Maintenance of genetic variation and moderate differentiation among populations under sex-biased dispersal in the common voleMicrotus arvalis in patchy habitats

2010 ◽  
Vol 55 (4) ◽  
pp. 333-341
Author(s):  
Anetta Borkowska ◽  
Mirosław Ratkiewicz ◽  
Maarit Jaarola
2004 ◽  
Vol 33 (1) ◽  
pp. 186-196 ◽  
Author(s):  
Jaime García-Moreno ◽  
Adolfo G. Navarro-Sigüenza ◽  
A. Townsend Peterson ◽  
Luis A. Sánchez-González

2021 ◽  
Vol 288 (1947) ◽  
Author(s):  
Erin E. Shortlidge ◽  
Sarah B. Carey ◽  
Adam C. Payton ◽  
Stuart F. McDaniel ◽  
Todd N. Rosenstiel ◽  
...  

The evolution of sustained plant–animal interactions depends critically upon genetic variation in the fitness benefits from the interaction. Genetic analyses of such interactions are limited to a few model systems, in part because genetic variation may be absent or the interacting species may be experimentally intractable. Here, we examine the role of sperm-dispersing microarthropods in shaping reproduction and genetic variation in mosses. We established experimental mesocosms with known moss genotypes and inferred the parents of progeny from mesocosms with and without microarthropods, using a pooled sequencing approach. Moss reproductive rates increased fivefold in the presence of microarthropods, relative to control mesocosms. Furthermore, the presence of microarthropods increased the total number of reproducing moss genotypes, and changed the rank-order of fitness of male and female moss genotypes. Interestingly, the genotypes that reproduced most frequently did not produce sporophytes with the most spores, highlighting the challenge of defining fitness in mosses. These results demonstrate that microarthropods provide a fitness benefit for mosses, and highlight the potential for biotic dispersal agents to alter fitness among moss genotypes.


1977 ◽  
Vol 15 (9-10) ◽  
pp. 833-846 ◽  
Author(s):  
Mahmud Ahmad ◽  
D. O. F. Skibinski ◽  
J. A. Beardmore

2020 ◽  
Vol 18 (3) ◽  
pp. 165-171
Author(s):  
Ling Du ◽  
Lina Wang ◽  
Tong Yu ◽  
Ruolei Xin ◽  
Zhefeng Meng

Background: HIV-1 CRF01_AE and CRF07_BC recombinant strains are responsible for more than 80% of new infections in China since the beginning of the 2000s. These two strains may have distinct genetic mutations, which resulted in distinct patterns of pathogenesis related to the viral gene, Vpr. Objective: The amino acid pattern and genetic diversity of Vpr were analyzed and characterized in HIV-1 CRF01_AE and CRF07_BC HIV-1 strains. Methods: The Vpr gene was amplified from extracted viral RNA and DNA sequencing was performed using an ABI3730 analyzer. The positional amino acid composition, genetic variation and distance of Vpr sequence were analyzed by Bio-Edit 7.2 and Mega 6.01 software packages. Results: A total of 162 CRF01_AE and 80 CRF07_BC derived Vpr sequences were obtained by DNA sequencing. CRF01_AE patients showed higher viral load and lower CD4 counts than CRF07_BC patients (P<0.05). Higher genetic distance and more polymorphic amino acids were found in CRF01_AE Vpr than CRF07_BC Vpr (P<0.05). The common conservative amino acid region was identified as 29EAVRHFP35 in both CRF07_BC and CRF01_AE. Of note, the R77Q mutation was found in both the most recently Chinese derived CRF07_BC and CRF01_AE Vpr. Conclusion: CRF01_AE derived Vpr has higher genetic variation and pathogenesis in comparison to the CRF07_BC strain.


2000 ◽  
Vol 3 (1) ◽  
pp. 39-44 ◽  
Author(s):  
ROBERT A. HEGELE ◽  
HENIAN CAO ◽  
STEWART B. HARRIS ◽  
BERNARD ZINMAN ◽  
ANTHONY J. HANLEY ◽  
...  

Hegele, Robert A., Henian Cao, Stewart B. Harris, Bernard Zinman, Anthony J. Hanley, and Carol M. Anderson. Genetic variation in LMNA modulates plasma leptin and indices of obesity in aboriginal Canadians. Physiol Genomics 3: 39–44, 2000.—We previously showed that a rare mutation in LMNA, which encodes lamins A and C, underlies autosomal dominant Dunnigan-type familial partial lipodystrophy (FPLD). Because FPLD is an extreme example of genetically disturbed adipocyte differentiation, it is possible that common variation in LMNA is associated with obesity-related phenotypes. We therefore analyzed the relationships between the common LMNA 1908T/C single nucleotide polymorphism (SNP) and plasma leptin and anthropometric indices in 306 nondiabetic Canadian Oji-Cree. We found that subjects with the LMNA 1908T/1908T genotype had significantly higher plasma leptin than the subjects with either the 1908C/1908T or 1908C/1908C genotypes, after adjustment for age and sex. Physical indices of obesity, such as body mass index, percent body fat, and ratio of waist-to-hip circumference, were also higher among Oji-Cree subjects with the LMNA 1908T/1908T genotype than the subjects with either the 1908C/1908T or 1908C/1908C genotypes. The results suggest that common genetic variation in LMNA may be an important determinant of plasma leptin and obesity-related quantitative traits.


Aquaculture ◽  
1975 ◽  
Vol 5 (4) ◽  
pp. 375-387 ◽  
Author(s):  
G. Wohlfarth ◽  
R. Moav ◽  
G. Hulata ◽  
A. Beiles

2015 ◽  
Vol 16 (2) ◽  
pp. 118
Author(s):  
Pramudji Hastuti ◽  
Abdul Salam Mudzakir Sofro ◽  
Ahmad Husain Asdie ◽  
Ahmad Hamim Sadewa

Apolipoprotein E (ApoE) has been considered to play an important role in cardiovascular disorders.Several studies reported that genetic variation in ApoE locus influence plasma lipoprotein level. The objectivesof this study was to compare the frequency of ApoE genotypes and alleles in some populations of Indonesia.One hundred and ninety five voluntarily unrelated apparently healthy individuals were recruited fromSurabaya, Palu and Alor representing the western, middle and eastern populations of Indonesia, respectively.Blood samples were collected from each subject for DNA extraction. The common allelic variants of ApoE werescreened using polymerase chain reaction (PCR) and restriction fragment length polymorphism. Three allelesi.e. ε2, ε3 and ε4 were identified and five genotypes i.e. ApoE ε2/ε2, ApoE ε2/ε3, ApoE ε3/ε3, ApoE ε2/ε4, ApoE ε3/ε4 were found in three populations studied, while ApoE ε4/ε4 was absent in Surabaya, representing the westernpopulations of Indonesia. The frequency of ε2, ε3 and ε4 alleles in the western population were 0.208, 0.701and 0.092 respectively; in the middle population were 0.242, 0.618 and 0.140 respectively and in the easternpopulation of Indonesia were 0.267, 0.466 and 0.267 respectively. The highest frequency of ε2 and ε4 allelewas found in the eastern population of Indonesia. The distribution of ε2 allele were not significantly differentamong all Indonesian populations, but significantly different were found in ε3 and ε4 allele in the easternpopulation compared to those in the western and middle populations of Indonesian. It can be concluded thatthe frequency of three ApoE alleles in the western and middle populations of Indonesia was not significantlydifferent however, significantly different was observed in the frequency of ApoE ε3 and ε4 alleles from theeastern compared to those in the western and middle populations of Indonesia.


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