Synthesis, equilibrium swelling, kinetics, permeability and applications of environmentally responsive gels

2005 ◽  
pp. 81-144 ◽  
Author(s):  
Stevin H. Gehrke
Keyword(s):  
Swelling Kinetics ◽  
Environmentally Responsive ◽  
Equilibrium Swelling ◽  
Responsive Gels

scholarly journals Synthesis and characterization of temperature-sensitive and biodegradable hydrogel based on N-isopropylacrylamide

2010 ◽  
Vol 8 (2) ◽  
pp. 426-433 ◽  
Author(s):  
Yueqin Yu ◽  
Yanshun Li ◽  
Chunjing Zhu ◽  
Lingxiu Liu
Keyword(s):  
Enzymatic Degradation ◽  
Molar Ratio ◽  
Solution Temperature ◽  
Swelling Kinetics ◽  
Swelling Ratio ◽  
Nacl Solution ◽  
Equilibrium Swelling ◽  
Cross Linker ◽  
The Cross ◽  
Equilibrium Swelling Ratio

AbstractBased on a biodegradable cross-linker, N-maleyl chitosan (N-MACH), a series of Poly(N-isopropylacrylamide) (PNIPAAm) and Poly(N-isopropylacrylamide-co-acrylamide) [P(NIPAAm-co-Am)] hydrogels were prepared, and their lower critical solution temperature (LCST), swelling kinetics, equilibrium swelling ratio in NaCl solution, and enzymatic degradation behavior in simulated gastric fluids (SGF) were discussed. The LCST did not change with different cross-linker contents. By altering the NIPAAm/Am molar ratio of P(NIPAAm-co-Am) hydrogels, the LCST could be increased to 39°C. The LCST of the hydrogel was significantly influenced by the monomer ratio of the NIPAAm/Am but not by the cross-linker content. In the swelling kinetics, all the dry hydrogels exhibited fast swelling behavior, and the swelling ratios were influenced by the cross-linker content and NIPAAm/Am molar ratios. Equilibrium swelling ratio of all the hydrogels decreased with increasing NaCl solution concentration. In enzymatic degradation tests, the weight loss of hydrogels was dependent on the cross-linker contents and the enzyme concentration.

scholarly journals The effect of saccharides on equilibrium swelling of thermo-responsive gels

RSC Advances ◽  
2020 ◽  
Vol 10 (51) ◽  
pp. 30723-30733
Author(s):  
A. D. Drozdov ◽  
J. deClaville Christiansen
Keyword(s):  
Phase Transition ◽  
Aqueous Solutions ◽  
Mechanical Response ◽  
Volume Phase Transition ◽  
Volume Phase ◽  
Equilibrium Swelling ◽  
Responsive Gels

A model is developed for the mechanical response and equilibrium swelling of thermo-responsive gels and applied to the analysis of their volume phase transition in aqueous solutions of saccharides.

Effect of Salinity and Temperature on Swelling Behavior of Nano/Micro Polymer Particle

2013 ◽  
Vol 448-453 ◽  
pp. 3993-3997
Author(s):  
Yu Lou ◽  
Wei Yao Zhu ◽  
Xue Ling Zhang ◽  
Yun Qian Long
Keyword(s):  
Oil Recovery ◽  
Polymer Particle ◽  
Swelling Behavior ◽  
Swelling Kinetics ◽  
Swelling Ratio ◽  
Polymer Particles ◽  
Equilibrium Swelling ◽  
Swelling Characteristics ◽  
Equilibrium Swelling Ratio ◽  
Kinetics Of

Nano/micro polymer particles of acrylamide (AM), acrylic acid (AA), methyl methacrylate (MMA) are used to enhance oil recovery. Swelling kinetics of nano/micro polymer particles were investigated through experimental analysis and statistical analysis. The effect of salinity and temperature on swelling behavior over time is studied experimentally. The swelling kinetics of nano/micro polymer particle was described by second order kinetics. Equilibrium swelling ratio and swelling rate were obtained through nonlinear regression. The quantitative relationships between equilibrium swelling ratio and salinity, temperature were presented. Results show that the swelling ratio increases with increasing temperature or decreasing salt concentration. The study provides a direct perspective of swelling characteristics of nano/micro polymer particles for oil recovery enhancement.

scholarly journals Synthesis of Novel Tamarind Gum-co-Poly(Acrylamidoglycolic Acid) based pH Responsive semi-IPN Hydrogels and their Ag Nanocomposites for Controlled Release of Chemotherapeutics and Inactivation of Multi Drug Resistance Bacteria

2021 ◽  
Author(s):  
Kasula Nagaraja ◽  
Kummari S.V. Krishna Rao ◽  
Sunmi Zo ◽  
Sung Soo Han ◽  
Madhusudana Rao Kummara
Keyword(s):  
Drug Delivery ◽  
Pathogenic Bacteria ◽  
Hct116 Cell ◽  
Swelling Behavior ◽  
Cancer Drug ◽  
Multi Drug Resistance ◽  
Swelling Kinetics ◽  
Klebsiella Pneumonia ◽  
Ph Responsive ◽  
Equilibrium Swelling

Novel pH responsive semi-interpenetrating polymer hydrogels based on tamarind gum-co-poly(acrylamidoglycolic acid) (TMGA) polymers have been synthesized using simple free radical polymerization in the presence of bis[2-(methacryloyloxy)ethyl] phosphate as a crosslinker and potassium persulfate as a initiator. In addition, these hydrogels have been used as templates for green synthesis of silver nanoparticles (13.4±3.6 nm in diameter, TMGA-Ag) by using leaf extract of Teminalia bellirica as reducing agent. Swelling kinetics and equilibrium swelling behavior of the TMGA hydrogels have been investigated in various pH environment the maxium % equilibrium swelling behavior observed i.e., 2882±1.2. The synthesized hydrogels and silver nanocomposites have been characterized by the UV, FTIR, XRD, SEM and TEM. TMGA and TMGA-Ag hydrogels have been investigated to study the characteristics of drug delivery and antimicrobial study. Doxorubicin hydrochloride, a chemotherapeutic agent successfully encapsulated with maximum encapulstaion efficiency i.e., 69.20±1.2 and performed in vitro release studies in pH physiological and gastric environment at 37 ℃. The drug release behavior is examined with kinetic models such as zero order, first order, Higuchi, Hixson Crowell, Korsmeyer-Peppas. These release data was the best fitted with the Korsemeyer-Peppas transport mechanism with n=0.91. Treatment effect on HCT116 Cell, human colon cancer cells were assessed with cell viability and cell cycle analysis. Antimicrobial activity of TMGA-Ag hydrogels is studied against to Staphylococcus aureus and Klebsiella pneumonia. Finally, the results demonstrate that TMGA and TMGA-Ag are promising candidates for anti-cancer drug delivery and inactivation of pathogenic bacteria, respectively.

scholarly journals Synthesis of Novel Tamarind Gum-co-poly(acrylamidoglycolic acid)-Based pH Responsive Semi-IPN Hydrogels and Their Ag Nanocomposites for Controlled Release of Chemotherapeutics and Inactivation of Multi-Drug-Resistant Bacteria

Gels ◽  
2021 ◽  
Vol 7 (4) ◽  
pp. 237
Author(s):  
Kasula Nagaraja ◽  
Kummari S. V. Krishna Rao ◽  
Sunmi Zo ◽  
Sung Soo Han ◽  
Kummara Madhususdana Rao
Keyword(s):  
Drug Delivery ◽  
Pathogenic Bacteria ◽  
In Vitro Release ◽  
Swelling Behavior ◽  
Cancer Drug ◽  
Resistant Bacteria ◽  
Swelling Kinetics ◽  
Klebsiella Pneumonia ◽  
Ph Responsive ◽  
Equilibrium Swelling

In this paper, novel pH-responsive, semi-interpenetrating polymer hydrogels based on tamarind gum-co-poly(acrylamidoglycolic acid) (TMGA) polymers were synthesized using simple free radical polymerization in the presence of bis[2-(methacryloyloxy)ethyl] phosphate as a crosslinker and potassium persulfate as a initiator. In addition, these hydrogels were used as templates for the green synthesis of silver nanoparticles (13.4 ± 3.6 nm in diameter, TMGA-Ag) by using leaf extract of Teminalia bellirica as a reducing agent. Swelling kinetics and the equilibrium swelling behavior of the TMGA hydrogels were investigated in various pH environments, and the maximum % of equilibrium swelling behavior observed was 2882 ± 1.2. The synthesized hydrogels and silver nanocomposites were characterized via UV, FTIR, XRD, SEM and TEM. TMGA and TMGA-Ag hydrogels were investigated to study the characteristics of drug delivery and antimicrobial study. Doxorubicin hydrochloride, a chemotherapeutic agent successfully encapsulated with maximum encapsulation efficiency, i.e., 69.20 ± 1.2, was used in in vitro release studies in pH physiological and gastric environments at 37 °C. The drug release behavior was examined with kinetic models such as zero-order, first-order, Higuchi, Hixson Crowell and Korsmeyer–Peppas. These release data were best fitted with the Korsemeyer–Peppas transport mechanism, with n = 0.91. The effects of treatment on HCT116 human colon cancer cells were assessed via cell viability and cell cycle analysis. The antimicrobial activity of TMGA-Ag hydrogels was studied against Staphylococcus aureus and Klebsiella pneumonia. Finally, the results demonstrate that TMGA and TMGA-Ag are promising candidates for anti-cancer drug delivery and the inactivation of pathogenic bacteria, respectively.

Evaluation of CO2-triggered and thermo-responsive gels for heterogeneous oil formations

2021 ◽  
Vol 622 ◽  
pp. 126688
Author(s):  
Ronald Nguele ◽  
Brian Adala Omondi ◽  
Soichiro Yamasaki ◽  
Shusaku Mandai ◽  
Yuichi Sugai ◽  
...  
Keyword(s):  
Responsive Gels
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