Potassium Supplementation in Hypertension

InPharma ◽  
1985 ◽  
Vol 513 (1) ◽  
pp. 3-3
Keyword(s):  
Potassium Supplementation

scholarly journals Diabetic Ketoacidosis Management and Treatment Outcome at Medical Ward of Shashemene Referral Hospital, Ethiopia: A Retrospective Study

2021 ◽  
Vol 14 ◽  
pp. 117955142110049
Author(s):  
Getu Melesie Taye ◽  
Amente Jorise Bacha ◽  
Fetene Abeje Taye ◽  
Mohammed Hussen Bule ◽  
Gosaye Mekonen Tefera
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Treatment Outcome ◽  
Hospital Mortality ◽  
Medical Ward ◽  
Inclusion Criteria ◽  
Potassium Supplementation ◽  
Poor Treatment ◽  
Poor Treatment Outcome ◽  
Concurrent Medication

Background: Diabetic Ketoacidosis (DKA) is the most common and yet potentially life-threatening acute complication of diabetes that progresses rapidly to death and requires immediate medical intervention. Objective: To assess the DKA management and treatment outcome/in-hospital mortality and its predictors among hospitalized patients with DKA at the Medical ward of Shashemene Referral Hospital (SRH). Method: A retrospective study was conducted at the Medical Ward of SRH from 01 February 2015 to 31 January 2017. A systematic random sampling technique was used to select study subjects based on the inclusion criteria. Thus, of 236 reviewed charts, only 225 patients with DKA fulfilled inclusion criteria. Treatment outcome was considered good for patients who have shown improvement at discharge, while poor for patients who left against medical advice or died in the hospital. Logistic regression analysis was done to determine independent predictors for treatment outcome/in-hospital mortality using SPSS version 20 with statistical significant at P ⩽ .05. Results: Of 225 patients with DKA, 124 (55.1%) were male. Regular insulin was prescribed to all patients and antibiotics were administered to 87 (38.7%). Potassium supplementation was given only for 28 (12.4%). Non-adherence to insulin treatment (n = 91; 40.4%) and infection (n = 66; 29.3%) were the principal DKA precipitating factors. Even though 73.8% of hospitalized patients with DKA have shown good treatment outcomes, DKA contributed 12% in-hospital mortality. The result of multivariate logistic regression analysis shown that hypoglycemia is the only independent predictor for in-hospital mortality[ P = .03]. Moreover, the independent predictors for poor DKA treatment outcome were found to be smoker [ P = .04], Urinary tract infection (UTI) relative to other co-morbid condition [ P < .001], severe hypokalemia which increase risk of poor treatment outcome by around 4 times [ P = .02], and use of Metronidazole as a concurrent medication relative to other concurrent medication [ P = .03]. Conclusion: There was a high in-hospital mortality rate due to correctable causes. This mortality is unacceptable as it was majorly related to the poor practice of potassium supplementation and hypoglycemia due to insulin. Thus, clinicians and stakeholders should have to focus on modifiable factors (hypokalemia, UTI, and hypoglycemia) to reduce poor treatment outcome/in-hospital mortality.

scholarly journals MICRONUTRIENT CONTENTS IN THE PROFILE OF A RECOVERED SOIL WITH SEWAGE SLUDGE AND NATIVE SPECIES OF ATLANTIC FOREST

FLORESTA ◽  
2019 ◽  
Vol 49 (3) ◽  
pp. 485
Author(s):  
Lívia Mara Lima Goulart ◽  
Marianne Fidalgo de Faria ◽  
Grasiela Spada ◽  
Thiago Tássio de Souza Silva ◽  
Iraê Amaral Guerrini
Keyword(s):  
Sewage Sludge ◽  
Atlantic Forest ◽  
Soil Profile ◽  
Native Species ◽  
Control Treatment ◽  
Mineral Fertilization ◽  
Promising Alternative ◽  
Final Destination ◽  
Potassium Supplementation

The use of sewage sludge in agriculture and recovery of degraded areas has been shown as a promising alternative for its final destination. Studies on micronutrient levels after sludge application are necessary to avoid soil contamination at toxic levels. The objective of this work was to verify the micronutrient contents in the soil profile and pH, up to one-meter-deep, nine years after the application of sewage sludge and planting of native species of the Atlantic Forest. The experiment was implemented in a degraded Quartzeneic Neosol and conducted in randomized blocks with four replicates and eight treatments, consisting of six doses of sewage sludge (0, 2.5, 5, 10, 15 and 20 Mg ha-1, with supplementation of potassium due to low concentration in the residue), besides the control treatment, mineral fertilization and only potassium supplementation. After nine years, the contents of all micronutrients evaluated presented a significant response to the application of the treatments, and the application of sewage sludge provided an increase in their contents. Soil pH remained stable at sites receiving mineral fertilization and potassium supplementation. Only manganese and zinc showed mobility in the soil profile. The application of sewage sludge in degraded soil increases the micronutrient content and decreases its movement in the soil profile, and the application of the maximum dose of the residue does not provide toxic levels of these elements in the soil in the long term.

scholarly journals Potassium supplementation ameliorates mineralocorticoid-induced sodium retention

1993 ◽  
Vol 43 (5) ◽  
pp. 1097-1103 ◽  
Author(s):  
G. Gopal Krishna ◽  
Shiv C. Kapoor
Keyword(s):  
Sodium Retention ◽  
Potassium Supplementation

scholarly journals Carryover effects of potassium supplementation on calcium homeostasis in dairy cows at parturition

2010 ◽  
Vol 93 (5) ◽  
pp. 2119-2129 ◽  
Author(s):  
M.S. Bhanugopan ◽  
W.J. Fulkerson ◽  
D.R. Fraser ◽  
M. Hyde ◽  
D.M. McNeill
Keyword(s):  
Dairy Cows ◽  
Calcium Homeostasis ◽  
Carryover Effects ◽  
Potassium Supplementation

Abstract P184: Effects of Sodium and Potassium Supplementation on Blood Pressure and Arterial Stiffness in Untreated (Pre)Hypertensives on a Low-Sodium, Low-Potassium Diet

Circulation ◽  
2014 ◽  
Vol 129 (suppl_1) ◽  
Author(s):  
Lieke Gijsbers ◽  
James Dower ◽  
Marco Mensink ◽  
Johanna M Geleijnse
Keyword(s):  
Blood Pressure ◽  
Arterial Stiffness ◽  
Random Order ◽  
Potassium Intake ◽  
Low Sodium ◽  
Potassium Supplementation ◽  
Urinary Potassium ◽  
Low Potassium ◽  
Sodium And Potassium ◽  
Sodium Supplementation

Introduction: We performed a 12-week randomized placebo-controlled crossover study to examine the effects of sodium and potassium supplementation on blood pressure (BP) and arterial stiffness in untreated (pre)hypertensive individuals on a low-sodium, low-potassium diet. Methods: During the study, subjects were on a fully controlled diet that provided on average 2.4 g/d of sodium (equals 6 g/d of salt) and 2.2 g/d of potassium. After a 1-week run-in period, 37 subjects received capsules with supplemental sodium (3 g/d, equals 7.5 g/d of salt), supplemental potassium (3 g/d), or placebo, for four weeks each (not separated by wash-out), in random order. Fasting office BP, 24-h ambulatory BP, and measures of arterial stiffness (SphygmoCor®) were assessed at baseline and after each treatment. Results: Subjects had a mean pre-treatment BP of 145/81 mmHg and 68% (25 of 37) had systolic BP (SBP) ≥140 mmHg. In 36 subjects who completed the study, sodium supplementation increased urinary sodium by 97.6 mmol/24h (2.2 g/d) and potassium supplementation increased urinary potassium by 62.9 mmol/24h (2.5 g/d), compared to placebo (Table). Sodium supplementation significantly increased office BP by 7.5/3.3 mmHg, 24-h BP by 7.0/2.1 mmHg and central BP by 8.5/3.6 mmHg. Potassium supplementation significantly reduced 24-h BP by 4.0/1.7 mmHg. Measures of arterial stiffness did not change. Conclusion: Increasing the intake of sodium has a strong adverse effect on BP in untreated (pre)hypertensive individuals. Increased potassium intake, however, lowers BP even when people are on a reduced sodium diet. Short-term changes in sodium and potassium intake have little effect on arterial stiffness. Trial registration: ClinicalTrials.gov Identifier: NCT01575041

scholarly journals Feline primary hyperaldosteronism: an emerging endocrine disease

2016 ◽  
Vol 46 (4) ◽  
pp. 686-693 ◽  
Author(s):  
Daniel Diola Bento ◽  
Fabíola Soares Zahn ◽  
Laura Carolina Duarte ◽  
Luiz Henrique de Araújo Machado
Keyword(s):  
Water Retention ◽  
Clinical Findings ◽  
Primary Hyperaldosteronism ◽  
Aldosterone Secretion ◽  
Aldosterone Antagonists ◽  
Endocrine Disease ◽  
Potassium Supplementation ◽  
Unilateral Disease ◽  
Appropriate Therapy ◽  
Pendulous Abdomen

ABSTRACT: The primary hyperaldosteronism, an endocrine disease increasingly identified in cats, is characterized by adrenal gland dysfunction that interferes with the renin-angiotensin-aldosterone system, triggering the hypersecretion of aldosterone. Pathophysiological consequences of excessive aldosterone secretion are related to increased sodium and water retention, and increased excretion of potassium, which induce hypertension and severe hypokalemia, respectively. The most common clinical findings in cats include: polydipsia, nocturia, polyuria, generalized weakness, neck ventroflexion, syncope, anorexia, weight loss, pendulous abdomen and blindness. Diagnosis is based on the evidence of hormonal hypersecretion with suppression of renin release, imaging and histopathological evaluation of adrenal glands. Treatment may be curative with adrenalectomy, in cases of unilateral disease, or conservative, through administration of aldosterone antagonists, potassium supplementation and antihypertensives. Prognosis varies from fair to good with the appropriate therapy. This article reviews the main aspects of primary aldosteronism in cats, providing the clinician with important information for the diagnosis of this disease.

Potassium Supplementation, Diet vs Pills

CHEST Journal ◽  
2004 ◽  
Vol 125 (2) ◽  
pp. 404-409 ◽  
Author(s):  
Wendi Norris ◽  
Karyn S. Kunzelman ◽  
Susan Bussell ◽  
Linda Rohweder ◽  
Richard P. Cochran
Keyword(s):  
Potassium Supplementation
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