History of blood gas analysis. VI. Oximetry

1986 ◽  
Vol 2 (4) ◽  
pp. 270-288 ◽  
Author(s):  
John W. Severinghaus ◽  
Poul B. Astrup
2018 ◽  
Vol 29 (1) ◽  
pp. 169-172
Author(s):  
Gian Luca Salvagno ◽  
Davide Demonte ◽  
Giuseppe Lippi

A 51-year old male patient was admitted to the hospital with acute dyspnea and history of chronic asthma. Venous blood was drawn into a 3.0 mL heparinized syringe and delivered to the laboratory for blood gas analysis (GEM Premier 4000, Instrumentation Laboratory), which revealed high potassium value (5.2 mmol/L; reference range on whole blood, 3.5-4.5 mmol/L). This result was unexpected, so that a second venous blood sample was immediately drawn by direct venipuncture into a 3.5 mL lithium-heparin blood tube, and delivered to the laboratory for repeating potassium testing on Cobas 8000 (Roche Diagnostics). The analysis revealed normal plasma potassium (4.6 mmol/L; reference range in plasma, 3.5-5.0 mmol/L) and haemolysis index (5; 0.05 g/L). Due to suspicion of spurious haemolysis, heparinized blood was transferred from syringe into a plastic tube and centrifuged. Potassium and haemolysis index were then measured in this heparinized plasma, confirming high haemolysis index (50; 0.5 g/L) and pseudohyperkalemia (5.5 mmol/L). Investigation of this case revealed that spurious haemolysis was attributable to syringe delivery in direct ice contact for ~15 min. This case emphasizes the importance of avoiding sample transportation in ice and the need of developing point of care analysers equipped with interference indices assessment.


1985 ◽  
Vol 1 (3) ◽  
pp. 180-192 ◽  
Author(s):  
John W. Severinghaus ◽  
Paul B. Astrup

1988 ◽  
Vol 68 (6) ◽  
pp. 977-977 ◽  
Author(s):  
THOMAS F. HORNBEIN

1987 ◽  
Vol 3 (2) ◽  
pp. 135-138 ◽  
Author(s):  
John W. Severinghaus ◽  
Yoshiyuki Honda

1986 ◽  
Vol 2 (3) ◽  
pp. 174-189 ◽  
Author(s):  
John W. Severinghaus ◽  
Poul B. Astrup

Author(s):  
G.G. Khubulava ◽  
A.B. Naumov ◽  
S.P. Marchenko ◽  
O.Yu. Chupaeva ◽  
A.A. Seliverstova ◽  
...  

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