Urinary excretion of lead and δ-aminolevulinic acid in workers occupationally exposed to tetraethyl lead

1998 ◽  
Vol 63 (3) ◽  
pp. 185-194 ◽  
Author(s):  
Y. Duydu ◽  
N. Vural
Keyword(s):  
Urinary Excretion ◽  
Aminolevulinic Acid ◽  
Tetraethyl Lead ◽  
Occupationally Exposed

Study on Kidney Function in Female Workers Exposed to Perchlorethylene

1990 ◽  
Vol 9 (6) ◽  
pp. 377-380 ◽  
Author(s):  
A. Vyskočil ◽  
S. Emminger ◽  
J. Tejral ◽  
Z. Fiala ◽  
E. Ettlerova ◽  
...  
Keyword(s):  
Urinary Excretion ◽  
Biochemical Parameters ◽  
Renal Damage ◽  
Ambient Air ◽  
Exposed Group ◽  
Control Group ◽  
Total Proteins ◽  
Dry Cleaning ◽  
Female Workers ◽  
Occupationally Exposed

1 Biochemical markers of kidney damage were examined in 16 female workers chronically exposed to tetrachlorethylene (TCE) in five dry-cleaning shops. The results were compared with those obtained in 13 females non-occupationally exposed to organic solvents. 2 The intensity of exposure was monitored by personal environmental monitoring. The time-weighed average exposure to TCE amounted to 157 mg m-3 (range 9-799 mg m-3). A satisfactory agreement was found between the concentration of TCE in ambient air sampled with the charcoal tube method and with a passive dosimeter. 3 The urinary excretion of lysozyme was increased in the exposed group. No difference was found in the urinary excretion of albumin, β2-microglobulin, lactate dehydrogenase, total proteins or glucose. The prevalence of abnormal values of biochemical parameters in the exposed group did not differ from that observed in the control group. No correlation was found between the level of TCE exposure and biochemical parameters. 4 The present study suggests that chronic exposure to TCE does not lead to renal damage.

Evaluation of pteridine metabolism in battery workers chronically exposed to lead

2006 ◽  
Vol 25 (7) ◽  
pp. 353-359 ◽  
Author(s):  
A B Engin ◽  
D Tuzun ◽  
G Sahin
Keyword(s):  
Neurological Disorders ◽  
High Performance ◽  
Aminolevulinic Acid ◽  
Control Group ◽  
Occupationally Exposed ◽  
Lead Levels ◽  
Urinary Lead ◽  
Urinary Neopterin ◽  
Battery Workers ◽  
Increased Activity

Occupationally-exposed lead affects the neuromuscular junction and might cause disturbances in the locomotor activity. This study was undertaken to evaluate pteridine metabolism, in which neurotransmitters are synthesized in battery workers. Urinary neopterin, biopterin and creatinine were measured using high performance liquid chromatography. Serum neopterin concentrations were detected by enzyme-linked immunoassay. Blood dihydropteridine reductase (DHPR) activities and delta-aminolevulinic acid (delta-ALA) were measured spectrophotometrically. Blood and urinary lead were detected by atomic absorption spectroscopy. Significantly increased blood and urinary lead levels, urinary neopterin, biopterin and delta-ALA were found in workers, while DHPR activities were indifferent compared to control group. Urinary creatinine decreased. This is the first study to demonstrate that increased activity of the pteridine pathway results in the accumulation of the neurotransmitters that may be responsible for the neurological disorders.

scholarly journals Urinary excretion of phenol, catechol, hydroquinone, and muconic acid by workers occupationally exposed to benzene

1998 ◽  
Vol 55 (10) ◽  
pp. 705-711 ◽  
Author(s):  
N. Rothman ◽  
W. E. Bechtold ◽  
S. N. Yin ◽  
M. Dosemeci ◽  
G. L. Li ◽  
...  
Keyword(s):  
Urinary Excretion ◽  
Muconic Acid ◽  
Occupationally Exposed

Elemental plasma content and urinary excretion in vineyard farmers occupationally exposed to pesticides in southern Brazil

2021 ◽  
Author(s):  
Renata Sano Lini ◽  
Raul Gomes Aguera ◽  
Danielle Hoeltgebaum ◽  
Fernanda Pollo Paniz ◽  
Tatiana Pedron ◽  
...  
Keyword(s):  
Urinary Excretion ◽  
Southern Brazil ◽  
Occupationally Exposed

scholarly journals Estimation of Urinary Delta Aminolevulinic Acid Levels in Females of Reproductive Age as an Index of Lead Exposure

2021 ◽  
Vol 14 (02) ◽  
pp. 823-827
Author(s):  
Sachin A. Patharkar ◽  
Uzma M J Shaikh ◽  
Neelam J. Patil ◽  
Alka V. Nerurkar ◽  
Umesh- Shinde
Keyword(s):  
Lead Exposure ◽  
Aminolevulinic Acid ◽  
Daily Basis ◽  
Cross Sectional Study ◽  
Reproductive Age ◽  
Reference Level ◽  
Toxic Heavy Metal ◽  
Cross Sectional ◽  
Occupationally Exposed ◽  
High Level

Lead is a toxic heavy metal whose widespread use has caused extensive environmental contamination and health problems particularly in children and women of reproductive age. It affects multiple body systems, including the neurologic, hematologic, gastrointestinal, cardiovascular, and renal systems. Recent studies have shown that lead, has the potential to harm not only the young and the occupationally-exposed, but also older people and females with in the reproductive age. They may have been exposed to lead while working in unregulated occupations, or they may have encountered more lead in the environment on a daily basis. The Aim of the present study is to estimate urinary δ-ALA levels in heterogenous population of females in the reproductive age as an index of lead exposure. This cross- sectional study was conducted on randomly chosen 80 females of reproductive age from different areas of Mumbai with brief history related lead exposure. The morning first mid stream urine samples were collected with all standard precautions and analyzed for δ-ALA using modified Ehrlich’s reagent method. Out of the 80 samples – 69 samples (86.25%) urinary δ-ALA had levels above reference level i.e. (< 5mg/l). This is alarming. The reasons for this exposure may vary and we could not find a single cause for such a high level exposure, but we can say that it is closely related to the duration of exposure. Hence it is to conclude that it is difficult to stop lead exposure completely but by taking necessary precautions and providing health education we can reduce the lead exposure and its ill effects on health.

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