Distribution of immunoglobulin-producing cells in the human gastrointestinal tract —Cellular localization of adenovirus antibody—

1970 ◽  
Vol 5 (1) ◽  
pp. 92-92
Author(s):  
T. Tobe ◽  
C. Hamada
Keyword(s):  
Gastrointestinal Tract ◽  
Cellular Localization ◽  
Human Gastrointestinal Tract

scholarly journals Identification and localization of soluble sulfotransferases in the human gastrointestinal tract

2007 ◽  
Vol 404 (2) ◽  
pp. 207-215 ◽  
Author(s):  
Wera Teubner ◽  
Walter Meinl ◽  
Simone Florian ◽  
Michael Kretzschmar ◽  
Hansruedi Glatt
Keyword(s):  
Gastrointestinal Tract ◽  
Gut Microbiota ◽  
Cellular Localization ◽  
Reactive Metabolites ◽  
Human Gastrointestinal Tract ◽  
Food Borne ◽  
Messenger Molecules ◽  
Colon And Rectum ◽  
Low Levels ◽  
Presystemic Elimination

Soluble SULTs (sulfotransferases) are important in the regulation of messenger molecules and the elimination of xenobiotics. However, sulfo-conjugation of various substrates can also lead to the formation of reactive metabolites that may induce cancer and cause other damage. The aim of the present study was to identify the SULT forms expressed in the human gastrointestinal tract, especially the colon and rectum (common sites for cancer), and to determine their cellular localization. Normal colonic or rectal tissue, resected with tumours, was obtained from 39 subjects. For comparison, we additionally studied one to four samples from stomach, jejunum, ileum, cecum and liver. SULTs were detected by immunoblotting, immunohistochemistry and measurement of enzyme activities. SULT1A1, 1A3 and 1B1 were found in all parts of the gastrointestinal tract, often exceeding levels in liver (where these forms were present at high, undetectable and low levels respectively). They were predominantly localized in differentiated enterocytes. SULT1E1 and 2A1 were only detected in liver, jejunum, ileum and cecum. SULT1C1 was readily found in stomach, but was negligible elsewhere. SULT1A2 was present at low levels in individual samples. The remaining forms were not detected with the limitation that only high levels could be recognized with the antisera used. In conclusion, SULTs are abundant in the gastrointestinal tract of man. We suspect that they are involved in the presystemic elimination of bioactive food-borne components, including aglycones released by gut microbiota, as well as the bioactivation of some procarcinogens.

The Design of a Hydraulic Suction Tube for Peroral Biopsy of the Human Gastrointestinal Tract

1962 ◽  
Vol 42 (3) ◽  
pp. 281-284 ◽  
Author(s):  
Wayne E. Quinton ◽  
Arnold L. Flick ◽  
Cyrus E. Rubin
Keyword(s):  
Gastrointestinal Tract ◽  
Human Gastrointestinal Tract ◽  
Suction Tube

The Host Genotype Affects the Bacterial Community in the Human Gastrointestinal Tract

2001 ◽  
Vol 13 (3) ◽  
Author(s):  
Erwin G. Zoetendal ◽  
Antoon D. L. Akkermans ◽  
Wilma M. Akkermans-van Vliet ◽  
J. Arjan G. M. De Visser ◽  
Willem M. De Vos
Keyword(s):  
Gastrointestinal Tract ◽  
Bacterial Community ◽  
Human Gastrointestinal Tract ◽  
Host Genotype

Food-grade titanium dioxide particles decrease the bioaccessibility of iron released from spinach leaves in simulated human gastrointestinal tract

2021 ◽  
Author(s):  
Chunyang Li ◽  
Chuanxin Ma ◽  
Heping Shang ◽  
Jason C. White ◽  
David Julian McClements ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Gastrointestinal Tract ◽  
Amylase Activity ◽  
Human Gastrointestinal Tract ◽  
Food Grade ◽  
Spinach Leaves

E171 reduced Fe bioaccessibility of spinach in a simulated gastrointestinal tract via two mechanisms: the inhibition of α-amylase activity and adsorption of released Fe from spinach.

scholarly journals Cellular localization of mRNAs for the prostaglandin E receptor subtypes in the mouse gastrointestinal tract

1997 ◽  
Vol 73 ◽  
pp. 195
Author(s):  
Yukihiko Sugimoto ◽  
Kimiko Morimoto ◽  
Masato Kiusuyama ◽  
Kazuhito Tsuboi ◽  
Kiyohiko Kishi ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Cellular Localization ◽  
Prostaglandin E ◽  
Receptor Subtypes

Dissolution Media Simulating Conditions in the Proximal Human Gastrointestinal Tract: An Update

2008 ◽  
Vol 25 (7) ◽  
pp. 1663-1676 ◽  
Author(s):  
Ekarat Jantratid ◽  
Niels Janssen ◽  
Christos Reppas ◽  
Jennifer B. Dressman
Keyword(s):  
Gastrointestinal Tract ◽  
Human Gastrointestinal Tract
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