Effect of purified phospholipases on glucose transport, insulin binding, and insulin action in isolated rat adipocytes

1982 ◽  
Vol 4 (4) ◽  
pp. 261-271 ◽  
Author(s):  
Tj. Wieringa ◽  
G. Bruin ◽  
W. P. M. Meerwijk ◽  
H. M. J. Krans
Keyword(s):  
Glucose Transport ◽  
Insulin Action ◽  
Insulin Binding ◽  
Rat Adipocytes ◽  
Isolated Rat

Effect of purified phospholipases on glucose transport, insulin binding, and insulin action in isolated rat adipocytes

1982 ◽  
Vol 14 (4) ◽  
pp. 261-271
Author(s):  
Tj. Wieringa ◽  
G. de Bruin ◽  
W. P. M. van Meerwijk ◽  
H. M. J. Krans
Keyword(s):  
Glucose Transport ◽  
Insulin Action ◽  
Insulin Binding ◽  
Rat Adipocytes ◽  
Isolated Rat

scholarly journals Tumour-promoting phorbol esters increase basal and inhibit insulin-stimulated lipogenesis in rat adipocytes without decreasing insulin binding

1985 ◽  
Vol 225 (2) ◽  
pp. 523-527 ◽  
Author(s):  
G van de Werve ◽  
J Proietto ◽  
B Jeanrenaud
Keyword(s):  
Protein Kinase C ◽  
Protein Kinase ◽  
Insulin Action ◽  
Phorbol Esters ◽  
Insulin Binding ◽  
Rat Adipocytes ◽  
Kinase C ◽  
Dose Dependent ◽  
Isolated Rat ◽  
Stimulation Of

In isolated rat adipocytes, tumour-promoting phorbol esters caused (1) dose-dependent stimulation of lipogenesis in the absence of insulin and (2) inhibition of the lipogenic effect of submaximal concentrations of insulin, but without affecting insulin binding. The possible involvement of protein kinase C in insulin action is discussed.

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