Are automatic postural responses in patients with Parkinson's disease abnormal due to their stooped posture?

1999 ◽  
Vol 124 (4) ◽  
pp. 481-488 ◽  
Author(s):  
B. R. Bloem ◽  
Dennis J. Beckley ◽  
J. Gert van Dijk
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Postural Responses ◽  
Stooped Posture ◽  
Automatic Postural Responses

Effect of functional NMDA-antagonist flupirtine on automatic postural responses in Parkinson's disease

2002 ◽  
Vol 249 (7) ◽  
pp. 824-828 ◽  
Author(s):  
Norman Putzki ◽  
Matthias Maschke ◽  
Johannes Drepper ◽  
Hans-Chr. Diener ◽  
Dagmar Timmann
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Nmda Antagonist ◽  
Postural Responses ◽  
Automatic Postural Responses

scholarly journals How to Select Balance Measures Sensitive to Parkinson’s Disease from Body-Worn Inertial Sensors—Separating the Trees from the Forest

Sensors ◽  
2019 ◽  
Vol 19 (15) ◽  
pp. 3320 ◽  
Author(s):  
Naoya Hasegawa ◽  
Vrutangkumar V. Shah ◽  
Patricia Carlson-Kuhta ◽  
John G. Nutt ◽  
Fay B. Horak ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Inertial Sensors ◽  
Objective Measures ◽  
Healthy Controls ◽  
Postural Responses ◽  
Highly Correlated ◽  
Automatic Postural Responses ◽  
Dynamic Posture ◽  
Fold Cross Validation

This study aimed to determine the most sensitive objective measures of balance dysfunction that differ between people with Parkinson’s Disease (PD) and healthy controls. One-hundred and forty-four people with PD and 79 age-matched healthy controls wore eight inertial sensors while performing tasks to measure five domains of balance: standing posture (Sway), anticipatory postural adjustments (APAs), automatic postural responses (APRs), dynamic posture (Gait) and limits of stability (LOS). To reduce the initial 93 measures, we selected uncorrelated measures that were most sensitive to PD. After applying a threshold on the Standardized Mean Difference between PD and healthy controls, 44 measures remained; and after reducing highly correlated measures, 24 measures remained. The four most sensitive measures were from APAs and Gait domains. The random forest with 10-fold cross-validation on the remaining measures (n = 24) showed an accuracy to separate PD from healthy controls of 82.4%—identical to result for all measures. Measures from the most sensitive domains, APAs and Gait, were significantly correlated with the severity of disease and with patient-related outcomes. This method greatly reduced the objective measures of balance to the most sensitive for PD, while still capturing four of the five domains of balance.

Influence of dopaminergic medication on automatic postural responses and balance impairment in Parkinson's disease

1996 ◽  
Vol 11 (5) ◽  
pp. 509-521 ◽  
Author(s):  
Bastiaan R. Bloem ◽  
Dennis J. Beckley ◽  
J. Gert van Dijk ◽  
Aeilko H. Zwinderman ◽  
Michael P. Remler ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Balance Impairment ◽  
Dopaminergic Medication ◽  
Postural Responses ◽  
Automatic Postural Responses

scholarly journals Early Postural Instability in Parkinson’s Disease: A Biomechanical Analysis of the Pull Test

2019 ◽  
Vol 2019 ◽  
pp. 1-11 ◽  
Author(s):  
Javier Ricardo Pérez-Sánchez ◽  
Francisco Grandas
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Healthy Subjects ◽  
Postural Instability ◽  
Biomechanical Analysis ◽  
Stage Iii ◽  
Clinical Test ◽  
Pull Force ◽  
Pull Test ◽  
Postural Responses

Postural instability in Parkinson’s disease (PD) is commonly assessed by the pull test. This clinical test may be biased by the variability of the pull force applied. Our objective was to study the postural responses elicited by reproducible pull forces in healthy subjects and PD patients at different stages of the disease. We performed a multimodal approach that included a systematic analysis of the pull force needed to reach the backward limit of stability (FBLoS) assessed by mechanically produced forces, the displacements of the center of pressure (CoP) recorded on a force platform, and the latencies and patterns of activation of the stabilizing muscles. Comparisons between groups were performed by univariate and multivariate statistical analyses. Sixty-four healthy subjects and 32 PD patients, 22 Hoehn–Yahr (H–Y) stages I-II and 10 H–Y stage III, were studied. In healthy subjects, FBLoS decreased with aging and was lower in females. Mean (SD) FBLoS was 98.1 (48.9) Newtons (N) in healthy subjects, 70.5 (39.8) N in PD patients H–Y stages I-II, and 37.7 (18.9) N in PD patients H–Y stage III. Compared to healthy subjects and when adjusted for age and gender, PD patients H–Y stages I-II exhibited the following: (a) a reduced FBLoS; (b) larger CoP displacements and higher velocities for the same applied force; and (c) combined ankle and hip strategies elicited by less intense pull forces. All of these abnormalities were more pronounced in H–Y stage III PD patients compared to H–Y stages I-II PD patients. In conclusion, patients in the early stages of PD already exhibit a degree of postural instability due to inefficient postural adjustments, and they can more easily be destabilized by small perturbations than healthy subjects. This balance impairment becomes more pronounced in more advanced PD. In the pull test, pull force to step back should be a variable to consider when testing balance in clinical practice.

Beneficial effect of levodopa therapy on stooped posture in Parkinson's disease

2015 ◽  
Vol 42 (3) ◽  
pp. 263-268 ◽  
Author(s):  
Felix Benninger ◽  
Alexander Khlebtovsky ◽  
Yaniv Roditi ◽  
Ofir Keret ◽  
Israel Steiner ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Beneficial Effect ◽  
Levodopa Therapy ◽  
Stooped Posture

Parkinson's disease versus ageing: different postural responses to soleus muscle vibration

2018 ◽  
Vol 65 ◽  
pp. 169-175 ◽  
Author(s):  
Diana Bzdúšková ◽  
Peter Valkovič ◽  
Zuzana Hirjaková ◽  
Jana Kimijanová ◽  
František Hlavačka
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Soleus Muscle ◽  
Muscle Vibration ◽  
Postural Responses

Vestibular induced postural responses in Parkinson's disease

Brain ◽  
1993 ◽  
Vol 116 (5) ◽  
pp. 1177-1190 ◽  
Author(s):  
M. A. Pastor ◽  
B. L. Day ◽  
C. D. Marsden
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Postural Responses

scholarly journals The interaction of postural and voluntary strategies for stability in Parkinson's disease

2012 ◽  
Vol 108 (5) ◽  
pp. 1244-1252 ◽  
Author(s):  
Andrea C. de Lima-Pardini ◽  
Selma Papegaaij ◽  
Rajal G. Cohen ◽  
Luis A. Teixeira ◽  
Beth A. Smith ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
External Perturbation ◽  
Down Low ◽  
Control Subjects ◽  
Healthy Elderly ◽  
Flat Side ◽  
Postural Responses ◽  
Low Constraint ◽  
Hip Flexion

This study assessed the effects of stability constraints of a voluntary task on postural responses to an external perturbation in subjects with Parkinson's disease (PD) and healthy elderly participants. Eleven PD subjects and twelve control subjects were perturbed with backward surface translations while standing and performing two versions of a voluntary task: holding a tray with a cylinder placed with the flat side down [low constraint (LC)] or with the rolling, round side down [high constraint (HC)]. Participants performed alternating blocks of LC and HC trials. PD participants accomplished the voluntary task as well as control subjects, showing slower tray velocity in the HC condition compared with the LC condition. However, the latency of postural responses was longer in the HC condition only for control subjects. Control subjects presented different patterns of hip-shoulder coordination as a function of task constraint, whereas PD subjects had a relatively invariant pattern. Initiating the experiment with the HC task led to 1) decreased postural stability in PD subjects only and 2) reduced peak hip flexion in control subjects only. These results suggest that PD impairs the capacity to adapt postural responses to constraints imposed by a voluntary task.

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