Bone Changes due to Glucocorticoid Application in an Ovariectomized Animal Model for Fracture Treatment in Osteoporosis

2002 ◽  
Vol 13 (5) ◽  
pp. 407-414 ◽  
Author(s):  
C. A. Lill ◽  
C. A. Lill ◽  
U. V. Gerlach ◽  
C. Eckhardt ◽  
J. Goldhahn ◽  
...  
Keyword(s):  
Animal Model ◽  
Fracture Treatment ◽  
Bone Changes ◽  
Ovariectomized Animal

scholarly journals 124 LONGITUDINAL STUDY OF CARTILAGE AND SUBCHONDRAL BONE CHANGES IN A SPONTANEOUS ANIMAL MODEL OF KNEE OA

2011 ◽  
Vol 19 ◽  
pp. S63-S64
Author(s):  
Z. Zamli ◽  
C. Cartwright ◽  
W.A. Cook ◽  
G.E. Torlot ◽  
K. Vassilevskaja ◽  
...  
Keyword(s):  
Animal Model ◽  
Longitudinal Study ◽  
Subchondral Bone ◽  
Knee Oa ◽  
Bone Changes ◽  
Spontaneous Animal Model

scholarly journals Protective Effect of Soy on Movement Disorders Induced by Parkinson Disease in Ovariectomized Animal Model

2013 ◽  
Vol 1 (3) ◽  
pp. 5-10
Author(s):  
Hadi Aligholi ◽  
Maryam Safahani ◽  
Alireza Sarkaki ◽  
Reza Amani ◽  
◽  
...  
Keyword(s):  
Animal Model ◽  
Parkinson Disease ◽  
Protective Effect ◽  
Movement Disorders ◽  
Ovariectomized Animal

The effects of glucosamine hydrochloride on subchondral bone changes in an animal model of osteoarthritis

2007 ◽  
Vol 56 (5) ◽  
pp. 1537-1548 ◽  
Author(s):  
Susanne X. Wang ◽  
Sheila Laverty ◽  
Mircea Dumitriu ◽  
Anna Plaas ◽  
Marc D. Grynpas
Keyword(s):  
Animal Model ◽  
Subchondral Bone ◽  
Glucosamine Hydrochloride ◽  
Bone Changes

Is an anodizing coating associated to the photobiomodulation able to optimize bone healing in ovariectomized animal model?

2021 ◽  
Vol 217 ◽  
pp. 112167
Author(s):  
Tárik Ocon Braga Polo ◽  
Gustavo Antônio Correa Momesso ◽  
William Phillip Pereira Silva ◽  
Anderson Maikon de Souza Santos ◽  
João Matheus Fonseca-Santos ◽  
...  
Keyword(s):  
Animal Model ◽  
Bone Healing ◽  
Ovariectomized Animal

scholarly journals Influence of Simvastatin-Loaded Implants on Osseointegration in an Ovariectomized Animal Model

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Wen Fang ◽  
Shifang Zhao ◽  
Fuming He ◽  
Li Liu ◽  
Guoli Yang
Keyword(s):  
Animal Model ◽  
Bone Formation ◽  
Electrochemical Process ◽  
New Bone Formation ◽  
Bone Implant ◽  
Natural Bone ◽  
Porous Implant ◽  
Bone Implant Contact ◽  
Dose Effects ◽  
Ovariectomized Animal

The success of bone implants in the presence of osteoporosis is limited by lack of osseointegration between the implant and the natural bone. This study applied an electrochemical process to deposit simvastatin-nanohydroxyapatite (HA) coatings on porous implant surfaces and investigated the effects of these simvastatin-HA coatings on implant surfaces in an animal model of osteoporosis. In this study, simvastatin-HA coated implants were inserted into the tibia of osteoporotic rats. After 2, 4, and 12 weeks, tissue was retrieved for histomorphometric evaluation. The results indicated that the simvastatin-HA coatings increased bone-implant contact and new bone formation around implant surfaces. In conclusion, implants loaded with simvastatin by an electrochemical process improved implant osseointegration in osteoporotic rats. Furthermore, the increased concentration of simvastatin could affect the osseointegration, but the dose-effects also need further investigation.

Ultrastructural investigation of spontaneous pituitary gonadotroph cell adenomas in aging Sprague-Dawley rats

1983 ◽  
Vol 41 ◽  
pp. 702-703
Author(s):  
D. J. McComb ◽  
J. Beri ◽  
F. Zak ◽  
K. Kovacs
Keyword(s):  
Electron Microscopy ◽  
Animal Model ◽  
Epoxy Resin ◽  
Immunoelectron Microscopy ◽  
Tumor Type ◽  
Gonadal Function ◽  
Sprague Dawley ◽  
Male And Female ◽  
Reticulin Fibers ◽  
Sprague Dawley Rats

Gonadotroph cell adenomas of the pituitary are infrequent in human patients and are not invariably associated with altered gonadal function. To date, no animal model of this tumor type exists. Herein, we describe spontaneous gonadotroph cell adenomas in old male and female Sprague-Dawley rats by histology, immunocytology and electron microscopy.The material consisted of the pituitaries of 27 male and 38 female Sprague Dawley rats, all 26 months of age or older, removed at routine autopsy. Sections of formal in-fixed, paraffin-embedded tissue were stained with hematoxylin-phloxine-saffron (HPS), the PAS method and the Gordon-Sweet technique for the demonstration of reticulin fibers. For immunostaining, sections were exposed to anti-rat β-LH, anti-ratβ-TSH, anti-rat PRL, anti-rat GH and anti-rat ACTH 1-39. For electron microscopy, tissue was fixed in 2.5% glutaraldehyde, postfixed in 1% OsO4 and embedded in epoxy-resin. Tissue fixed in 10% formalin, embedded in epoxy resin without osmification, was used for immunoelectron microscopy.

Electron Microscopic Detection and Characterization of Nonhuman Primate Enteric Viruses

1982 ◽  
Vol 40 ◽  
pp. 306-307
Author(s):  
G. C. Smith ◽  
R. L. Heberling ◽  
S. S. Kalter
Keyword(s):  
Electron Microscopy ◽  
Animal Model ◽  
Nonhuman Primate ◽  
Clinical Condition ◽  
Intestinal Tract ◽  
Enteric Viruses ◽  
Electron Microscopic ◽  
Microscopic Detection

A number of viral agents are recognized as and suspected of causing the clinical condition “gastroenteritis.” In our attempts to establish an animal model for studies of this entity, we have been examining the nonhuman primate to ascertain what viruses may be found in the intestinal tract of “normal” animals as well as animals with diarrhea. Several virus types including coronavirus, adenovirus, herpesvirus, and picornavirus (Table I) were detected in our colony; however, rotavirus, astrovirus, and calicivirus have not yet been observed. Fecal specimens were prepared for electron microscopy by procedures reported previously.

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