Ultrastructural Changes in Thyroid Follicular Cells During Normal Postnatal Development and After Infrared Laser Radiation

2000 ◽  
Vol 15 (4) ◽  
pp. 227-237
Author(s):  
L. Vidal ◽  
I. Pérez de Vargas ◽  
G. Mata
Keyword(s):  
Laser Radiation ◽  
Postnatal Development ◽  
Infrared Laser ◽  
Ultrastructural Changes ◽  
Follicular Cells ◽  
Thyroid Follicular Cells

Ultrastructural Changes Caused by Plant Cytokxnins on Dog Thyroid Follicular Cells “In Vitro”

1976 ◽  
Vol 34 ◽  
pp. 174-175
Author(s):  
J. A. Fernandez-Pol
Keyword(s):  
Cyclic Amp ◽  
Ultrastructural Changes ◽  
Follicular Cells ◽  
Animal Cells ◽  
Thyroid Follicular Cells ◽  
In Vitro Response ◽  
Growth Promoting ◽  
Regulatory Effects ◽  
Derivatives Of

Plant cytokinins are a group of growth promoting hormones with pronounced metabolic and regulatory effects not only on plants but also on microbial and animal cells (l). The effects of the N6-substituted derivatives of adenine, especially Zeatin (trans-6-(4-hydroxy-3-methylbut-2-enyl)- aminopurine) and Kinetin (6-furfurylaminopurine) on ultrastructure and on the in vitro response to Thyrotropin (TSH) or 8Br-cyclic AMP were studied in dog thyroid follicular cells.Thyroid slices were incubated in the presence of Zeatin or Kinetin with and without TSH or 8Br-cyclic AMP, after 30min. prior incubation in Earle's solution. Effects on ultrastructure were observed after 30min. to 6hrs. of incubation. The thyroid slices after removal from incubation flasks were fixed immediately in 3%glutaraldehyde-formalin in 0.05M phosphate buffer. Specimens were then treated as described elsewhere (2). Observations were performed with a Siemens IA electron microscope.

Effects of IR laser radiation in thyroid follicular cells: fine structural and stereological study

1993 ◽  
Author(s):  
Lourdes Vidal ◽  
I. Perez de Vargas ◽  
C. Ruiz ◽  
C. Parrado ◽  
A. Pelaez
Keyword(s):  
Laser Radiation ◽  
Follicular Cells ◽  
Ir Laser ◽  
Thyroid Follicular Cells

scholarly journals Ultrastructural changes in the thyroid follicular cells following encephalectomy or hypophysectomy in fetal rats.

1987 ◽  
Vol 49 (3) ◽  
pp. 419-426
Author(s):  
Yasunobu EGUCHI ◽  
Mitsuyuki SHIRAI ◽  
Kazuyoshi ARISHIMA ◽  
Masako YAMAMOTO ◽  
Yasuhiro UEDA
Keyword(s):  
Ultrastructural Changes ◽  
Follicular Cells ◽  
Fetal Rats ◽  
Thyroid Follicular Cells

scholarly journals Thyroid Dysfunction Associated With Follicular Cell Steatosis in Obese Male Mice and Humans

Endocrinology ◽  
2015 ◽  
Vol 156 (3) ◽  
pp. 1181-1193 ◽  
Author(s):  
Min Hee Lee ◽  
Jung Uee Lee ◽  
Kyong Hye Joung ◽  
Yong Kyung Kim ◽  
Min Jeong Ryu ◽  
...  
Keyword(s):  
Thyroid Dysfunction ◽  
Epidemiologic Study ◽  
Fatty Acid Synthetase ◽  
Ultrastructural Changes ◽  
Variable Degree ◽  
Follicular Cells ◽  
Functional Changes ◽  
Pparγ Agonist ◽  
Increased Risk ◽  
Thyroid Follicular Cells

Abstract Adult thyroid dysfunction is a common endocrine disorder associated with an increased risk of cardiovascular disease and mortality. A recent epidemiologic study revealed a link between obesity and increased prevalence of hypothyroidism. It is conceivable that excessive adiposity in obesity might lead to expansion of the interfollicular adipose (IFA) depot or steatosis in thyroid follicular cells (thyroid steatosis, TS). In this study, we investigated the morphological and functional changes in thyroid glands of obese humans and animal models, diet-induced obese (DIO), ob/ob, and db/db mice. Expanded IFA depot and TS were observed in obese patients. Furthermore, DIO mice showed increased expression of lipogenesis-regulation genes, such as sterol regulatory element binding protein 1 (SREBP-1), peroxisome proliferator-activated receptor γ (PPARγ), acetyl coenzyme A carboxylase (ACC), and fatty acid synthetase (FASN) in the thyroid gland. Steatosis and ultrastructural changes, including distension of the endoplasmic reticulum (ER) and mitochondrial distortion in thyroid follicular cells, were uniformly observed in DIO mice and genetically obese mouse models, ob/ob and db/db mice. Obese mice displayed a variable degree of primary thyroid hypofunction, which was not corrected by PPARγ agonist administration. We propose that systemically increased adiposity is associated with characteristic IFA depots and TS and may cause or influence the development of primary thyroid failure.

Fine Structural Alterations in Thyroid Follicular Cells (FC) and Changes in Serum Thyroxine Produced by Feeding Polychlorinated Biphenyl (PCB) to Rats

1977 ◽  
Vol 35 ◽  
pp. 498-499
Author(s):  
W.T. Collins ◽  
Charles C. Capen ◽  
Louis Kasza
Keyword(s):  
Feed Efficiency ◽  
Polychlorinated Biphenyl ◽  
Serum Proteins ◽  
Skin Lesions ◽  
Hepatic Necrosis ◽  
Ultrastructural Changes ◽  
Lymphoid Tissues ◽  
Heat Transfer Fluids ◽  
Thyroid Follicular Cells ◽  
Peripheral Metabolism

The widespread contamination of the environment with PCB, a compound used extensively by industry in hydraulic and heat transfer fluids as well as plasticizers and solvents in adhesives and sealants, has resulted in detectable tissue levels in a large portion of the human population, domestic animals, and wildlife. Intoxication with PCB produces severe hepatic necrosis, degeneration of lymphoid tissues and kidney, skin lesions, decreased reproductive performance, reduced feed efficiency, and decreased weight gain. PCB also has been reported to reduce the binding of thyroid hormone to serum proteins and enhance the peripheral metabolism of thyroxine with increased excretion of thyroxine-glucuronide in the bile (Bastomsky, Endocrinology 95: 1150-1155, 1974).The objectives of this investigation were (1) to investigate the histopathologic, histochemical, and ultrastructural changes in thyroid FC produced by the acute (4 week) and chronic (12 week) administration of low (50 ppm) and high (500 ppm) doses of PCB to rats, (2) to correlate these alterations to changes in serum immunoreactive thyroxine concentration, and (3) to investigate the persistence of the effects of PCB on the thyroid gland.

Ultrastructural changes of the rabbits retina after threshold laser radiation with a wavelength of 532 nm, 577nm and 810 nm

2014 ◽  
Vol 52 (6) ◽  
pp. 89-94
Author(s):  
N. Dumbrova ◽  
◽  
N. Molchanyuk ◽  
T. Romanova ◽  
N. Gavronskaya ◽  
...  
Keyword(s):  
Laser Radiation ◽  
Ultrastructural Changes ◽  
532 Nm

scholarly journals Frustrated tunnel ionization of argon by intense few-cycle infrared laser radiation

2020 ◽  
Vol 1412 ◽  
pp. 092007
Author(s):  
T Pauly ◽  
N Smith ◽  
N Douguet ◽  
K Bartschat
Keyword(s):  
Laser Radiation ◽  
Infrared Laser ◽  
Tunnel Ionization
Sign in / Sign up

Export Citation Format

Share Document