Mechanism of action of the nonlipophilic antiallergic drug eclazolast (REV 2871) in the inhibition of mediator release in a mast cell model

1999 ◽  
Vol 48 (11) ◽  
pp. 569-574 ◽  
Author(s):  
M. J. E. Fischer ◽  
N. J. de Mol
Keyword(s):  
Mast Cell ◽  
Mechanism Of Action ◽  
Cell Model ◽  
Mediator Release ◽  
Antiallergic Drug

scholarly journals Searching for tryptase in the RBL-2H3 mast cell model: Preparation for comparative mast cell toxicology studies with zebrafish

2018 ◽  
Vol 39 (3) ◽  
pp. 473-484
Author(s):  
Juyoung K. Shim ◽  
Rachel H. Kennedy ◽  
Lisa M. Weatherly ◽  
Andrew V. Abovian ◽  
Hina N. Hashmi ◽  
...  
Keyword(s):  
Mast Cell ◽  
Cell Model ◽  
Model Preparation

scholarly journals Cryptococcus neoformans – New Science for Discovering Melanin Modifiers

2018 ◽  
pp. 1-4
Author(s):  
R. Soundharya ◽  
V. Aruna ◽  
G. V. Amruthavalli ◽  
R. Gayathri
Keyword(s):  
Cryptococcus Neoformans ◽  
Mechanism Of Action ◽  
Living Cell ◽  
Cell Model ◽  
Cost Effective ◽  
Time Intervals ◽  
New Science ◽  
Biological Tool ◽  
Minimal Media ◽  
Presence And Absence

Aim: The present study was taken up to establish the effect of niacinamide on phenoloxidase lead melanogenesis and to prove the reliability of C. neoformans based screening methodology. Methods: The organism was grown in the Minimal media in presence and absence of L- DOPA and Niacinamide and checked for its pigment producing ability at different time intervals. Results: Niacinamide did not affect the pigmentation in Cryptococcus neoformans in the absence or presence of L-Dopa. Conclusion: Cryptococcus neoformans as a biological tool for studying the mechanism of action of various melanin promoters/ inhibitors. The present study highlights the importance and usefulness of Cryptococcus neoformans based screening invention as it is cost effective rapid and ‘living cell model’.

scholarly journals Bivalent Effect of UV Light on Human Skin Mast Cells—Low-Level Mediator Release at Baseline but Potent Suppression Upon Mast Cell Triggering

2005 ◽  
Vol 124 (2) ◽  
pp. 453-456 ◽  
Author(s):  
Sven Guhl ◽  
Richard Stefaniak ◽  
Marc Strathmann ◽  
Magda Babina ◽  
Helmut Piazena ◽  
...  
Keyword(s):  
Mast Cell ◽  
Mast Cells ◽  
Human Skin ◽  
Uv Light ◽  
Mediator Release ◽  
Low Level

Adenosine-Induced Enhancement of Mast Cell Mediator Release in Asthma and COPD

2000 ◽  
pp. 641-649
Author(s):  
Stephen T. Holgate ◽  
Riccardo Polosa ◽  
William R. Coward ◽  
Martin K. Church
Keyword(s):  
Mast Cell ◽  
Mediator Release ◽  
Mast Cell Mediator ◽  
Mast Cell Mediator Release
Sign in / Sign up

Export Citation Format

Share Document