Different effects of pretreatment with tritiated thymidine (3H-dTh) on radiation-induced sister chromatid exchanges (SCEs) and micronuclei inVicia faba root tip cells

1991 ◽  
Vol 33 (4) ◽  
pp. 291-297 ◽  
Author(s):  
P. Kuglik ◽  
Jana Slotova
Plant Science ◽  
2004 ◽  
Vol 167 (6) ◽  
pp. 1391-1399 ◽  
Author(s):  
Jian-Wei Pan ◽  
Ke Zheng ◽  
Dan Ye ◽  
Hui-Lan Yi ◽  
Zhi-Ming Jiang ◽  
...  

2005 ◽  
Vol 19 (2) ◽  
pp. 243-251 ◽  
Author(s):  
Saúl Flores-Maya ◽  
Sandra Gómez-Arroyo ◽  
María Elena Calderón-Segura ◽  
Rafael Villalobos-Pietrini ◽  
Stefan M. Waliszewski ◽  
...  

Genetika ◽  
2013 ◽  
Vol 45 (2) ◽  
pp. 393-403 ◽  
Author(s):  
Ivana Joksic ◽  
Sandra Petrovic ◽  
Andreja Leskovac ◽  
Jelena Filipovic ◽  
Marija Guc-Scekic ◽  
...  

Fanconi anemia (FA) is a rare genetically heterogeneous disease characterized by developmental abnormalities, progressive bone marrow failure, and cancer susceptibility. We examined spontaneous, diepoxybutane (DEB)- induced and radiation-induced sister chromatid exchanges (SCEs) in wholeblood lymphocyte cultures of bone marrow failure (BMF) patients including Fanconi anemia, mothers of affected individuals, and healthy controls. The baseline frequency of SCE in FA cells was similar to that observed in controls. However, in response to DEB SCE frequencies in FA patients and their mothers were significantly increased compared to both non-FA BMF families and healthy controls. In response to ionizing radiation, cells displayed increased frequency of SCE, but no differences between FA patients and non-FA BMF patients were seen. Our data confirm and expand previous findings by showing that SCE induced by DEB can be used as an adjunct diagnostic test not only for FA patients, but also for female heterozygous carriers, at least for complementation groups FANCA and FANCD2.


1977 ◽  
Vol 19 (2) ◽  
pp. 225-230 ◽  
Author(s):  
M. dos Santos Guerra ◽  
M. Irene B. De Moraes Fernandes

The mitotic chromosome behavior of the Brazilian semi-dwarf wheat cultivar IAS 54 (Triticum aestivum L. em Tell) is described. In root tip cells dicentrics, fragments, isochromosomes, a satellite tandemly duplicated, chromatid exchanges, aneuploidy, ring chromosomes and breaks in almost all chromosomes of the complement were observed. Since anaphase cells that were not pretreated showed bridges, disorderly condensation and micronuclei, the possibility that pretreatment was responsible for the abnormalities was eliminated. Other possible genetic factors and virus infection as causal agents were discussed.


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