Cytogenetic effect of radiation products of cytosine: Parabanic and oxaluric acids

1981 ◽  
Vol 23 (1) ◽  
pp. 46-51
Author(s):  
K. Pešina ◽  
M. Sosna
Keyword(s):  
Cytogenetic Effect

ANTIBACTERIAL AND CYTOGENETIC EFFECT OF Cassia italica LEAF EXTRACT ON ALBINO MALE MICE

2010 ◽  
Vol 13 (4) ◽  
pp. 132-139
Author(s):  
Ebtehal H. Al-Naimy ◽  
◽  
Maythem M. Al-Amery ◽  
Ruqia M. Al-Azy ◽  
◽  
...  
Keyword(s):  
Leaf Extract ◽  
Male Mice ◽  
Cytogenetic Effect

Cytogenetic effect of carboplatin on human lymphocytes

1988 ◽  
Vol 21 (3) ◽  
Author(s):  
Tetsu Shinkai ◽  
Nagahiro Saijo ◽  
Kenji Eguchi ◽  
Yasutsuna Sasaki ◽  
Tomohide Tamura ◽  
...  
Keyword(s):  
Human Lymphocytes ◽  
Cytogenetic Effect

Cytogenetic effect of inhalational anesthetic gases

1996 ◽  
Vol 360 (3) ◽  
pp. 233-234
Author(s):  
Wagida A. Anwar ◽  
Sherief M.R. Zaki ◽  
Sahar S. Eldin ◽  
Samir M.H. Bedair ◽  
Fikry F. El-Bohkl
Keyword(s):  
Cytogenetic Effect ◽  
Inhalational Anesthetic ◽  
Anesthetic Gases

On Some Methodological Issues of Studying Cytogenetic Effects in Cancer Patients Treated with Neutron Therapy Using U-120 Cyclotron

2018 ◽  
Vol 63 (2) ◽  
pp. 47-54
Author(s):  
В. Лисин ◽  
V. Lisin
Keyword(s):  
Radiation Field ◽  
Chromosome Aberrations ◽  
Absorbed Dose ◽  
Neutron Radiation ◽  
The Body ◽  
Beam Intensity ◽  
Whole Body ◽  
Γ Radiation ◽  
Cytogenetic Effect ◽  
Tissue Equivalent

Purpose: To study dosimetric characteristics of neutron radiation field, to determine their role in the formation of the total cytogenetic effect in the patient’s body and to assess the cytogenetic dosimetry capabilities in improving the quality of NT. Material and methods: A therapeutic beam with the average neutron energy of ~6.3 MeV was obtained from the V-120 cyclotron. The radiation field of the beam was investigated with the help of two ionization chambers with different sensitivity to neutrons. Chamber with high and low sensitivities were made of polyethylene and graphite, respectively. To exclude the uncertainty associated with the change in beam intensity in time, a dosimeter monitor operating in the integral mode was used. Results: The dependence of the monitor factor on the irradiated area was measured. The distributions of the absorbed dose of neutrons and γ-radiation over the depth of the tissue-equivalent medium were found. The contribution of γ-radiation to the neutron dose was increased from ~10 % at the entry to the medium to ~30 % at a depth of 16 cm. Dose distributions of scattered neutron and γ-radiation in the plane of the end face of the forming device were obtained. The contribution of these radiations to the dose received by the patient’s body was estimated. This contribution was shown to be comparable with that from the therapeutic beam. The analysis of the influence of NT on the estimation of the frequency of chromosome aberrations in the blood of patients was carried out. Conclusion: The frequency of chromosome aberrations in the blood of patients was determined by the whole-body dose, including dose due to scattered radiation. When using equal focal doses, the cytogenetic effect was found to be dependent on the area of the irradiated field and the depth of the tumor in the patient’s body. The differences in the RBE of neutrons and γ-radiation as well as the instability of the therapeutic neutron beam intensity create uncertainties that do not allow for the necessary control over the doses using the cytogenetic dosimetry. Therefore, cytogenetic dosimetry should be combined with an effective instrument dosimetry method. The use of biodosimetry based on the assessment of the frequency of chromosome aberrations is promising for controlling the average whole-body dose, on which the overall radiation response of the body depends.

Cytotoxic and cytogenetic effect of nitrogen mustard on EUE cells pretreated with sodium warfarin

1980 ◽  
Vol 16 (1) ◽  
pp. 77-79 ◽  
Author(s):  
E. Dolfini ◽  
P. Ghersa ◽  
B. Barbieri ◽  
M.G. Donelli ◽  
A.M.Fuhrman Conti
Keyword(s):  
Nitrogen Mustard ◽  
Cytogenetic Effect

Cytogenetic effect of the thiocarbamate herbicides butylate, molinate and vernolate in the mouse bone marrow micronucleus test

1990 ◽  
Vol 242 (4) ◽  
pp. 279-283 ◽  
Author(s):  
A. Pintér ◽  
M. Csík ◽  
G. Török ◽  
A. Surján ◽  
Zs. Kelecsényi ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Micronucleus Test ◽  
Mouse Bone Marrow ◽  
Cytogenetic Effect ◽  
Bone Marrow Micronucleus
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