Commencing, Continuing and Stopping Brisk Walking: Effects on Bone Mineral Density, Quantitative Ultrasound of Bone and Markers of Bone Metabolism in Postmenopausal Women

2001 ◽  
Vol 12 (7) ◽  
pp. 581-587 ◽  
Author(s):  
K. Brooke-Wavell ◽  
P. R. M. Jones ◽  
A. E. Hardman ◽  
I. Tsuritani ◽  
Y. Yamada
Keyword(s):  
Bone Mineral Density ◽  
Bone Metabolism ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Quantitative Ultrasound ◽  
Brisk Walking ◽  
Mineral Density

Bone mineral density, quantitative ultrasound parameters and bone metabolism in postmenopausal women with depression

2011 ◽  
Vol 8 (6) ◽  
pp. 485-491 ◽  
Author(s):  
Marco Atteritano ◽  
Antonino Lasco ◽  
Susanna Mazzaferro ◽  
Ida Macrì ◽  
Antonino Catalano ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Metabolism ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Quantitative Ultrasound ◽  
Mineral Density ◽  
Ultrasound Parameters

scholarly journals GIPR rs10423928 and bone-mineral density in postmenopausal women in Shanghai

2022 ◽  
Author(s):  
Lizhi Zhang ◽  
Jinwei He ◽  
Xiang Sun ◽  
Dongyue Pang ◽  
Jingjing Hu ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Femoral Neck ◽  
Gene Polymorphism ◽  
Bone Metabolism ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Mineral Density ◽  
Bone Protection

Our previous studies have demonstrated that there is a correlation between GLP-1R SNP and the BMD in postmenopausal women. GLP-1 and GIP are both incretins. Whether the mutation of GIPR gene affects bone metabolism. SNP rs10423928 is a GIPR gene polymorphism that has been studied more frequently. The aim of this study was to investigate the association between GIPR SNP rs10423928 and bone-mineral density (BMD) in postmenopausal women in Shanghai. The GIPR SNP rs10423928 was detected in 884 postmenopausal women in Shanghai, the correlation between the GIPR SNP and BMD was further assessed. The dominant T/T genotype of the GIPR SNP rs10423928 was significantly related to BMD of the femoral neck (P = 0.035) and Ward’s triangle area (P = 0.033). Our research found that the dominant T/T genotype of GIPR SNP rs10423928 in postmenopausal women is significantly associated with higher BMD. The T/T genotype seems to have bone protection.

scholarly journals Bone mineral density and bone metabolism in postmenopausal women with type 2 diabetes in a Chinese community: a cross-sectional study

2020 ◽  
Author(s):  
Wu Han ◽  
Yufan Zhang ◽  
Wenbin Zhou ◽  
Jing Dai ◽  
Tao Yao ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Type 2 Diabetes ◽  
Bone Formation ◽  
Bone Turnover ◽  
Bone Metabolism ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Mineral Density ◽  
Osteoporosis Fracture

Abstract AMI: There is growing evidence of a complex interaction between T2DM and osteoporosis. The purpose of this study was to further study the relationship between BTMs and fasting blood glucose (FBG) in postmenopausal patients with type 2 diabetes and to analyze the effect of hyperglycemia on bone metabolism. Methods: Six hundred and twelve (612) postmenopausal women were included, including one hundred and seven (107) subjects with T2DM and five hundred and five (505) subjects without diabetes. BMD was measured by DXA (dual-energy X-ray absorptiometry). Markers of bone formation (P1NP) and resorption ( CTX ) were quantified. Results: Compared to controls, postmenopausal women with diabetes had a higher prevalence of previous osteoporosis fracture (27.1% vs. 17.4% for diabetic and nondiabetic women, respectively) and a higher BMD. The P1NP level in women with T2DM was 49.451 ng/ml, while in N-DM individuals, it was 58.633 ng/ml, (p = 0.017). The CTX level in women with T2DM was 0.325 ng/ml, while in N-DM individuals, it was 0.412 ng/ml (p=0.039). In addition, P1NP was significantly negatively associated with age (β=-0.590; p= 0.002) and FBG (β=-1.950; p = 0.035). CTX was negatively associated with FBG (β=-0.029; p = 0.015). Conclusions: T2DM was associated with higher BMD and paradoxically, with an increased risk of fracture. Postmenopausal women with T2DM had lower bone turnover than controls. With increased levels of FBG, bone formation and bone resorption were reduced, and the overall bone turnover level was reduced. Keywords Type 2 diabetes mellitus · Bone mineral density · Bone turnover markers · Osteoporosis fracture

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