Mutual inhibition between Bötzinger-complex bulbospinal expiratory neurons detected with cross-correlation in the decerebrate rat

1999 ◽  
Vol 125 (4) ◽  
pp. 440-446 ◽  
Author(s):  
G.-F. Tian ◽  
J. H. Peever ◽  
J. Duffin
Keyword(s):  
Cross Correlation ◽  
Mutual Inhibition ◽  
Bötzinger Complex ◽  
Decerebrate Rat ◽  
Expiratory Neurons

Morphology of expiratory neurons of the Bötzinger complex: An HRP study in the cat

1987 ◽  
Vol 258 (4) ◽  
pp. 565-579 ◽  
Author(s):  
Kazuyoshi Otake ◽  
Hiroshi Sasaki ◽  
Hajime Mannen ◽  
Kazuhisa Ezure
Keyword(s):  
Bötzinger Complex ◽  
Expiratory Neurons

Morphological characteristics of augmenting expiratory neurons of the Bötzinger complex

1987 ◽  
Vol 5 ◽  
pp. S20 ◽  
Author(s):  
Kazuyoshi Otake ◽  
Hiroshi Sasaki ◽  
Hajime Mannen ◽  
Kazuhisa Ezure ◽  
Motomu Manabe
Keyword(s):  
Morphological Characteristics ◽  
Bötzinger Complex ◽  
Expiratory Neurons

Cross correlation of medullary expiratory neurons in the cat

1981 ◽  
Vol 73 (2) ◽  
pp. 451-464 ◽  
Author(s):  
Kevin Graham ◽  
James Duffin
Keyword(s):  
Cross Correlation ◽  
Expiratory Neurons

Decrementing expiratory neurons of the Bötzinger complex

1988 ◽  
Vol 72 (1) ◽  
pp. 150-158 ◽  
Author(s):  
M. Manabe ◽  
K. Ezure
Keyword(s):  
Bötzinger Complex ◽  
Expiratory Neurons

scholarly journals Inhibitory control of active expiration by the Bötzinger complex in rats

2019 ◽  
Author(s):  
Karine C. Flor ◽  
William H. Barnett ◽  
Marlusa Karlen-Amarante ◽  
Yaroslav Molkov ◽  
Daniel B. Zoccal
Keyword(s):  
Short Term ◽  
Inhibitory Circuitry ◽  
Respiratory Network ◽  
Bötzinger Complex ◽  
Expiratory Neurons ◽  
Parafacial Respiratory Group ◽  
And Control ◽  
Pharmacological Manipulations ◽  
Sustained Hypoxia

ABSTRACTThe expiratory neurons of the Bötzinger complex (BötC) provide inhibitory inputs to the respiratory network, which, during eupnea, are critically important for respiratory phase transition and duration control. Herein, we investigated how the BötC neurons interact with the expiratory oscillator located in the parafacial respiratory group (pFRG) and control the abdominal activity during active expiration. Using the decerebrated, arterially perfused in situ rat preparations, we recorded the neuronal activity and performed pharmacological manipulations of the BötC and pFRG during hypercapnia or after the exposure to short-term sustained hypoxia – conditions that generate active expiration. The experimental data were integrated in a mathematical model to gain new insights in the inhibitory connectome within the respiratory central pattern generator. Our results reveal a complex inhibitory circuitry within the BötC that provides inhibitory inputs to the pFRG thus restraining abdominal activity under resting conditions and contributing to abdominal expiratory pattern formation during active expiration.

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