Effect of semax on homeostasis of gastric mucosa in albino rats

2000 ◽  
Vol 130 (3) ◽  
pp. 871-873 ◽  
Author(s):  
S. E. Zhuikova ◽  
E. A. Smirnova ◽  
Z. V. Bakaeva ◽  
G. E. Samonina ◽  
I. P. Ashmarin
Keyword(s):  
Gastric Mucosa ◽  
Albino Rats

Mechanisms for the effect of arginine-containing dermorphin analogue on proliferative processes in the gastric mucosa of albino rats

2007 ◽  
Vol 144 (3) ◽  
pp. 309-311 ◽  
Author(s):  
M. U. Fleishman ◽  
E. U. Zhivotova ◽  
O. A. Lebedko ◽  
V. I. Deigin ◽  
S. S. Timoshin
Keyword(s):  
Gastric Mucosa ◽  
Albino Rats

scholarly journals Anti-inflammatory activity of acacia catechu-bark aqueous solution in aspirin induced gastric ulcer in rodents

2021 ◽  
Vol 8 (12) ◽  
pp. 5649
Author(s):  
Uzma Waseem ◽  
Syeda Rizwana Jafri ◽  
Sarah Khalid ◽  
Fauzia Qureshi ◽  
Nadia Majeed ◽  
...  
Keyword(s):  
Gastric Mucosa ◽  
Inflammatory Cells ◽  
Protective Role ◽  
Gastric Injury ◽  
Medical Institute ◽  
Control Group ◽  
Albino Rats ◽  
Anti Inflammatory ◽  
Group B ◽  
Acacia Catechu

Background: Aspirin is amongst the most widely used drugs and has many adverse effects on gastric mucosa. Anti-inflammatory properties of Acacia catechu have been established already. Objective was to evaluate the histopathological changes induced by aspirin in the stomach of albino rats and to assess the protective effect of different doses of Acacia catechu.Methods: Experimental study Postgraduate Medical Institute, Lahore for 21 days. Forty-eight adult albino rats, both males and female, were divided into four groups A, B, C and D randomly; each comprising of 12 rats. Group A was control, group B was given aspirin 100 mg/kg and group C and D were given aspirin 100 mg/kg along with Acacia catechu 250 mg/kg and 500 mg/kg respectively by oral route. The rats from individual group were sacrificed on 3rd day, 7th day and 14th day and stomachs were examined under light microscope to observe the inflammatory cells infiltration.Results: Gross and microscopic findings on days 3, 7 and 14 were similar. Control groups A1, A2 and A3 showed normal healthy gastric mucosa and the least number of inflammatory cells. In group B, aspirin produced ulcerations and linear breaks; with highest inflammatory infiltrates. On microscopic examination, numerous inflammatory cells were noted. Group C and D rats had minimum ulcer index and fewer inflammatory cells.Conclusions: Acacia catechu has protective role against gastric injury by inhibiting inflammation. 

The Effect of Cold Stress on the Gastric Mucosa of Adult Male Albino Rats: A Light Microscope Study

2012 ◽  
Vol 19 (1) ◽  
Author(s):  
Ghada Abdel-Hamid ◽  
Rana El-Beshbishy ◽  
Afrah Al-Awa
Keyword(s):  
Gastric Mucosa ◽  
Cold Stress ◽  
Adult Male ◽  
Microscope Study ◽  
Light Microscope ◽  
Albino Rats

scholarly journals Тhe Impact Of Positive Acceleration (+Gz) on Antioxidant Capacity and Histopathological Alterations in Different Organs and Tissues in Rats

2017 ◽  
Vol 18 (3) ◽  
pp. 203-212
Author(s):  
Jelena Ristic ◽  
Tamara Nikolic ◽  
Jovana Jeremic ◽  
Isidora Stojic ◽  
Snezana Janicijevic-Hudomal ◽  
...  
Keyword(s):  
Gastric Mucosa ◽  
Antioxidant Capacity ◽  
Total Content ◽  
Control Group ◽  
Albino Rats ◽  
Histopathological Alterations ◽  
Antioxidant Enzyme System ◽  
Biochemical Systems ◽  
Wistar Albino Rats ◽  
The Impact

Abstract Since the early 1940s, a significant amount of research has been conducted to describe the impact of the high-G acceleration on the cardiovascular system. The objective of the present study was to examine the role of the antioxidant enzyme system under biodynamic stress in the liver, heart and gastric mucosa in response to high-magnitude +Gz exposure in a rat model. Twenty adult male Wistar albino rats (10 rats per group; 9-11 weeks old, 200-250 g b.w.) were divided into the following two groups: control and G (exposed to a biodynamic stress model under positive (+7 Gz) acceleration for 40 s). The influence of acute biodynamic stress on pro-oxidative parameters in the rat liver (xanthine oxidase (XOD), catalase (CAT), peroxidase (Px), glutathione peroxidase (GSH-Px), total content of glutathione (GSH), lipid peroxidation (LPx)) and on histopathological alterations in the liver, cardiac muscle and gastric mucosa was examined. Biodynamic stress resulting from positive (+7 Gz) acceleration resulted in a highly statistically signifi cant increase of CAT GSH-Px activity compared to the control group. The LPx levels were significantly decreased, but the GSH contents and the activities of other enzymes were not significantly changed. Significant microscopic changes in the liver, heart and gastric mucosa were observed in the G group. These results clearly indicate that +Gz acceleration alters biochemical systems. These alterations in cellular processes may be mediated by influences of hypoxia or ischaemia via changes in the antioxidant capacity.

scholarly journals Possible Effect of Mosapride on Gastric Mucosa and Indomethacin Induced Gastric Ulcer in Male Albino Rats

2014 ◽  
Vol 4 (1-2) ◽  
Author(s):  
Sohair S. El menshawy ◽  
Gehane A. El-Gindy ◽  
Ahmed A. Abd El-Sameea ◽  
Amira M. Abd Elhamid ◽  
Amira A. ◽  
...  
Keyword(s):  
Gastric Ulcer ◽  
Gastric Mucosa ◽  
Albino Rats

scholarly journals Histological Study of the Caffeine Effect on Intact Gastric Mucosa and Induced Gastric Ulcer in Adult Male Albino Rats

2020 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Asmaa Abd_Elhamid ◽  
Mona Salem ◽  
Shadia Mahmoud ◽  
mona mohamed Abd Elgalil
Keyword(s):  
Gastric Ulcer ◽  
Gastric Mucosa ◽  
Adult Male ◽  
Histological Study ◽  
Albino Rats

scholarly journals INCIDENCE OF GASTRIC ULCER IN ALBINO RATS FED DIETS DEFICIENT IN VITAMIN B (B1)

1932 ◽  
Vol 56 (3) ◽  
pp. 391-398 ◽  
Author(s):  
Gilbert Dalldorf ◽  
Minerva Kellogg
Keyword(s):  
Peptic Ulcer ◽  
Gastric Ulcer ◽  
Gastric Mucosa ◽  
Control Group ◽  
Albino Rats ◽  
Vitamin B ◽  
Gastric Lesions ◽  
Lesser Curvature

73 per cent of a group of albino rats whose diet was deficient in vitamin B have been found to have ulcerations of the gastric mucosa. A control group was found to be free from gastric lesions. Of 74 observed lesions eight were chronic, indurated ulcers resembling chronic peptic ulcer in man. The chronicity of the ulcers seems to be related to the duration rather than the degree of the deficiency. The lesions were generally located along the lesser curvature of the stomach, as is true in man. The size of the lesions in rat and man are comparable if adjustment is made for differences in the sizes of the organs.

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