Regression of attained milestones in an HIV infected Infant

2001 ◽  
Vol 68 (10) ◽  
pp. 991-994
Author(s):  
Purnima Madhivanan ◽  
S. N. Mothi ◽  
N. Kumarasamy ◽  
Tokugha Yepthomi ◽  
John Lambert ◽  
...  
Keyword(s):  
Infected Infant

scholarly journals Use of Coreceptors Other Than CCR5 by Non-Syncytium-Inducing Adult and Pediatric Isolates of Human Immunodeficiency Virus Type 1 Is Rare In Vitro

1998 ◽  
Vol 72 (11) ◽  
pp. 9337-9344 ◽  
Author(s):  
Yi-jun Zhang ◽  
Tatjana Dragic ◽  
Yunzhen Cao ◽  
Leondios Kostrikis ◽  
Douglas S. Kwon ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Human Immunodeficiency Virus Type ◽  
Virus Type ◽  
Viral Entry ◽  
Infected Infant ◽  
Subtype B ◽  
Immunodeficiency Virus ◽  
Hiv 1

ABSTRACT We have tested a panel of pediatric and adult human immunodeficiency virus type 1 (HIV-1) primary isolates for the ability to employ the following proteins as coreceptors during viral entry: CCR1, CCR2b, CCR3, CCR4, CCR5, CCR8, CXCR4, Bonzo, BOB, GPR1, V28, US28, and APJ. Most non-syncytium-inducing isolates could utilize only CCR5. All syncytium-inducing viruses used CXCR4, some also employed V28, and one (DH123) used CCR8 and APJ as well. A longitudinal series of HIV-1 subtype B isolates from an infected infant and its mother utilized Bonzo efficiently, as well as CCR5. The maternal isolates, which were syncytium inducing, also used CXCR4, CCR8, V28, and APJ.

Epstein-Barr Virus (EBV)-Antibody Profile in an Infant Congenitally Infected by the EBV

PEDIATRICS ◽  
1982 ◽  
Vol 70 (5) ◽  
pp. 823-824
Author(s):  
R. Shihman Chang
Keyword(s):  
Epstein Barr Virus ◽  
In Utero ◽  
Healthy Infant ◽  
Infected Infant ◽  
Initial Dilution ◽  
Barr Virus ◽  
Antibody Profile ◽  
Epstein Barr ◽  
Apparently Healthy

In 1973, Blankenship and I reported on an apparently healthy infant who was infected by the Epstein-Barr virus (EBV) in utero.1 In testing for EBV capsid (VCA) antibody in this infant, we found weak positive reactions with undiluted sera but negative reactions with sera diluted at 1/4. Because sera were generally tested at the initial dilution of 1/8 or 1/10 and were considered as negative for VCA antibody if there were no visible reactions,2,3 we concluded that the congenitally infected infant was EBV-seronegative. See table in the PDF file

AIDS-Associated Lymphoma of the Brain in a Child

PEDIATRICS ◽  
1988 ◽  
Vol 82 (4) ◽  
pp. 678-679
Author(s):  
SHARON B. MURPHY
Keyword(s):  
Brain Biopsy ◽  
Primary Lymphoma ◽  
Brain Lymphoma ◽  
Infected Infant ◽  
Pediatric Aids ◽  
Neurologic Deterioration ◽  
True Frequency ◽  
The Brain

Invited Comment.— The HIV-infected infant with a primary lymphoma of the brain reported by Professor Cocchi and colleagues from Italy adds another case to the series of pediatric AIDS-associated brain lymphomas already reported by others.1-3 The true frequency of these opportunistic cancers is unknown, but, surely, we are just beginning to see the tip of the iceberg. Neurologic deterioration is common in pediatric AIDS,2 and, unless cases suspicious for brain lymphoma are aggressively investigated by neuroradiologic examinations and brain biopsy, they are unlikely to be diagnosed antemortem.

Death of a 3 Month-Old Infected Infant with Dilated Cardiomyopathy after COVID-19 Infection: A Case Report

2021 ◽  
Author(s):  
Fatemeh Baghalsafa ◽  
Hossein Neamatzadeh ◽  
Sedigheh Ekraminasab
Keyword(s):  
Case Report ◽  
Dilated Cardiomyopathy ◽  
Cardiac Injury ◽  
Viral Myocarditis ◽  
Rare Condition ◽  
Underlying Disease ◽  
Pediatric Emergency ◽  
Sufficient Evidence ◽  
Infected Infant ◽  
Severe Underlying Disease

Background: Several numbers of studies have reported that coronavirus disease-2019 (COVID-19) in infants and children have shown milder symptoms and a better prognosis than in adult patients. However, there is no sufficient evidence on the effect of cardiovascular involvement in COVID-19 in the infant. Case Report: Here, we report an infant infected with COVID-19 with the manifestations of dilated myocarditis. The patient was referred to Pediatric Emergency with lethargy and tachypnea. On physical examination, she had holosystolic murmur with grade 3/6. The laboratory examinations showed anemia as well as increased alkaline phosphatase (ALP) levels. Due to respiratory distress, she was intubated and put under mechanical ventilation. The diagnosis of COVID-19 infection was confirmed by real-time polymerase chain reaction (RT-PCR) using a pharyngeal specimen. Finally, dilated cardiomyopathy (DCM) was diagnosed and one day after hospitalization the infant was died due to complications of DCM. Conclusion: It seems that in the infant with severe underlying disease, even a mild COVID-19 infection, may be lethal. Focal viral myocarditis is a very rare condition described by localized disturbance of the myocardium occurring in ventricular dysfunction with significant morbidity and mortality. Thus, due to the possibility of cardiac injury in infected neonates with COVID-19 disease and the manifestation of myocarditis, effective measurement is recommended.

scholarly journals TB Presenting as Recurrent Pneumonia in a HIV-Infected Infant in Central Viet Nam

Reports ◽  
2018 ◽  
Vol 1 (2) ◽  
pp. 12
Author(s):  
Phuong Nguyen ◽  
Son Nguyen ◽  
Thinh Nguyen ◽  
Ben Marais
Keyword(s):  
Antiretroviral Treatment ◽  
Social Stigma ◽  
Correct Diagnosis ◽  
Severe Pneumonia ◽  
Careful Consideration ◽  
First Line ◽  
Recurrent Pneumonia ◽  
Infected Infant ◽  
Immunodeficiency Virus ◽  
Hiv Exposure

We report on a six-month-old infant admitted to our intensive care unit (ICU) with recurrent severe pneumonia. The mother was infected with human immunodeficiency virus (HIV)-infected, but initially failed to disclose this to doctors. Neither did she report the grandmother of the child’s chronic coughing, likely due to tuberculosis (TB). The infant was diagnosed with X-pert MTB/RIF® confirmed TB and tested positive for HIV infection. Once a correct diagnosis was established, the child demonstrated good recovery with appropriate TB and antiretroviral treatment (ART). The case demonstrates the importance of including TB in the differential diagnosis for young children not responding to first-line pneumonia treatment, especially in TB endemic areas. Taking a meticulous TB and HIV exposure history, with careful consideration of potential social stigma, is essential. It also demonstrates how the inaccessibility of HIV results and the absence of a continuous patient record may jeopardize patient care.

scholarly journals Cytokines in the Nasal Washes of Children with Respiratory Syncytial Virus Bronchiolitis

2006 ◽  
Vol 19 (1) ◽  
pp. 205873920601900 ◽  
Author(s):  
F. Midulla ◽  
V. Tromba ◽  
L. LO Russo ◽  
F. Mileto ◽  
G. Sabatino ◽  
...  
Keyword(s):  
Immune Response ◽  
Respiratory Syncytial Virus ◽  
Virus Infection ◽  
Lung Inflammation ◽  
Virus Infections ◽  
Nasal Wash ◽  
Respiratory Illnesses ◽  
Infected Infant ◽  
Cell Mediated Immune Response ◽  
Syncytial Virus

Although respiratory syncytial (RS) virus is the major cause of bronchiolitis and pneumonia in young children, the factors that regulate the associated lung inflammation have not been defined. The levels of interleukin (IL)10, IL-12, and interferon (IFN) were determined in the nasal wash samples from 20 infants with a clinical diagnosis of bronchiolitis, seven with confirmed RS virus infections and 9 control children without respiratory illnesses. IL-10 levels were significantly higher in acute nasal wash samples (1–4 d post-hospitalization) from RS virus- infected infants than in convalescent samples from these children (14–21 d post-hospitalization), from children with other forms of bronchiolitis and from control children. In contrast, only one RS virus-infected infant had detectable IL-12 in an acute nasal wash sample. IFN activity was not detected in any samples from RS virus-infected children. RS virus infection stimulates IL-10 expression but not IL-12 and IFN, possibly contributing to an ineffective cell-mediated immune response.

Use of natural surfactant in an HIV-infected infant withPneumocystis carinii pneumonia

1996 ◽  
Vol 22 (6) ◽  
pp. 611-612 ◽  
Author(s):  
S. C. Marriage ◽  
H. Underhill ◽  
S. Nadel
Keyword(s):  
Infected Infant ◽  
Natural Surfactant

Successful Treatment with Oral Valganciclovir of Primary CMV Enterocolitis in a Congenitally Infected Infant

2011 ◽  
Vol 30 (6) ◽  
pp. 437-441 ◽  
Author(s):  
Karina Irizarry ◽  
Stefany Honigbaum ◽  
Gail Demmler-Harrison ◽  
Sara Rippel ◽  
Michael Wilsey
Keyword(s):  
Successful Treatment ◽  
Infected Infant ◽  
Oral Valganciclovir

Fulminant human herpesvirus six encephalitis in a human immunodeficiency virus-infected infant

1995 ◽  
Vol 45 (3) ◽  
pp. 288-292 ◽  
Author(s):  
Konstance K. Knox ◽  
Daniel P. Harrington ◽  
Donald R. Carrigan
Keyword(s):  
Human Immunodeficiency Virus ◽  
Human Herpesvirus ◽  
Infected Infant ◽  
Immunodeficiency Virus
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