Gastrin release and gastric secretion induced by dimethylxanthine in man

1982 ◽  
Vol 12 (2) ◽  
Author(s):  
Hans C. Dollinger ◽  
Sotos Raptis ◽  
Bärbel Grebe ◽  
Roland Müller
Keyword(s):  
Gastric Secretion ◽  
Gastrin Release

Characteristics of adrenocortical function, gastrin release and gastric secretion in duodenal ulcer etiology

1979 ◽  
Vol 9 (3) ◽  
pp. 197-202
Author(s):  
Yukio Nagamachi ◽  
Akira Taniguchi ◽  
Nobuo Ogata ◽  
Takuji Nakamura
Keyword(s):  
Duodenal Ulcer ◽  
Gastric Secretion ◽  
Adrenocortical Function ◽  
Gastrin Release

Paradoxical effects of gastrin releasing peptide on gastrin release and gastric secretion in the rat

1986 ◽  
Vol 21 (6) ◽  
pp. 573-578 ◽  
Author(s):  
Atsushi Takagi ◽  
Motoyuki Moriga ◽  
Hiroaki Narusawa ◽  
Haruto Uchino ◽  
Mitsuru Aoo
Keyword(s):  
Gastric Secretion ◽  
Gastrin Release ◽  
Gastrin Releasing Peptide ◽  
Paradoxical Effects

Inhibitory Effect of Pancreatic Secretin on Gastric Secretion

1957 ◽  
Vol 190 (3) ◽  
pp. 396-402 ◽  
Author(s):  
Herbert B. Greenlee ◽  
Enrique H. Longhi ◽  
Jose Delgadillo Guerrero ◽  
Thomas S. Nelsen ◽  
Abdul Latif El-Bedri ◽  
...  
Keyword(s):  
Gastric Secretion ◽  
Intravenous Injection ◽  
Inhibitory Effect ◽  
The Other ◽  
Gastrin Release ◽  
Depressant Effect ◽  
Insulin Hypoglycemia ◽  
Heidenhain Pouch ◽  
Marked Inhibition ◽  
Inhibition Of Gastric Secretion

In dogs prepared with both a vagus denervated Heidenhain pouch and a total pancreatic fistula, the intravenous injection of pancreatic secretin (Lilly) produced a profuse secretion of pancreatic juice and a simultaneous marked inhibition of gastric secretion. In dogs prepared with an isolated antrum pouch and a Heidenhain pouch the gastric secretion induced by the instillation of food in the antrum pouch was completely inhibited by the intravenous injection of pancreatic secretin. On the other hand, the intravenous injection of pancreatic secretin had little or no effect on the secretion of gastric juice produced by insulin hypoglycemia or by the injection of histamine. It is suggested that pancreatic secretin may represent the mechanism by means of which acid food in the duodenum inhibits gastric secretion. It is probable that this inhibition is caused by prevention of gastrin release from the antrum rather than to a depressant effect on the parietal cells.

scholarly journals Effects of Various Types of Vagotomy on Gastrin Release and Gastric Secretion in Dogs

1977 ◽  
Vol 122 (3) ◽  
pp. 209-222 ◽  
Author(s):  
TSUNEO SHIRATORI ◽  
TOSHIHIKO OKABAYASHI ◽  
MASATO NISHIGORI ◽  
RITSURO SAKURAI ◽  
YOSHIHIRO SHIMANO
Keyword(s):  
Gastric Secretion ◽  
Gastrin Release

Stimulation of gastrin release and gastric secretion by amino acids bathing pyloric gland area.

1977 ◽  
Vol 233 (3) ◽  
pp. E170
Author(s):  
S J Konturek ◽  
J Tasler ◽  
M Cieszkowski ◽  
M Dobrzańska ◽  
E Wünsch
Keyword(s):  
Amino Acids ◽  
Gastric Secretion ◽  
Pyloric Gland ◽  
Gastrin Release ◽  
Gland Area ◽  
Pyloric Gland Area ◽  
Stimulation Of

Comparison of prostacyclin and prostaglandin E2 on gastric secretion, gastrin release, and mucosal blood flow in dogs

1980 ◽  
Vol 25 (9) ◽  
pp. 673-679 ◽  
Author(s):  
Stanislaw J. Konturek ◽  
Andr� Robert ◽  
Alexander J. Hanchar ◽  
James E. Nezamis
Keyword(s):  
Blood Flow ◽  
Gastric Secretion ◽  
Prostaglandin E2 ◽  
Mucosal Blood Flow ◽  
Gastrin Release

scholarly journals Effects of drugs on gastrin release and gastric secretion evoked by stimuli in dogs with Heidenhain pouches

1975 ◽  
Vol 25 ◽  
pp. 155
Author(s):  
Hiroko Fuke ◽  
Isamu Yamaguchi ◽  
Hiroyuki Nishizaki ◽  
Fumio Honda
Keyword(s):  
Gastric Secretion ◽  
Gastrin Release

Effects of antral vagotomy in dogs on gastrin and gastric secretion with various stimuli

1990 ◽  
Vol 258 (6) ◽  
pp. G919-G925 ◽  
Author(s):  
B. I. Hirschowitz ◽  
J. Fong
Keyword(s):  
Gastric Secretion ◽  
Serum Gastrin ◽  
Vagal Stimulation ◽  
Gastric Fistula ◽  
Gastrin Release ◽  
Cholinergic Stimulation ◽  
Sham Feeding ◽  
Human Gastrin ◽  
Cholinergic Effects ◽  
Stimulation Of

In four gastric-fistula dogs, selective antral vagotomy markedly reduced the vagal stimulation of gastrin release, thereby defining both the vagal pathway for stimulation of gastrin and the anatomic source of such gastrin release. Despite loss of gastrin response, vagal excitation by 100 mg/kg 2-deoxy-D-glucose (2-DG) produced the same acid and pepsin responses after antral vagotomy as before, but there was an approximately 40% diminished fundic response to pentagastrin, histamine, and synthetic human gastrin, as well as to endogenous gastrin released by graded doses of bombesin. Bethanechol did not reverse the defect, ruling out inadvertent fundic vagal denervation, nor did raising serum gastrin by bombesin alter the response to vagal stimulation by 2-DG. Fundic response to bethanechol was increased by approximately 60%, and the output of gastrin increased at least fivefold after antral vagotomy. Gastrin responses to food were diminished and those to sham feeding were eliminated. Separation of the denervated antral pouch had no additional effect on acid secretion. Vagal stimulation of gastric secretion thus occurs almost exclusively through direct cholinergic effects on the fundus with little or no contribution from antral gastrin. Vagal denervation sensitizes the antrum to cholinergic stimulation.

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