scholarly journals Possible Effect of Mosapride on Gastric Mucosa and Indomethacin Induced Gastric Ulcer in Male Albino Rats

2014 ◽  
Vol 4 (1-2) ◽  
Author(s):  
Sohair S. El menshawy ◽  
Gehane A. El-Gindy ◽  
Ahmed A. Abd El-Sameea ◽  
Amira M. Abd Elhamid ◽  
Amira A. ◽  
...  
Keyword(s):  
Gastric Ulcer ◽  
Gastric Mucosa ◽  
Albino Rats

scholarly journals Histological Study of the Caffeine Effect on Intact Gastric Mucosa and Induced Gastric Ulcer in Adult Male Albino Rats

2020 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Asmaa Abd_Elhamid ◽  
Mona Salem ◽  
Shadia Mahmoud ◽  
mona mohamed Abd Elgalil
Keyword(s):  
Gastric Ulcer ◽  
Gastric Mucosa ◽  
Adult Male ◽  
Histological Study ◽  
Albino Rats

scholarly journals INCIDENCE OF GASTRIC ULCER IN ALBINO RATS FED DIETS DEFICIENT IN VITAMIN B (B1)

1932 ◽  
Vol 56 (3) ◽  
pp. 391-398 ◽  
Author(s):  
Gilbert Dalldorf ◽  
Minerva Kellogg
Keyword(s):  
Peptic Ulcer ◽  
Gastric Ulcer ◽  
Gastric Mucosa ◽  
Control Group ◽  
Albino Rats ◽  
Vitamin B ◽  
Gastric Lesions ◽  
Lesser Curvature

73 per cent of a group of albino rats whose diet was deficient in vitamin B have been found to have ulcerations of the gastric mucosa. A control group was found to be free from gastric lesions. Of 74 observed lesions eight were chronic, indurated ulcers resembling chronic peptic ulcer in man. The chronicity of the ulcers seems to be related to the duration rather than the degree of the deficiency. The lesions were generally located along the lesser curvature of the stomach, as is true in man. The size of the lesions in rat and man are comparable if adjustment is made for differences in the sizes of the organs.

scholarly journals Prevention of peptic ulcer by aqueous extract of Aegle marmelos leaf in rats

2018 ◽  
Vol 12 (1) ◽  
pp. 11-14
Author(s):  
Sharmin Rahman ◽  
Mohammad Rezaul Quader ◽  
Md Ismail Khan
Keyword(s):  
Body Weight ◽  
Peptic Ulcer ◽  
Gastric Ulcer ◽  
Aqueous Extract ◽  
Protective Efficacy ◽  
Albino Rats ◽  
Ulcer Formation ◽  
Aegle Marmelos ◽  
Rat Stomach ◽  
Dose Dependent

Background and objectives: Aegle marmelos (Bael), a medicinal plant, has been widely used indigenously to treat many diseases in Bangladesh and other countries. The present study was carried out to evaluate the efficacy of A. marmelos leaf to prevent ethanol induced gastric ulcer in a rat model.Methods: Thirty two Wister albino rats of either sex, weighing between 100-150g, were fed 200 mg/kg or 400 mg/kg aqueous extract of A. marmelos leaves one hour prior to oral administration of 90% ethanol (1 ml/200 gm body weight) to induce gastric ulcer. The animals were sacrificed after one hour and ulcer scores and index were determined. The protective efficacy of A. marmelos aqueous extract was expressed as percentage protection of ulcer.Results: Aqueous extract exhibited significant (p<0.05) dose dependent protection against gastric ulcer formation by ethanol in rat stomach. Percentage protection of ulcer with 200 mg/kg and 400 mg/kg of aqueous extract of A. marmelos leave were 19.3% and 37.2% respectively compared to standard anti-peptic ulcer drug omeprazole (50.4%).Conclusion: Thus, crude extracts of A. marmelos leave have been shown to have potential ability to prevent experimentally induced peptic ulcer formation in animal model.IMC J Med Sci 2018; 12(1): 11-14

Mechanisms for the effect of arginine-containing dermorphin analogue on proliferative processes in the gastric mucosa of albino rats

2007 ◽  
Vol 144 (3) ◽  
pp. 309-311 ◽  
Author(s):  
M. U. Fleishman ◽  
E. U. Zhivotova ◽  
O. A. Lebedko ◽  
V. I. Deigin ◽  
S. S. Timoshin
Keyword(s):  
Gastric Mucosa ◽  
Albino Rats

Immunohistochemical study of dopamine in rat gastric mucosa with acute gastric ulcer

1994 ◽  
Vol 29 (6) ◽  
pp. 695-702 ◽  
Author(s):  
Naoto Kawakita ◽  
Yoshi Nagahata ◽  
Yoichi Saitoh
Keyword(s):  
Gastric Ulcer ◽  
Gastric Mucosa ◽  
Immunohistochemical Study ◽  
Rat Gastric Mucosa

A comparative study on the possible protective effect of esomeprazole, spirulina, wheatgrass on indomethacin-induced gastric ulcer in male albino rats

2019 ◽  
Vol 46 (5) ◽  
pp. 4843-4860 ◽  
Author(s):  
Amy Fakhry Boushra ◽  
Asmaa Mohammed Elsayed ◽  
Noha Abdellatif Ibrahim ◽  
Maha Khaled Abdelwahed ◽  
Eman Ibrahim Ahmed
Keyword(s):  
Gastric Ulcer ◽  
Comparative Study ◽  
Protective Effect ◽  
Albino Rats

scholarly journals Anti-inflammatory activity of acacia catechu-bark aqueous solution in aspirin induced gastric ulcer in rodents

2021 ◽  
Vol 8 (12) ◽  
pp. 5649
Author(s):  
Uzma Waseem ◽  
Syeda Rizwana Jafri ◽  
Sarah Khalid ◽  
Fauzia Qureshi ◽  
Nadia Majeed ◽  
...  
Keyword(s):  
Gastric Mucosa ◽  
Inflammatory Cells ◽  
Protective Role ◽  
Gastric Injury ◽  
Medical Institute ◽  
Control Group ◽  
Albino Rats ◽  
Anti Inflammatory ◽  
Group B ◽  
Acacia Catechu

Background: Aspirin is amongst the most widely used drugs and has many adverse effects on gastric mucosa. Anti-inflammatory properties of Acacia catechu have been established already. Objective was to evaluate the histopathological changes induced by aspirin in the stomach of albino rats and to assess the protective effect of different doses of Acacia catechu.Methods: Experimental study Postgraduate Medical Institute, Lahore for 21 days. Forty-eight adult albino rats, both males and female, were divided into four groups A, B, C and D randomly; each comprising of 12 rats. Group A was control, group B was given aspirin 100 mg/kg and group C and D were given aspirin 100 mg/kg along with Acacia catechu 250 mg/kg and 500 mg/kg respectively by oral route. The rats from individual group were sacrificed on 3rd day, 7th day and 14th day and stomachs were examined under light microscope to observe the inflammatory cells infiltration.Results: Gross and microscopic findings on days 3, 7 and 14 were similar. Control groups A1, A2 and A3 showed normal healthy gastric mucosa and the least number of inflammatory cells. In group B, aspirin produced ulcerations and linear breaks; with highest inflammatory infiltrates. On microscopic examination, numerous inflammatory cells were noted. Group C and D rats had minimum ulcer index and fewer inflammatory cells.Conclusions: Acacia catechu has protective role against gastric injury by inhibiting inflammation. 

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