Comparison of prostacyclin and prostaglandin E2 on gastric secretion, gastrin release, and mucosal blood flow in dogs

1980 ◽  
Vol 25 (9) ◽  
pp. 673-679 ◽  
Author(s):  
Stanislaw J. Konturek ◽  
Andr� Robert ◽  
Alexander J. Hanchar ◽  
James E. Nezamis
Keyword(s):  
Blood Flow ◽  
Gastric Secretion ◽  
Prostaglandin E2 ◽  
Mucosal Blood Flow ◽  
Gastrin Release

Effects of cimetidine upon gastric secretion and mucosal blood flow in the rat stressed by restraint

1980 ◽  
Vol 176 (3) ◽  
pp. 207-217 ◽  
Author(s):  
J. Hemmer ◽  
P. O. Schwille ◽  
W. Schellerer ◽  
W. Hofmann
Keyword(s):  
Blood Flow ◽  
Gastric Secretion ◽  
Mucosal Blood Flow

Methionine-Enkephalin Stimulates Gastric Secretion and Gastric Mucosal Blood Flow

1978 ◽  
Vol 158 (2) ◽  
pp. 156-160 ◽  
Author(s):  
S. J. Konturek ◽  
W. Pawlik ◽  
K. M. Walus ◽  
D. H. Coy ◽  
A. V. Schally
Keyword(s):  
Blood Flow ◽  
Gastric Secretion ◽  
Mucosal Blood Flow ◽  
Gastric Mucosal Blood Flow ◽  
Methionine Enkephalin

Absence of effect of 16,16-dimethyl prostaglandin E2 on reduction of gastric mucosal blood flow caused by indomethacin in rats

1989 ◽  
Vol 34 (9) ◽  
pp. 1369-1373 ◽  
Author(s):  
Tetsuo Arakawa ◽  
Hajime Nakamura ◽  
Shinji Chono ◽  
Hiroshi Satoh ◽  
Takashi Fukuda ◽  
...  
Keyword(s):  
Blood Flow ◽  
Prostaglandin E2 ◽  
Mucosal Blood Flow ◽  
Gastric Mucosal Blood Flow

Central neurotensin affects rat gastric integrity, prostaglandin E2, and blood flow

1989 ◽  
Vol 256 (1) ◽  
pp. G226-G232 ◽  
Author(s):  
L. Zhang ◽  
P. C. Colony ◽  
J. H. Washington ◽  
J. F. Seaton ◽  
G. L. Kauffman
Keyword(s):  
Blood Flow ◽  
Gastric Mucosa ◽  
Prostaglandin E2 ◽  
Cold Water ◽  
Mucosal Blood Flow ◽  
Gastric Mucosal Blood Flow ◽  
Protective Role ◽  
Mucosal Integrity ◽  
Microscopic Damage ◽  
Dose Dependent

The aim of this study is to define the effect(s) of centrally administered neurotensin (NT) on gastric mucosal integrity, prostaglandin E2 (PGE2) generation, and blood flow during stress induced by cold-water restraint (CWR) in rats. Intracerebroventricular (icv) NT reduced macroscopic and microscopic damage. The former effect was dose dependent and was totally blocked by indomethacin pretreatment. Gastric mucosal PGE2 increased 27 and 30% at 30 and 60 min, respectively, in nonrestrained rats given icv NT. PGE2 generation was reduced in control rats during CWR but was maintained in CWR rats treated with icv NT. Gastric mucosal blood flow (GMBF) was significantly reduced in control rats during CWR. Mucosal blood flow was maintained at nonrestraint levels in the presence of icv NT during CWR; however, this effect was abolished by parenteral indomethacin pretreatment. Similarly, intravenous 16,16-dimethyl-PGE2 (200 micrograms.kg-1.h-1) maintained GMBF of non-CWR levels as well as preventing the macroscopic damage normally associated with CWR. These data suggest a protective role for central NT on the gastric mucosa, mediated, at least in part, by PGE2 generation and gastric mucosal blood flow.

Basal Gastric Secretion, Mucosal Blood Flow and Associated Fasting Blood Hormones in the Rat

1982 ◽  
Vol 14 (5) ◽  
pp. 358-367 ◽  
Author(s):  
E. Hanisch ◽  
P.O. Schwille ◽  
W. Engelhardt
Keyword(s):  
Blood Flow ◽  
Gastric Secretion ◽  
Mucosal Blood Flow ◽  
Blood Hormones
Sign in / Sign up

Export Citation Format

Share Document