GOOD RESULTS WITH ANABOLIC STEROIDS FOR APLASTIC ANAEMIA

InPharma ◽  
1979 ◽  
Vol 197 (1) ◽  
pp. 8-8
Keyword(s):  
Aplastic Anaemia ◽  
Anabolic Steroids

APLASTIC ANAEMIA TREATED WITH ANABOLIC STEROIDS

1979 ◽  
Vol 43 (3) ◽  
pp. 483-484 ◽  
Author(s):  
Robert Peter Gale ◽  
C. Haanen
Keyword(s):  
Aplastic Anaemia ◽  
Anabolic Steroids

Androgenic hormones in anaemia

1964 ◽  
Vol 2 (19) ◽  
pp. 75-76
Keyword(s):  
Breast Cancer ◽  
Aplastic Anaemia ◽  
Anabolic Steroids ◽  
Male Hypogonadism ◽  
Medical Letter ◽  
The Many

Despite the many claims made (see Medical Letter, Brit. ed. 1962, 1, 38), androgens and the anabolic steroids related to them have been shown to be of value only in male hypogonadism, in breast cancer in women after the menopause and in some patients with myelofibrosis and aplastic anaemia.

The Treatment of Aplastic Anaemia with Anabolic Steroids

1962 ◽  
Vol 51 (2) ◽  
pp. 201-208 ◽  
Author(s):  
MOSTAFA KHALIL ◽  
ABDEL-HADl IBRAHIM
Keyword(s):  
Aplastic Anaemia ◽  
Anabolic Steroids

Acquired Aplastic Anaemia in Children Treated with Corticosteroids and Anabolic Steroids

2009 ◽  
Vol 26 (3) ◽  
pp. 195-201
Author(s):  
Göran Gustafsson ◽  
Anders Kreuger ◽  
Stig Sjölin
Keyword(s):  
Aplastic Anaemia ◽  
Anabolic Steroids

Who needs anabolic steroids?

1979 ◽  
Vol 17 (14) ◽  
pp. 54-56
Keyword(s):  
Renal Failure ◽  
Weight Gain ◽  
Aplastic Anaemia ◽  
Strong Evidence ◽  
Anabolic Steroids ◽  
Nitrogen Retention ◽  
Induce Weight Gain ◽  
Do So

Anabolic steroids are synthetic androgens which produce nitrogen retention1 and have a weak masculinising effect.2 They have been used to induce weight gain, increase strength, shorten convalescence and reduce debility but there is little evidence that they do so. More specific indications have included their use to promote growth, and for the treatment of renal failure, aplastic anaemia and osteoporosis. Because of the substantial risks associated with these drugs, it is important that their uses be supported by strong evidence.

scholarly journals A Unique Constitutional Robertsonian Translocation t(13;14) Associated with Severe Aplastic Anaemia

2021 ◽  
Author(s):  
Bhupendra Singh ◽  
Aparajita Singh Chauhan ◽  
Shailendra Prasad Verma ◽  
Anil Kumar Tripathi ◽  
Swasti Sinha
Keyword(s):  
Bone Marrow ◽  
Aplastic Anaemia ◽  
Robertsonian Translocation ◽  
Anabolic Steroids ◽  
Final Diagnosis ◽  
Severe Aplastic Anaemia ◽  
Packed Red Blood Cells ◽  
Therapeutic Implications ◽  
Unstimulated Culture ◽  
Hypoplastic Marrow

Aplastic anaemia is characterised by cytopenias and hypocellular bone marrow without any evidence of marrow fibrosis or marrow infiltration. There is no specific cytogenetic abnormality associated with aplastic anaemia. Most common abnormalities are trisomies of chromosome 6, 8 and loss of 7. A 17-year-old female, presented with generalised weakness, exertional breathlessness and menorrhagia for last six months. She also gave a history of 12 units Packed Red Blood Cells (PRBC) transfusion, at the rate of 2-3 units per month in the last five months. Routine haematology showed severe pancytopenia with reticulocytopenia. Bone marrow evaluation revealed hypoplastic marrow with 15% bone marrow cellularity suggesting aplastic anaemia. Karyotyping using Giemsa (GTG) banding of unstimulated culture showed a very unique constitutional Robertsonian Translocation (RT) karyotype 45+XX, der(13;14)(q10;q10). Patient responded partially to treatment with cyclosporine and anabolic steroids. The final diagnosis was severe aplastic anaemia associated with constitutional RT t(13;14) karyotype. Although cytogenetic abnormalities are neither common nor specific in aplastic anaemia, some of them can have diagnostic and therapeutic implications.

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