A Proved Case Of Recovery From Fatty Metamorphosis Of The Liver After Treatment With Lipocaic

1938 ◽  
Vol 5 (9) ◽  
pp. 607-613 ◽  
Author(s):  
David h. Rosenberg
1991 ◽  
Vol 19 (01) ◽  
pp. 41-50 ◽  
Author(s):  
Chun-Ching Lin ◽  
Ming-Hong Yen ◽  
Hui-Fen Chiu

The liver protective effect of Elephantopus scaber subsp. oblanceolata, E. mollis and Pseudoelephantopus spicatus on CCL 4 induced hepatotoxicity has been determined by liver enzyme functional test and pathological studies. As the result indicatep, the acute increase of serum transaminase (SGOT and SGPT level which was caused by CCL 4 administration (3.0ml/kg, s.c.) can be significantly reduced when treating with E. scaber subsp. oblanceolata( p < 0.001), E. mollis( p < 0.01), P. spicatus( p < 0.01). The hepatic fatty metamorphosis and necrosis of central lobule were obviously improved by treating with E. scaber subsp. oblanceolata and E. mollis, while treated with P. spicatus demonstrated only a moderate protective effect. All pharmacological and pathological effects of these three crude drugs were compared with Bupleurum chinense which has been reported previously as a treatment criteria.


1977 ◽  
Vol 127 (4) ◽  
pp. 400-404 ◽  
Author(s):  
Jarlath MacKenna ◽  
Marcos Pupkin ◽  
Carlyle Crenshaw ◽  
Michael McLeod ◽  
Roy T. Parker
Keyword(s):  

1989 ◽  
Vol 17 (01n02) ◽  
pp. 17-23 ◽  
Author(s):  
Hui-Fen Chiu ◽  
Chun-Ching Lin ◽  
Chui-Ching Yang ◽  
Fay Yang

Four crude drug extracts of Solanum incanum (entire plant), Ixeris chinensis (entire plant), Gardenia jasminoides (wild and cultivated, fructus) were adminstered to rats as dose of 1.0 g/kg, I.P. injection to screen the liver protective effect on CC14 induced hepatotoxicity. The acute increase of transaminase SGOT and SGPT levels that was caused by CC14 (1.0 ml/kg) S.C. injection can be significantly improved when treated with Solanum incanum( p <0.005), Ixeris chinensis( p <0.001), Gardenia jasminoides (cultivated) ( p <0.005) but only a moderate change was shown by means of wild Gardenia jasminoides( p <0.05). As our results indicated, the extraction of these drugs has been found to possess a marked hepatic protective effect. The hepatic fatty metamorphosis and necrosis of central lobule were obviously improved by S. incanum and .I. chinesis administration, while the effect of treatment with G. jasminoides (cultivated) demonstrated a moderate protective action and little histopathological change by G. jasminoides (wild). In contrast to B. chinese, which has been reported previously as a treatment criteria, the S. incanum( p <0.01) and I. chinensis( p <0.01) in the present study has indicated that a significantly different hepatic protective effect on CC14 induced hepatic injury.


1976 ◽  
Vol 31 (7) ◽  
pp. 539-540
Author(s):  
JOHN W. EISELE ◽  
EDWARD A. BARKER ◽  
EDWARD A. SMUCKLER

Radiology ◽  
1995 ◽  
Vol 195 (1) ◽  
pp. 125-130 ◽  
Author(s):  
J Martín ◽  
M Sentís ◽  
A Zidan ◽  
L Donoso ◽  
J Puig ◽  
...  

JAMA ◽  
1980 ◽  
Vol 243 (17) ◽  
pp. 1723 ◽  
Author(s):  
Brad Randall

1993 ◽  
Vol 161 (1) ◽  
pp. 44-46 ◽  
Author(s):  
J F Gruden ◽  
W R Webb
Keyword(s):  

Kanzo ◽  
1990 ◽  
Vol 31 (6) ◽  
pp. 647-652 ◽  
Author(s):  
Toru KANNO ◽  
Koshun KIM ◽  
Akihiro TAMORI ◽  
Seishu KIM ◽  
Hiroki SAKAGUCHI ◽  
...  

Author(s):  
P. M. Stockdale

Abstract A description is provided for Nannizzia fulva. Information is included on the disease caused by the organism, its transmission, geographical distribution, and hosts. HOSTS: Recorded only from man (but see NOTES). Guinea-pigs have been experimentally infected. DISEASE: Ringworm (dermatophytosis, tinea). Nannizzia fulva is present in the soil and apparently only rarely pathogenic. The scalp (tinea capitis) and glabrous skin (tinea corporis) may be infected. Skin lesions are inflammatory. The only proved case of scalp infection is that recorded by Uriburu (1909); according to Sabouraud (Les Teignes, 1910, p. 241) in this case there was a light inflammatory reaction and infected hairs were indistinguishable from those in M. audouinii infections. In experimental inoculations of guineapigs (Rdzanek, pers. comm.) N. fulva was slightly less virulent than N. gypsea and N. incurvata, the reaction varying from negative to strongly inflammatory. A few ectothrix hyphae breaking up into arthrospores were seen on some hairs, and infected hairs did not fluoresce under Wood's light. GEOGRAPHICAL DISTRIBUTION: Africa (Tanzania), Europe (Great Britain, Hungary, Yugoslavia), South America (Argentina). Probably world-wide in distribution in the soil, but there may be local limiting factors (e.g., in Great Britain it has been recorded only for Bristol, Somerset, and Wiltshire).


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