chen ◽  
Xiangrong Zhou ◽  
Hiroshi Fujita ◽  
Minoru Onozuka ◽  
Kin-Ya Kubo

The elderly population has substantially increased worldwide. Aging is a complex process, and the effects of aging are myriad and insidious, leading to progressive deterioration of various organs, including the skeleton. Age-related bone loss and resultant osteoporosis in the elderly population increase the risk for fractures and morbidity. Osteoporosis is one of the most common conditions associated with aging, and age is an independent risk factor for osteoporotic fractures. With the development of noninvasive imaging techniques such as computed tomography (CT), micro-CT, and high resolution peripheral quantitative CT (HR-pQCT), imaging of the bone architecture provides important information about age-related changes in bone microstructure and estimates of bone strength. In the past two decades, studies of human specimens using imaging techniques have revealed decreased bone strength in older adults compared with younger adults. The present paper addresses recently studied age-related changes in trabecular and cortical bone microstructure based primarily on HR-pQCT and micro-CT. We specifically focus on the three-dimensional microstructure of the vertebrae, femoral neck, and distal radius, which are common osteoporotic fracture sites.


2009 ◽  
Vol 86 (3) ◽  
pp. 192-201 ◽  
Author(s):  
Marija Djuric ◽  
Danijela Djonic ◽  
Petar Milovanovic ◽  
Slobodan Nikolic ◽  
Robert Marshall ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document