Technetium-99m-DTPA aerosol scintigraphy in amiodarone induced pulmonary toxicity in comparison with Ga-67 scintigraphy

2002 ◽  
Vol 16 (7) ◽  
pp. 477-481 ◽  
Author(s):  
Aysegul Dirlik ◽  
Ruya Erinc ◽  
Zehra Ozcan ◽  
Alev Atasever ◽  
Feza Bacakoglu ◽  
...  
Keyword(s):  
Pulmonary Toxicity ◽  
Technetium 99M ◽  
Aerosol Scintigraphy

Value of technetium-99m diethyltriamine pentaaceticacid radioaerosol inhalation lung scintigraphy for the stage of amiodarone-induced pulmonary toxicity

2004 ◽  
Vol 95 (2-3) ◽  
pp. 193-197 ◽  
Author(s):  
Gulay Durmus-Altun ◽  
Armagan Altun ◽  
Yavuz Sami Salihoglu ◽  
Semsi Altaner ◽  
Sakir Berkada ◽  
...  
Keyword(s):  
Pulmonary Toxicity ◽  
Lung Scintigraphy ◽  
Technetium 99M

Bleomycin lung toxicity detected by technetium-99m diethylene triamine penta-acetic acid aerosol scintigraphy

1993 ◽  
Vol 20 (2) ◽  
Author(s):  
�mer Ugur ◽  
Biray Caner ◽  
M. Derya Balbay ◽  
HalukA. �zen ◽  
Dogan Remzi ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Lung Toxicity ◽  
Technetium 99M ◽  
Diethylene Triamine ◽  
Aerosol Scintigraphy

An integrated screening method for evaluating the pulmonary toxicity of inhaled particulates: Role of microscopic techniques in assessing pulmonary macrophage clearance functions

1990 ◽  
Vol 48 (3) ◽  
pp. 826-827
Author(s):  
David B. Warheit ◽  
Lena Achinko ◽  
Mark A. Hartsky
Keyword(s):  
Bronchoalveolar Lavage ◽  
Pulmonary Toxicity ◽  
Screening Method ◽  
Pulmonary Response ◽  
Inhaled Particles ◽  
Cytochemical Analysis ◽  
Pulmonary Macrophages ◽  
Integrated Screening

There is a great need for the development of a rapid and reliable bioassay to evaluate the pulmonary toxicity of inhaled particles. A number of methods have been proposed, including lung clearance studies, bronchoalveolar lavage analysis, and in vitro cytotoxicity tests. These methods are often limited in scope inasmuch as they measure only one dimension of the pulmonary response to inhaled, instilled or incubated dusts. Accordingly, a comprehensive approach to lung toxicity studies has been developed.To validate the method, rats were exposed for 6 hours or 3 days to various concentrations of either aerosolized alpha quartz silica (Si) or carbonyl iron (CI) particles. Cells and fluids from groups of sham and dust-exposed animals were recovered by bronchoalveolar lavage (BAL). Alkaline phosphatase, LDH and protein values were measured in BAL fluids at several time points postexposure. Cells were counted and evaluated for viability, as well as differential and cytochemical analysis. In addition, pulmonary macrophages (PM) were cultured and studied for morphology, chemotaxis, and phagocytosis by scanning electron microscopy.

Technetium 99m compounds for visualization of body organs

JAMA ◽  
1965 ◽  
Vol 194 (2) ◽  
pp. 152-156 ◽  
Author(s):  
M. K. Loken
Keyword(s):  
Technetium 99M
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