Immunohistochemical localization of the α and β subunits of S-100 protein in pleomorphic adenoma of the salivary glands

1989 ◽  
Vol 57 (1) ◽  
pp. 63-75 ◽  
Author(s):  
T. Ninomiya ◽  
R. Naito ◽  
Y. Okada ◽  
K. Kobayashi ◽  
M. Mori ◽  
...  
1987 ◽  
Vol 2 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Rosa Maria Tomasino ◽  
Rosabianca Nuara ◽  
Vincenza Morello ◽  
Ada Maria Florena ◽  
Elio Daniele

A series of 20 cases of pleomorphic adenoma and 19 cases of adenoid-cystic carcinoma of the salivary glands, and one case in the mammary location, were investigated regarding immunohistochemical reactivity for Tissue Polypeptid Antigen (TPA), Pre-Keratins, Vimentin, S-100 Protein, and their arrangement pattern of fibronectin. As a whole, the results support the hypothesis of morpho-structural and mainly, onto-histogenetic similarities between these tumours, but they also underline the need for great care in outlining their morpho-functional features, in relation to their different prognoses.


1986 ◽  
Vol 10 (10) ◽  
pp. 765-773 ◽  
Author(s):  
F MICHETTI ◽  
M RENDE ◽  
L LAURIOLA ◽  
V STOLFI ◽  
G CALOGERO ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Geovanni Dantas Cassali ◽  
Angélica Cavalheiro Bertagnolli ◽  
Enio Ferreira ◽  
Karine Araújo Damasceno ◽  
Conrado de Oliveira Gamba ◽  
...  

Mammary mixed tumours are the most frequent neoplasias in female dogs. In humans, mixed tumours are frequently found in the salivary glands and are known as pleomorphic adenomas. In addition to their histomorphologic similarities, mixed tumours and pleomorphic adenomas have the potential to become malignant and give rise to carcinomas in mixed tumours and carcinomas ex-pleomorphic adenoma, respectively. The factors associated with malignant transformation are still poorly known in the case of canine mixed tumours. However, this form of neoplasia tends to be associated with a better prognosis than other malignant histological types. This paper discusses the main features associated with female canine mammary mixed tumours.


2000 ◽  
Vol 114 (6) ◽  
pp. 477-480 ◽  
Author(s):  
Emre Üstündaĝ ◽  
Mete Iseri ◽  
O¨mer Aydin ◽  
Hülya Dal ◽  
Ahmet Almaç ◽  
...  

Malignant tumours of the salivary glands in children are extremely rare. We present here a 12-year-old girl initially diagnosed as pleomorphic adenoma on fine needle aspiration biopsy, and adenoid cystic carcinoma (ACC) after the lesion was excised and examined by histopathology. A wide resection of the lesion and bilateral supraomyohyoid neck dissection was performed. To our knowledge this is one of the youngest patients with ACC of the minor salivary glands. Due to its benign histological appearance, the biological agressiveness of ACC is usually underestimated. Although fine needle aspiration cytology (FNAC) is very valuable in diagnosis, cytological variations of pleomorphic adenoma must be considered. ACC of the tongue in a young age group should be treated with wide resection and selective neck dissection if the tumour is localized in places where the risk of metastasis is increased and if there is a clinically palpable lymph node. In such cases the clinician should not avoid radical operations even in a young patient.


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