Pacemaker currents modulated by C-type natriuretic peptide in interstitial cells of Cajal from murine small intestine

2006 ◽  
Vol 62 (4) ◽  
pp. 281-291 ◽  
Author(s):  
Y. Zhang ◽  
L. Hua Piao ◽  
X. Huang ◽  
Y. Fei Han ◽  
P. Zhao ◽  
...  
Keyword(s):  
Small Intestine ◽  
Natriuretic Peptide ◽  
Interstitial Cells Of Cajal ◽  
Interstitial Cells ◽  
Murine Small Intestine ◽  
Cells Of Cajal ◽  
Pacemaker Currents

Induction of pacemaker currents by DA-9701, a prokinetic agent, in interstitial cells of Cajal from murine small intestine

2009 ◽  
Vol 27 (3) ◽  
pp. 307-312 ◽  
Author(s):  
Seok Choi ◽  
Jeong June Choi ◽  
Jae Yeoul Jun ◽  
Jae Woong Koh ◽  
Sang Hun Kim ◽  
...  
Keyword(s):  
Small Intestine ◽  
Interstitial Cells Of Cajal ◽  
Interstitial Cells ◽  
Prokinetic Agent ◽  
Murine Small Intestine ◽  
Cells Of Cajal ◽  
Pacemaker Currents

scholarly journals Regulation of pacemaker currents in interstitial cells of Cajal from murine small intestine by cyclic nucleotides

2000 ◽  
Vol 527 (1) ◽  
pp. 149-162 ◽  
Author(s):  
Sang Don Koh ◽  
Tae Wan Kim ◽  
Jae Yeol Jun ◽  
Nichola J. Glasgow ◽  
Sean M. Ward ◽  
...  
Keyword(s):  
Small Intestine ◽  
Cyclic Nucleotides ◽  
Interstitial Cells Of Cajal ◽  
Interstitial Cells ◽  
Murine Small Intestine ◽  
Cells Of Cajal ◽  
Pacemaker Currents

scholarly journals Molecular markers expressed in cultured and freshly isolated interstitial cells of Cajal

2000 ◽  
Vol 279 (2) ◽  
pp. C529-C539 ◽  
Author(s):  
Anne Epperson ◽  
William J. Hatton ◽  
Brid Callaghan ◽  
Philip Doherty ◽  
Rebecca L. Walker ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Small Intestine ◽  
Interstitial Cells Of Cajal ◽  
Expression Profiles ◽  
Interstitial Cells ◽  
Gastric Fundus ◽  
Soluble Form ◽  
Pacemaker Activity ◽  
Murine Small Intestine ◽  
Cells Of Cajal

Located within the tunica muscularis of the gastrointestinal (GI) tract are networks of cells known as interstitial cells of Cajal (ICC). ICC are critical for important basic functions of GI motility such as generation and propagation of slow-wave pacemaker activity and reception of regulatory inputs from the enteric nervous system. We have developed a novel procedure to identify and isolate individual ICC from freshly dispersed cell preparations of the murine small intestine and gastric fundus and to determine differential transcriptional expression We have compared the expression profiles of pacemaker ICC isolated from the murine small intestine (IC-MY) and ICC involved in neurotransmission from the gastric fundus (IC-IM). We have also compared expression profiles between ICC and smooth muscle cells (SMC) and between freshly isolated ICC and cultured ICC. Cultured ICC express smooth muscle myosin, whereas freshly dispersed ICC do not. All cell types express muscarinic receptor types M2and M3, neurokinin receptors NK1and NK3, and inhibitory receptor VIP-1, whereas only cultured ICC and SMC express VIP-2. Both cultured and freshly dispersed IC-IM and IC-MY express the soluble form of stem cell factor, whereas SMC from the gastric fundus express only the membrane-bound form.

Rikkunshito Depolarizes Pacemaker Potentials of Cultured Interstitial Cells of Cajal through Ghrelin Receptors in Murine Small Intestine

Digestion ◽  
2019 ◽  
Vol 101 (3) ◽  
pp. 227-238 ◽  
Author(s):  
Jeong Nam Kim ◽  
Joo Hyun Nam ◽  
Jong Rok Lee ◽  
Sang Chan Kim ◽  
Young Kyu Kwon ◽  
...  
Keyword(s):  
Small Intestine ◽  
Interstitial Cells Of Cajal ◽  
Interstitial Cells ◽  
Pacemaker Potentials ◽  
Ghrelin Receptors ◽  
Murine Small Intestine ◽  
Cells Of Cajal
Sign in / Sign up

Export Citation Format

Share Document